Renil Mathew
@renilmathew.bsky.social
Neuroscience PhD student, Western University 🇨🇦. Multimodal fMRI 🐒 👳🏾♂️
Pinned
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI - Nature Methods
Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with acquisition-free perio...
www.nature.com
Excited to share my first first-author paper in Nature Methods!🤩
A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...
A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...
Reposted by Renil Mathew
#WesternU researchers have unlocked the hidden potential in discarded MRI data, developing a new technique transforming how scientists study the brain. @schulichmeddent.bsky.social
Signal in the silence: Western researchers uncover hidden potential in discarded MRI data - Western News
Western University researchers have uncovered hidden potential in the historically discarded MRI data that is recorded in start-up period of scans.
buff.ly
November 14, 2025 at 8:07 PM
#WesternU researchers have unlocked the hidden potential in discarded MRI data, developing a new technique transforming how scientists study the brain. @schulichmeddent.bsky.social
Reposted by Renil Mathew
Researchers at @westernu.ca have unlocked surprising power in the first seconds of a functional MRI scan. Short, deliberate pauses boost the signal that follows – producing sharper, more responsive images of brain activity.
Published today in @natmethods.nature.com.
Published today in @natmethods.nature.com.
Signal in the silence: Researchers uncover hidden potential in discarded MRI data - Schulich School of Medicine & Dentistry - Western University
A new technique is transforming how scientists use fMRI to study the brain.
www.schulich.uwo.ca
November 13, 2025 at 1:42 PM
Researchers at @westernu.ca have unlocked surprising power in the first seconds of a functional MRI scan. Short, deliberate pauses boost the signal that follows – producing sharper, more responsive images of brain activity.
Published today in @natmethods.nature.com.
Published today in @natmethods.nature.com.
Reposted by Renil Mathew
If the community wants, we have XA60 and VE12U versions we can make available as a C2P for Siemens scanners. And we have a Paravision 360 v3.6 available for Bruker. The processing code is equally simple and is posted with the paper.
14 months after submission, our article “Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI" is now out in @natmethods.nature.com . You can read it here rdcu.be/ePJo6
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI
Nature Methods - Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with...
rdcu.be
November 13, 2025 at 3:55 PM
If the community wants, we have XA60 and VE12U versions we can make available as a C2P for Siemens scanners. And we have a Paravision 360 v3.6 available for Bruker. The processing code is equally simple and is posted with the paper.
Reposted by Renil Mathew
This article in The Transmitter covering our paper may be one of the best scientific content headlines of all time. www.thetransmitter.org/fmri/timing-...
Timing tweak turns trashed fMRI scans into treasure
Leveraging start-up “dummy scans,” which are typically discarded in imaging analyses, can shorten an experiment’s length and make data collection more efficient, a new study reveals.
www.thetransmitter.org
November 13, 2025 at 12:29 PM
This article in The Transmitter covering our paper may be one of the best scientific content headlines of all time. www.thetransmitter.org/fmri/timing-...
Super excited about my first first-author paper, now out in @natmethods.nature.com 🥳
14 months after submission, our article “Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI" is now out in @natmethods.nature.com . You can read it here rdcu.be/ePJo6
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
It is the first first author paper from my student @renilmathew.bsky.social 👏🏽👏🏽👏🏽 …1/N
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI
Nature Methods - Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with...
rdcu.be
November 13, 2025 at 12:27 PM
Super excited about my first first-author paper, now out in @natmethods.nature.com 🥳
Excited to share my first first-author paper in Nature Methods!🤩
A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...
A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...
Stimulus-modulated approach to steady state (SASS): a flexible paradigm for event-related fMRI - Nature Methods
Stimulus-modulated approach to steady state (SASS) is an acquisition scheme for event-related fMRI that generates data with high temporal signal-to-noise ratios interspaced with acquisition-free perio...
www.nature.com
November 13, 2025 at 11:48 AM
Excited to share my first first-author paper in Nature Methods!🤩
A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...
A quest to solve fMRI–EEG interference revealed a hidden strength in the usually discarded “dummy” scans. That spark became SASS-fMRI — boosting sensitivity and enabling silent, flexible experiments.
www.nature.com/articles/s41...
Reposted by Renil Mathew
On this day in 1920, Dr. Frederick Banting woke at 2 a.m. in #LdnOnt and jotted down a 25-word idea — setting in motion the discovery of insulin.
105 years later, Banting's legacy continues. A heritage plaque at #WesternU now marks the historic moment.
Learn more: www.uwo.ca/projects/her...
105 years later, Banting's legacy continues. A heritage plaque at #WesternU now marks the historic moment.
Learn more: www.uwo.ca/projects/her...
October 31, 2025 at 5:25 PM
On this day in 1920, Dr. Frederick Banting woke at 2 a.m. in #LdnOnt and jotted down a 25-word idea — setting in motion the discovery of insulin.
105 years later, Banting's legacy continues. A heritage plaque at #WesternU now marks the historic moment.
Learn more: www.uwo.ca/projects/her...
105 years later, Banting's legacy continues. A heritage plaque at #WesternU now marks the historic moment.
Learn more: www.uwo.ca/projects/her...
Thrilled to share that the central work of my PhD will be published soon.😬
A lot of hard work over a year went into this. Details to follow when the embargo lifts! What I can say is that good peer review can make a paper much better, even if it takes a year. And these peer reviewers were very helpful and constructive 🙏. You'll be able to read their comments online.
October 11, 2025 at 5:32 PM
Thrilled to share that the central work of my PhD will be published soon.😬
Reposted by Renil Mathew
A new open source nonsurgical head restraint for awake mouse fMRI from our lab led by Sam Laxer. TL;DR Scanning about 25% longer than with a surgically implanted head post, combined with some training gives good results. Happy mice = happy rsfmri networks. direct.mit.edu/imag/article...
A non-invasive approach to awake mouse fMRI compatible with multi-modal techniques
Abstract. Mouse functional magnetic resonance imaging (fMRI) studies contribute significantly to basic fundamental and translational neuroscience research. Performing fMRI in awake mice could facilita...
direct.mit.edu
September 22, 2025 at 9:13 PM
A new open source nonsurgical head restraint for awake mouse fMRI from our lab led by Sam Laxer. TL;DR Scanning about 25% longer than with a surgically implanted head post, combined with some training gives good results. Happy mice = happy rsfmri networks. direct.mit.edu/imag/article...
Reposted by Renil Mathew
ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis.
www.thetransmitter.org/human-neurot...
www.thetransmitter.org/human-neurot...
fMRI can do more than you think
Advances in brain imaging technology provide new and different information about the brain.
www.thetransmitter.org
June 25, 2025 at 4:19 PM
ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis.
www.thetransmitter.org/human-neurot...
www.thetransmitter.org/human-neurot...
Reposted by Renil Mathew
We're excited share our perspective on whether you only use 10 bits/s of your brain.
Is it true you use only 10 bits / s of your brain?
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...
@andpru.bsky.social and I provide a motor systems perspective on a proposed speed limit for human information processing. Out today in
@natneuro.nature.com:
www.nature.com/articles/s41...
sky.social
June 13, 2025 at 2:22 PM
We're excited share our perspective on whether you only use 10 bits/s of your brain.
Reposted by Renil Mathew
Human neuroscience research has largely overlooked the mesoscale, which bridges cells and brain areas. But new advances in fMRI technology are changing that, writes Laurentius Huber @layerfmri.bsky.social.
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
Imaging cortical layers to understand brain as network organ
This spatial scale, bridging cells and brain areas, has been overlooked in human brain research. But advances in fMRI technology are changing that.
www.thetransmitter.org
June 2, 2025 at 3:28 PM
Human neuroscience research has largely overlooked the mesoscale, which bridges cells and brain areas. But new advances in fMRI technology are changing that, writes Laurentius Huber @layerfmri.bsky.social.
#neuroskyence
www.thetransmitter.org/future-of-fm...
#neuroskyence
www.thetransmitter.org/future-of-fm...
New revised preprint on the SASS paradigm now with extensive human experiments, showing its broader applicability—check it out!
In response to very perceptive reviewers comments we have now posted an updated preprint of our original 9.4 T SASS approach that was downloaded over 1000 times. TL;DR It works at 3 T under defined conditions. Read all about itt here…https://www.biorxiv.org/content/10.1101/2024.09.20.613944v3
Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI.
Functional MRI (fMRI) studies discard the initial volumes acquired during the approach of the magnetization to its steady-state value. Here, we leverage the higher temporal signal-to-noise ratio (tSNR...
www.biorxiv.org
May 28, 2025 at 8:56 PM
New revised preprint on the SASS paradigm now with extensive human experiments, showing its broader applicability—check it out!
Reposted by Renil Mathew
Western University is seeking applications for Canada Excellence Research Chairs. Please reach out if you are interested in Theme 2: Neuroscience. Western has extraordinary strengths in cognitive, molecular and systems neuroscience across species (rodents, NHPs, humans) uwo.ca/research/cer...
May 5, 2025 at 10:47 PM
Western University is seeking applications for Canada Excellence Research Chairs. Please reach out if you are interested in Theme 2: Neuroscience. Western has extraordinary strengths in cognitive, molecular and systems neuroscience across species (rodents, NHPs, humans) uwo.ca/research/cer...
Reposted by Renil Mathew
If you would like to postdoc in ultra high field MRI (3T+7T human, 9.4T+15.2T marmoset and mouse) in a well funded lab with tons of great neuroscience collaborations, drop me a DM soon.
Western Postdoctoral Fellowship Program
Western University, in vibrant London, Ontario, delivers an academic and student experience second to none.
uwo.ca
March 6, 2025 at 6:02 PM
If you would like to postdoc in ultra high field MRI (3T+7T human, 9.4T+15.2T marmoset and mouse) in a well funded lab with tons of great neuroscience collaborations, drop me a DM soon.
Reposted by Renil Mathew
Since I have a new set of followers here, I thought I'd repost a link to our preprint that describes a new event related fMRI method that allows 2x the SNR of normal fMRI and beautiful single unit and EEG recordings, dead silence to present auditory stimuli etc. 1/2
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Stimulus-modulated approach to steady-state: A new paradigm for event-related fMRI
Functional MRI (fMRI) studies discard the initial volumes acquired during the approach of the magnetization to its steady-state value. Here, we leverage the substantially higher temporal signal-to-noi...
www.biorxiv.org
December 3, 2024 at 7:00 PM
Since I have a new set of followers here, I thought I'd repost a link to our preprint that describes a new event related fMRI method that allows 2x the SNR of normal fMRI and beautiful single unit and EEG recordings, dead silence to present auditory stimuli etc. 1/2
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...