Profolus
@profolus.com
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Explainers on business and markets, science and tech, health and medicine, and society and culture. www.profolus.com
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Recent polls following the first couple of months of Donald Trump in office indicate he is on his way to becoming the most hated U.S. president at first-year mark in U.S. history.

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Findings from a Chinese study showed that chemotherapy, while essential in shrinking tumors, may paradoxically accelerate cancer spread by awakening dormant cells.
How Chemotherapy May Speed Up Cancer Spread—Chinese Researchers Explain - Profolus
Research shows chemotherapy can paradoxically accelerate cancer or lead to cancer recurrence after remission.
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Researchers at Brown University found that individuals with extreme political views demonstrated more similar brain activity to each other, regardless of being left-leaning or right-leaning, compared to moderates.
Horseshoe Observed: Far-Right and Far-Left U.S. Adults Exhibit Similar Neural Processing - Profolus
Brain imaging study finds surprising similarities between U.S. political extremes.
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They began disagreeing about politics. Then they stopped agreeing on reality. A new study by communication scholar Emily Van Duyn reveals how false information breaks not only democracies but also romantic relationships.
Misinformation and Disinformation Can Disrupt Romantic Relationships - Profolus
A research provides insights on how misinfiromation and disinformation transform romance into division.
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The 2025 Nobel Prize in Physiology or Medicine celebrates a series of discoveries that redefined immunity. Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi uncovered how the immune system knows when to fight—and when to stand down.
Nobel-Winning Discovery: Explaining Peripheral Immune Tolerance - Profolus
The 2025 Nobel Prize in Physiology Medicine honors Mary Brunkow, Fred Ramsdell, and Shimon Sakaguchi for their discoveries on peripheral immune tolerance.
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What seemed a negligible spark on a rugged trail would transform into a raging inferno that consumed homes and lives within days. Federal prosecutors allege Uber driver Jonathan Rinderknecht started the blaze that became the 2025 Palisades Fire.
Jonathan Rinderknecht: How Authorities Linked Him to Palisades Fire - Profolus
Federal investigators have charged Uber driver Jonathan Rinderknecht for allegedly igniting the 2025 Palisades Fire in Los Angeles.
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While the Gaza ceasefire offers a moment of relief, experts caution that without accountability, political inclusion, and legal safeguards, it could entrench power imbalances rather than resolve them.
Explaining the 2025 Gaza War Peace Plan and 2025 Gaza Ceasefire - Profolus
A 20-point peace plan proposed by the United States is reshaping the conversation around the future of Gaza.
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The U.S. produces over 30 billion board feet of lumber each year. However, despite its significant domestic production, it still needs to import lumber and timber to meet its consumption needs.
Why is Timber More Popular than Concrete in the U.S. - Profolus
Timber dominates U.S. residential building and other construction undertakings. This contrasts with building practices in Europe and Asia.
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Sociologists Alexander Yendell and David Herbert found that gender-based views legitimizing violence, authoritarian tendencies, and specific dark personality traits were central predictors of generalized war support.
Beliefs About Violent Masculinity May Predict Readiness for War - Profolus
Beliefs linking masculinity with violence are the strongest driver of pro-war attitudes.
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KONSYSE: A federal judge has blocked new restrictions on grants for domestic violence programs across the country. Judge Melissa DuBose ruled that enforcing the new grant rules could disrupt critical support programs.
Rhode Island Judge Ruled Trump Cannot Put Conditions On Domestic Violence Grants — Konsyse
Judge Melissa DuBose issued an injunction preventing federal agencies from restricting funding based on diversity or abortion-related services.
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Nearly anyone born on United States soil, including territories like Guam and Puerto Rico, is automatically considered a U.S. citizen. This is called birthright citizenship by virtue of jus soli or right of the soil.
Why Does the United States Have Birthright Citizenship? - Profolus
Nearly anyone born on United States soil is automatically considered a U.S. citizen. This is called birthright citizenship.
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KONSYSE: Naked mole-rats may hold the molecular blueprint for aging more slowly. Researchers have traced their resilience to unexpected changes in a single protein.
Unique Naked Mole-Rat Protein May Guide Future Human Anti-Aging Research — Konsyse
Scientists studying naked mole rats have identified four amino acid changes in a key protein that enhance DNA repair.
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Few national events in the U.S. reveal the fragility of public systems like a government shutdown. This event might not be an excessively dramatic situation, but it demonstrates how one missed budget vote due to partisan differences unravels the machinery of governance.
What Happens During A U.S. Government Shutdown? Is It Really That Serious? - Profolus
A government shutdown occurs when the U.S. Congress fails to fund federal operations.
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KONSYSE: From drone incursions to propaganda, Europe faces a new kind of conflict—one that operates in the shadows. European Commission President Ursula von der Leyen urges unity and modernization of defense to resist the Russian “grey zone” campaign.
European Commission President Warns Russia is Waging a Grey Zone Campaign Against Europe — Konsyse
European Commission President Ursula von der Leyen calls for collective action as Russia escalates covert hybrid warfare across the continent.
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A 37-storey building standing on a 0.25 hectare of land was able to produce 3500 tons of different fruits and vegetables. In traditional farming, producing mere 30 to 40 tons of high-yield vegetables, will require a hectare of land.
Vertical Farming: Advantages and Disadvantages - Profolus
A discussion of the opportunities and advantages, as well as challenges, limitations, and disadvantages of vertical farming
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KONSYSE: Lucid dreamers tend to have a larger anterior prefrontal cortex—an area in the brain that enables self-reflection or metacognition. They are more likely to self-reflect and have a considerable degree of personal awareness when they are awake.
Link Between Lucid Dreaming and Metacognition — Konsyse
Researchers discovered lucid dreaming relates to larger anterior prefrontal cortex—a brain area associated with metacognition.
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People from ancient times were already implementing loose systems of ascribing value to a particular object. For example, in Mesopotamia around 4000 BCE, clay tablets were used to inscribe official records of debts.
Origin and History of Money: From Clay Tablets to Legal Tenders - Profolus
A discussion of the origin and history of money, including the different mediums of exchange used in the ancient and modern times.
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KONSYSE: Immigration and Customs Enforcement is advancing a program that would station analysts in targeting centers to examine digital activity and convert findings into enforcement leads.
Records Show ICE is Building 24/7 Social Media Surveillance — Konsyse
Immigration and Customs Enforcement is preparing a 24/7 social media monitoring system using contractors.
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There was no abundant amount of free oxygen on Earth during its first three to four billion years. However, it experienced a rise of oxygen levels in its shallow oceans and in the atmosphere during the Paleoproterozoic Era. This event is now called the Great Oxidation Event.
The Great Oxidation Event: Causes and Effects - Profolus
A definitive discussion of the causes and effects of the Great Oxidation Event or the Great Oxygenation Event.
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There is more to AI than chatbots and image generation. The major goals of AI also correspond to the traditional problems AI research intends to solve. Each goal corresponds to a specific subset or subfield of AI.
The Major Goals and Subfields of Artificial Intelligence - Profolus
The major goals of artificial intelligence also correspond to the traditional problems in AI research and specific subfields of AI.
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CATURDAY: Euthanasia was considered the only responsible response to H5N1 in domestic cats. New evidence says otherwise. A researcher documented and demonstrated an effective intervention approach to increase survival rates.
Challenging Euthanasia: Report Notes H5N1 Bird Flu Survival in Cats Possible - Profolus
A new report challenges long-standing euthanasia protocols for H5N1 in cats by documenting cases of survival after effective intervention.
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International mediators pushed through a landmark peace plan and ceasefire for Gaza. But critics warn the deal could reinforce external control without guarantees of accountability and autonomy.
Explaining the 2025 Gaza War Peace Plan and 2025 Gaza Ceasefire - Profolus
A 20-point peace plan proposed by the United States is reshaping the conversation around the future of Gaza.
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CATURDAY: An analysis of over 70 billion U.S. dollars in donations found subtle but consistent differences in giving patterns among cat owners, dog owners, and individuals without pets. Personality traits offering possible explanations.
Study Reveals Cat Owners Donate Slightly More Than Dog Owners - Profolus
Data from 63 million donors shows that cat owners donate more often and to more causes than dog owners.
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The Nintendo Switch 2 features the same hybrid handheld and dockable selling point, but now offers significant hardware upgrades over its predecessor. These include the custom Nvidia Tegra T239 chip, which was manufactured based on the 5nm process node.
Nintendo Switch 2 vs Nintendo Switch 1: Quick Comparison - Profolus
The Nintendo Switch 2 became available on 5 June 2025. This is about eight years after the original Switch was released in 2017.
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