Neural mechanisms underlying flexible learning and decision-making are not fully understood. Using single-cell calcium imaging, authors here found that neurons in orbitofrontal and secondary motor cortex exhibit complementary roles in reward learning, with neurons in the former exerting a sustained role in conditions of uncertainty.

Individuals differ drastically in whether they will cease actions with negative consequences. Using a specially-designed task, we explore the psychological roots for these differences, its stability a...

UNSW researchers uncover why some people persist in harmful behaviours – even when they’ve been shown where they’re going wrong.

Individuals differ in their sensitivity to the adverse consequences of their actions, leading some to persist in maladaptive behaviors. Two pathway...

Using a gamified punishment task, this study identifies specific learning and decision-making deficits that drive robust, consequential differences in choice within an international, general populatio...