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sushantsuresh.bsky.social
Sushant Suresh
@sushantsuresh.bsky.social
23 followers 32 following 2 posts
PhD candidate in the John Burke lab at University of Victoria | Structural Biology | HDX-MS | lipid kinases
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sushantsuresh.bsky.social
Sushant Suresh @sushantsuresh.bsky.social · Aug 7
Great collaborative work where we developed a nanobody based tool to block EFR3 mediated recruitment of PI4KA. A potential therapeutic window maybe?
Thanks @alexlouiseshaw.bsky.social for the assist!
alexlouiseshaw.bsky.social
Alexandria Shaw @alexlouiseshaw.bsky.social · Aug 6
New preprint from the lab headed up by
@sushantsuresh.bsky.social! Late last year, we published the molecular basis of PI4KA plasma membrane recruitment by EFR3 (PMID:39705356). This work builds on these findings and identifies a new potential therapeutic avenue! Check it out!
biorxivpreprint.bsky.social
bioRxivpreprint @biorxivpreprint.bsky.social · Aug 1
Development of an inhibitory TTC7B selective nanobody that blocks EFR3 recruitment of PI4KA https://www.biorxiv.org/content/10.1101/2025.07.28.667261v1
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Reposted by Sushant Suresh
alexlouiseshaw.bsky.social
Alexandria Shaw @alexlouiseshaw.bsky.social · Aug 6
New preprint from the lab headed up by
@sushantsuresh.bsky.social! Late last year, we published the molecular basis of PI4KA plasma membrane recruitment by EFR3 (PMID:39705356). This work builds on these findings and identifies a new potential therapeutic avenue! Check it out!
biorxivpreprint.bsky.social
bioRxivpreprint @biorxivpreprint.bsky.social · Aug 1
Development of an inhibitory TTC7B selective nanobody that blocks EFR3 recruitment of PI4KA https://www.biorxiv.org/content/10.1101/2025.07.28.667261v1
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sushantsuresh.bsky.social
Sushant Suresh @sushantsuresh.bsky.social · Jan 6
Back from vacation and really glad to share some work from my PhD research. Great collaborative effort @alexlouiseshaw.bsky.social Check out this post from my PI to learn more about Lipid kinase PI4KA and its regulation!
jburkevic.bsky.social
John Burke @jburkevic.bsky.social · Dec 20
First post up, sharing some cool work from my lab by @alexlouiseshaw.bsky.social and @sushantsuresh.bsky.social out today in Science Advances (www.science.org/doi/10.1126/...)
Molecular basis for plasma membrane recruitment of PI4KA by EFR3
The structure of the EFR3A-PI4KA complex reveals insight into PI4KA membrane localization and its role in human disease.
www.science.org
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