Blelloch Lab UCSF
            
            @rblellochlab.bsky.social
          
          140 followers
          120 following
          3 posts
        
          We are interested in uncovering fundamental mechanisms of cell fate in normal mammalian development and disease. Our current interests are in tumor immunology, placental development and stem cell engineering.  |@UCSF | @UCSFStemcell | @UCSFUrology
      
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      🚨 New Paper Alert! 🚨 
Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️
      
          Our latest study on KMT2C/KMT2D (mutated in 20% of cancers) reveals a new function for H3K4me1 in regulating DNA replication timing (RT) and origin activity during cell state transitions. Check it out: www.cell.com/cell-reports.... More info ⬇️
KMT2C/KMT2D-dependent H3K4me1 mediates changes in DNA replication timing and origin activity during a cell fate transition
          Gökbuget et al. use machine learning to quantify chromatin state changes that predict
DNA replication timing changes during cell differentiation. By following up on top
predictors through functional v...
        
          
          www.cell.com
        
      
  
        
      Reposted by Blelloch Lab UCSF
    
  
        
      Reposted by Blelloch Lab UCSF
    
  
          
              Oliver Harschnitz
              @harschnitz.bsky.social
          
              · Nov 20
        
        
      
    
        
      Reposted by Blelloch Lab UCSF
    
  
        
      Reposted by Blelloch Lab UCSF
    
  
          
              Oliver Harschnitz
              @harschnitz.bsky.social
          
              · Nov 11
        
        
      
    
        
      Reposted by Blelloch Lab UCSF
    
  
          
              Abby Dernburg
              @adernburg.bsky.social
          
              · Nov 12
        
        
        
            With Trump coming into power, the NIH is in the crosshairs
            The National Institutes of Health, the crown jewel of biomedical research in the U.S., could face big changes under the new Trump administration, some fueled by pandemic-era criticisms of the agency.
          
            
            www.npr.org
          
        
      
    
        
      Reposted by Blelloch Lab UCSF