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prudenciolab.bsky.social
@prudenciolab.bsky.social
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rossolllab.bsky.social
Wilfried Rossoll @rossolllab.bsky.social · Mar 13
Our proximity proteomics study introducing Probe‑dependent Proximity Profiling (ProPPr) and applying it for profiling tau pathology‑associated proteins in tauopathies + @drneurochic.bsky.social & others is out now! @cziscience.bsky.social
molecularneurodegeneration.biomedcentral.com/articles/10....
Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies - Molecular Neurodegeneration
Background Tauopathies represent a diverse group of neurodegenerative disorders characterized by the abnormal aggregation of the microtubule-associated protein tau. Despite extensive research, the mec...
molecularneurodegeneration.biomedcentral.com
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prudenciolab.bsky.social
prudenciolab.bsky.social @prudenciolab.bsky.social · Apr 5
I was thrilled for the opportunity to present today #ADPD2025 the work @PrudencioLab, in the wonderful city of Vienna where I was lucky to get an awesome tour by Dr Wilfried Rossoll! @rossolllab.bsky.social
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prudenciolab.bsky.social
prudenciolab.bsky.social @prudenciolab.bsky.social · Apr 3
Our manuscript got highlighted with a beautiful infographic!

#TDP43 #PerrySyndrome #Neurodegeneration #RNAsplicing #Biomarkers #Neuroscience #FTLD #ALS #PrudencioLab

DOI: lnkd.in/eXr8te8A
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prudenciolab.bsky.social
prudenciolab.bsky.social @prudenciolab.bsky.social · Jan 10
Excited to finally publish our work on cryptic splicing in Perry syndrome. Moreover, it higlights that not all cryptic RNAs are detected in every brain region with TDP-43 pathology. Enjoy!

movementdisorders.onlinelibrary.wiley.com/doi/10.1002/...
TDP‐43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP‐43 Proteinopathies
In Perry syndrome caudate nucleus, TDP-43 pathology and dysfunction lead to the cryptic splicing of eight RNA targets as well as HDGFL2 cryptic protein. In the substantia nigra, only one cryptic targ....
movementdisorders.onlinelibrary.wiley.com
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