Stogiegoat🔞🐐
@stogiegoat.bsky.social
🔞 Bluesky home of StogieGoatArts. The goat-noodle that likes to doodle! Picarto TV Stream http://picarto.tv/StogieGoatArts
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You will be visited by three spirits
December 9, 2025 at 3:56 PM
You will be visited by three spirits
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Tatas for Toys benefit has made it rain $183,000 over the past 14 years.
Strippers Are Now No. 1 Donor of Toys to Children’s Hospital
Rachel Saslow
www.wweek.com
December 9, 2025 at 12:22 AM
Tatas for Toys benefit has made it rain $183,000 over the past 14 years.
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that checkpoint inhibitor drugs such as anti-PD-1 therapy -already used in hospitals- work best when they expand these stem-like and metabolically fit T-cells. In contrast, people whose immune reactions were regulated by exhausted cells fared badly. When checkpoint therapy was administered with
December 9, 2025 at 5:07 PM
that checkpoint inhibitor drugs such as anti-PD-1 therapy -already used in hospitals- work best when they expand these stem-like and metabolically fit T-cells. In contrast, people whose immune reactions were regulated by exhausted cells fared badly. When checkpoint therapy was administered with
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“stem-like" T-cells. These cells, characterized by genes TCF1 and LEF1, could self-renew and differentiate into new waves of fighters. If these cells were removed from mouse models, immune attacks collapsed; if they were grown, tumors disappeared and survival increased. Researchers also discovered
December 9, 2025 at 5:06 PM
“stem-like" T-cells. These cells, characterized by genes TCF1 and LEF1, could self-renew and differentiate into new waves of fighters. If these cells were removed from mouse models, immune attacks collapsed; if they were grown, tumors disappeared and survival increased. Researchers also discovered
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chemical messenger that recruits other immune defenses. The studies showed that metabolic flexibility, not target recognition, foretells how long the immune cells will keep fighting. Among the populations of tumor-infiltrating T-cells that were so diverse, one stood out as extraordinary: a subset of
December 9, 2025 at 5:06 PM
chemical messenger that recruits other immune defenses. The studies showed that metabolic flexibility, not target recognition, foretells how long the immune cells will keep fighting. Among the populations of tumor-infiltrating T-cells that were so diverse, one stood out as extraordinary: a subset of
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glycolysis, they switched to oxidative phosphorylation and fatty acid metabolism- an energy strategy that enables them to endure the long term. When researchers boosted these channels of energy in mice, the T-cells killed tumor cells better and produced higher levels of interferon-γ, an immune
December 9, 2025 at 5:05 PM
glycolysis, they switched to oxidative phosphorylation and fatty acid metabolism- an energy strategy that enables them to endure the long term. When researchers boosted these channels of energy in mice, the T-cells killed tumor cells better and produced higher levels of interferon-γ, an immune
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single-cell resolution, the researchers identified a minor subset of tumor-cytotoxic cells. These cells continue to function even in oxygen-starved, nutrient-poor environments in which other immune cells do not. These hardy T-cells employed a second fuel source. Instead of combusting glucose through
December 9, 2025 at 5:05 PM
single-cell resolution, the researchers identified a minor subset of tumor-cytotoxic cells. These cells continue to function even in oxygen-starved, nutrient-poor environments in which other immune cells do not. These hardy T-cells employed a second fuel source. Instead of combusting glucose through
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patients, the treatments fail because immune cells become exhausted. Tumors naturally adapt to disable or tire out the same cells meant to kill them. Researchers mapped how CD8⁺ T cells-the body's own killers-are capable of surviving and fighting within solid tumors. By examining the cells at
December 9, 2025 at 5:04 PM
patients, the treatments fail because immune cells become exhausted. Tumors naturally adapt to disable or tire out the same cells meant to kill them. Researchers mapped how CD8⁺ T cells-the body's own killers-are capable of surviving and fighting within solid tumors. By examining the cells at
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place. Taken together, the breakthroughs promise a day when the body's own immune system can prevent and fight cancer with greater accuracy and endurance. Cancer immunotherapy transformed the treatment of most cancers by unleashing the potential of the immune system to kill tumors. Yet, in most
December 9, 2025 at 5:04 PM
place. Taken together, the breakthroughs promise a day when the body's own immune system can prevent and fight cancer with greater accuracy and endurance. Cancer immunotherapy transformed the treatment of most cancers by unleashing the potential of the immune system to kill tumors. Yet, in most
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In a breakthrough that could potentially rewrite the prevention and treatment of cancer, researchers have discovered how certain immune cells can break through tumors’ defenses. They have also developed a new nanoscale vaccine that shows promise in preventing cancers from occurring in the first
December 9, 2025 at 5:03 PM
In a breakthrough that could potentially rewrite the prevention and treatment of cancer, researchers have discovered how certain immune cells can break through tumors’ defenses. They have also developed a new nanoscale vaccine that shows promise in preventing cancers from occurring in the first
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Melanoma, pancreatic cancer, and triple-negative breast cancer (TNBC) are each serious clinical challenges due to how common or aggressive they are and how poorly they often respond to treatment. Which is why researchers are determined to develop an effective treatment for all of them.
December 9, 2025 at 5:03 PM
Melanoma, pancreatic cancer, and triple-negative breast cancer (TNBC) are each serious clinical challenges due to how common or aggressive they are and how poorly they often respond to treatment. Which is why researchers are determined to develop an effective treatment for all of them.
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Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types. NOTE: This is PRECLINICAL.
• www.umass.edu/news/article...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
• www.umass.edu/news/article...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
December 9, 2025 at 5:02 PM
Researchers envision their vaccine being used as both a treatment and a preventive, and as an approach to treating multiple cancer types. NOTE: This is PRECLINICAL.
• www.umass.edu/news/article...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
• www.umass.edu/news/article...
The study has been published in Cell. YES, it is PEER-REVIEWED.
• www.cell.com/cell-reports...
🧪🧵⬇️
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GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.
December 9, 2025 at 5:00 PM
GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.
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The Yule Goat had a blast at Krampusnacht with @lycanwitch.art this weekend! 🤘👹🤘
December 9, 2025 at 1:54 PM
The Yule Goat had a blast at Krampusnacht with @lycanwitch.art this weekend! 🤘👹🤘
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you will be visited by 3 spirits
December 9, 2025 at 12:00 AM
you will be visited by 3 spirits
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December 9, 2025 at 7:42 AM
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Everyone imitates Tolkien all the time except when it comes to the one way it would really matter: making the protagonist of your novel for children a short, fat, 50-year-old man who doesn't want to do anything.
December 9, 2025 at 2:40 AM
Everyone imitates Tolkien all the time except when it comes to the one way it would really matter: making the protagonist of your novel for children a short, fat, 50-year-old man who doesn't want to do anything.
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If you exist inside a creator safe spaces you contribute to a positive presence. Even if you're not actively partaking in creating, you help someone else to. Don't ever feel undervalued or unseen, someone out there is rendering videos, drawing lines or putting words to paper hoping you'll enjoy it.
shout out to all furries who don’t even do art
never think less of yourself
we are glad to have your company
never think less of yourself
we are glad to have your company
December 9, 2025 at 5:15 AM
If you exist inside a creator safe spaces you contribute to a positive presence. Even if you're not actively partaking in creating, you help someone else to. Don't ever feel undervalued or unseen, someone out there is rendering videos, drawing lines or putting words to paper hoping you'll enjoy it.
Reposted by Stogiegoat🔞🐐
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DDDD day5: subtle hints.
December 8, 2025 at 9:31 PM
DDDD day5: subtle hints.
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Rebecca Cunningham, from "Tailspin".
Doodle request from my fine patrons - patreon.com/collectedcur...
Doodle request from my fine patrons - patreon.com/collectedcur...
November 11, 2025 at 9:36 AM
Rebecca Cunningham, from "Tailspin".
Doodle request from my fine patrons - patreon.com/collectedcur...
Doodle request from my fine patrons - patreon.com/collectedcur...
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Commission for Glace💦
December 8, 2025 at 5:15 PM
Commission for Glace💦
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"Stranger Things is selling you Nostalgia."
Yes. So was Grease or Happy Days or American Graffiti.
I. Don't. Give. A. Fuck. 🖕
That's part of why I like it. 👍
Yes. So was Grease or Happy Days or American Graffiti.
I. Don't. Give. A. Fuck. 🖕
That's part of why I like it. 👍
December 7, 2025 at 7:55 AM
"Stranger Things is selling you Nostalgia."
Yes. So was Grease or Happy Days or American Graffiti.
I. Don't. Give. A. Fuck. 🖕
That's part of why I like it. 👍
Yes. So was Grease or Happy Days or American Graffiti.
I. Don't. Give. A. Fuck. 🖕
That's part of why I like it. 👍
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I will accept no questions.
December 8, 2025 at 12:03 AM
I will accept no questions.