Sandra Bos
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sandrabos.bsky.social
Sandra Bos
@sandrabos.bsky.social
230 followers 620 following 12 posts
Research assistant professor PI, Cross Flavi Lab @Pitt | Flavivirus antibody response & cross-flavivirus interactions | Epidemiology & Capacity Building | UC Berkeley affiliate
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Reposted by Sandra Bos
cidrap.bsky.social
CIDRAP joins global partners in the DeZi Network — uniting 15+ countries to strengthen dengue & Zika surveillance and response across Africa and Asia.

🔗 www.imperial.ac.uk/news/269973/...

#GlobalHealth #Dengue #Zika
International collaborative effort to understand dengue and Zika | Imperial News | Imperial College London
An international team launched the DeZi network to understand how the viruses spread, interact, and cause disease across Africa and Asia.
www.imperial.ac.uk
November 4, 2025 at 6:56 PM
Reposted by Sandra Bos
mrc-outbreak.bsky.social
Today we're kickstarting the Dengue & Zika Immunology & Genomics Multi-Country (DeZi) Network funded by @wellcometrust.bsky.social with contributions from @temasek.bsky.social @neasg.bsky.social #UNITEDengue
@imperialcollegeldn.bsky.social @nfaria.bsky.social
www.imperial.ac.uk/news/269973/...
International collaborative effort to understand dengue and Zika | Imperial News | Imperial College London
An international team launched the DeZi network to understand how the viruses spread, interact, and cause disease across Africa and Asia.
www.imperial.ac.uk
November 4, 2025 at 9:23 AM
sandrabos.bsky.social
I’m pleased to announce the launch of #DeZi ! a global collaboration funded by @wellcometrust.bsky.social and led by @imperialcollegeldn.bsky.social that brings together teams across Africa, Asia & the Americas to advance our understanding of #dengue & #Zika viruses

Thread DeZi in brief 👇
Dear network, I’m pleased to announce the launch of hashtag#DeZi (Dengue and Zika Immunology and Genomics Multi-Country Network) – a global collaboration that I’m part of, bringing together leading teams across Africa, Asia, and the Americas to advance our understanding of dengue and Zika viruses. 🔬 DeZi in brief: DeZi is a global initiative led by Imperial College London and Nuno R. Faria and supported by the Wellcome Trust, Temasek Foundation and the National Environment Agency. It integrates genomics, serology, and modelling to map the burden, transmission, and evolution of dengue and Zika viruses. By combining innovation with equitable partnerships, DeZi aims to: • accelerate the adoption of improved diagnostics • strengthen regional laboratory capacity and South–South collaborations • enhance preparedness for future arboviral epidemics in a changing climate With its open-access resources and policy engagement activities DeZi will help countries integrate the surveillance of dengue, Zika, and other mosquito-borne viruses into routine national health systems, turning collaboration into capacity, and data into effective policymaking. 🌍 Partners span research institutions and public-health laboratories in more than 15 countries across Africa, Asia, and Latin America, working closely with UKHSA, Yale University, WHO, and networks such as UNITEDengue, CREID, and ARTIC2.0.
November 7, 2025 at 2:38 PM
sandrabos.bsky.social
𝐖𝐡𝐲 𝐝𝐨 𝐬𝐨𝐦𝐞 𝐩𝐞𝐨𝐩𝐥𝐞 𝐝𝐞𝐯𝐞𝐥𝐨𝐩 𝐬𝐞𝐯𝐞𝐫𝐞 𝐝𝐞𝐧𝐠𝐮𝐞 𝐰𝐡𝐢𝐥𝐞 𝐨𝐭𝐡𝐞𝐫𝐬 𝐝𝐨𝐧’𝐭 — 𝐞𝐯𝐞𝐧 𝐰𝐡𝐞𝐧 𝐢𝐧𝐟𝐞𝐜𝐭𝐞𝐝 𝐛𝐲 𝐭𝐡𝐞 𝐬𝐚𝐦𝐞 𝐯𝐢𝐫𝐮𝐬? In our latest paper in Cell Reports, we show that the answer may lie in pre-existing cross-reactive antibodies. www.cell.com/cell-reports...

🔍 𝐊𝐞𝐲 𝐈𝐧𝐬𝐢𝐠𝐡𝐭𝐬 in comments
Anti-dengue virus antibodies that elicit complement-mediated lysis of Zika virion correlate with protection from severe dengue disease
Dias et al. show that cross-reactive anti-dengue virus antibodies in pre-infection plasma that mediate complement-dependent virolysis of Zika virus correlate with protection from subsequent severe den...
www.cell.com
November 4, 2025 at 5:08 PM
sandrabos.bsky.social
Check out our paper in @natcomms.nature.com !
We explored the link between pre-existing neutralizing antibody (nAb) titers and dengue disease protection & how different cell substrate and virus maturation state influences the measurement of nAb titers

rdcu.be/eOfXW
Protection against symptomatic dengue infection by neutralizing antibodies varies by infection history and infecting serotype
Nature Communications - There is still a need to improve understanding of dengue-specific immunity. Here, by analyzing the antibody response in a pediatric cohort the authors show that the...
rdcu.be
November 4, 2025 at 4:57 PM
Reposted by Sandra Bos
vasilakislab.bsky.social
Monumental effort led by Peter Simmonds and Jens Kuhn to reorganize the Family Flaviviridae based on analysis of RNA-directed RNA polymerase (RdRP) hallmark gene sequences is finally out. Enjoy reading. #ICTV @utmbhealth.bsky.social @astmh.bsky.social @sbvirologia.bsky.social
October 31, 2025 at 12:44 PM