Hongrui Liu
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rayliulhr.bsky.social
Hongrui Liu
@rayliulhr.bsky.social
JHU PhD researcher sharing the human stories behind scientific discovery — the surprises, struggles, and sparks beyond the figures.
Excited to share our new Nature study on the bowhead whale, a species that can live over 200 years with low cancer rates. We found that bowhead cells repair DNA breaks with striking efficiency, helped by high levels of CIRBP, a RNA/PAR-binding protein that boosts accurate repair.

#Nature #DNARepair
Evidence for improved DNA repair in the long-lived bowhead whale - Nature
Analysis of the longest-lived mammal, the bowhead whale, reveals an improved ability to repair DNA breaks, mediated by high levels of cold-inducible RNA-binding protein.  &nbs...
www.nature.com
December 10, 2025 at 4:41 PM
I’ll be presenting at this week’s BMB Research Colloquium on how PAR triggers sustained FUS condensation (hysteresis) in DNA repair.
📍 JHSPH W3030
🕥 Thu, Dec 11 | 10:30 AM
All welcome!
Poster credit: Maranda
#DNARepair #PhaseSeparation #BiomolecularCondensates #PAR #FUS #Science
December 6, 2025 at 1:55 AM
Check out our review of PARPs and ADP-ribosylation-mediated biomolecular condensates. This is, by the way, my first review paper!
Available online - the Review "PARPs and ADP-ribosylation-mediated #biomolecularcondensates: determinants, dynamics, and disease implications" from @leunglab.bsky.social and colleagues.

#phaseseparation #proteincondensation #proteinaggregation

Free access at: authors.elsevier.com/a/1kZlO3S6Gf...
February 19, 2025 at 6:32 PM
Sugarloaf sunset
December 1, 2024 at 9:45 PM
Welcome to Appalachian Mountains!
November 23, 2024 at 2:11 PM