Palle Duun Rohde
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palledr.bsky.social
Palle Duun Rohde
@palledr.bsky.social
45 followers 150 following 13 posts
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palledr.bsky.social
🧬 New in PLOS Genetics!
We show how Bayesian Linear Regression models can powerfully fine-map genetic variants underlying complex traits & diseases β€” matching state-of-the-art methods on both simulated & UK Biobank data.
πŸ“„ doi.org/10.1371/journal.pgen.1011783

#Genomics #FineMapping #UKBiobank
Enhanced genetic fine mapping accuracy with Bayesian Linear Regression models in diverse genetic architectures
Author summary Understanding which genetic variants influence complex traits and diseases is essential for gaining biological insight and developing new treatments. However, large-scale genetic studie...
doi.org
August 12, 2025 at 7:04 PM
palledr.bsky.social
🚨 JOB POSSIBILITY 🚨
We launching a new AI-health data initiative and hiring 3 tenure track assistant professors.

I’m seeking one in AI-driven statistical genomics 🧬

πŸ”— www.vacancies.aau.dk/scientific-p...

Please share

#Genomics #StatisticalGenetics #PrecisionMedicine #ComplexTraitGenetics #PopGen
August 11, 2025 at 9:54 AM
palledr.bsky.social
The genetics of pregnancy loss πŸ§¬β¬‡οΈ

www.linkedin.com/posts/palle-...
Proud to share that our research group, Genomic Medicine, has contributed… | Palle Duun Rohde
Proud to share that our research group, Genomic Medicine, has contributed to a recent study investigating the potential mechanisms underlying pregnancy loss. While chromosomal abnormalities are well-...
www.linkedin.com
May 26, 2025 at 7:42 AM
palledr.bsky.social
Today at #eshg2025 in Milan (@eshg.bsky.social) I'm presenting our novel Bayesian polygenic prioritization method, Bayes PoPS.

If you're interested, please visit poster P17.072.A at 13:00

#eshg #genomics #StatisticalGenetics #PrecisionMedicine #ComplexTraitGenetics #eshg2025 #genetics
May 25, 2025 at 7:24 AM
palledr.bsky.social
πŸ”— Full description and application ➑️ www.au.dk/om/stillinge...

βœ‰οΈ Feel free to reach out if you’d like to know more!

#PostdocJobs #StatisticalGenetics #MachineLearning #GenomicMedicine #IntegrativeOmics #SMARTBiomed #QGG #AarhusUniversity #AalborgUniversity #Genomics #ResearchJobs
Postdoctoral Fellowship in Multivariate Statistical Machine Learning and Integrative Genomics - Ledig stilling pΓ₯ Aarhus Universitet
Ledig stilling ved Center for Kvantitativ Genetik og Genomforskning, Aarhus, Aarhus Universitet
www.au.dk
May 14, 2025 at 2:29 PM
palledr.bsky.social
You will:
πŸ” Develop multivariate and Bayesian models for complex trait genetics
🧬 Integrate large-scale genomic and clinical data
🧠 Apply and extend advanced multivariate modeling techniques
πŸ’» Contribute to projects on cardiometabolic and psychiatric conditions
Postdoctoral Fellowship in Multivariate Statistical Machine Learning and Integrative Genomics - Ledig stilling pΓ₯ Aarhus Universitet
Ledig stilling ved Center for Kvantitativ Genetik og Genomforskning, Aarhus, Aarhus Universitet
www.au.dk
May 14, 2025 at 2:29 PM
palledr.bsky.social
🚨 Postdoc Opportunity: Multivariate Statistical Machine Learning & Integrative Genomics!

We’re seeking a highly motivated Postdoctoral Fellow to join the Center for Quantitative Genetics and Genomics, Aarhus University, in close collaboration with me at Genomic Medicine, Aalborg University.
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May 14, 2025 at 2:29 PM
palledr.bsky.social
Awesome shirt 🀩
February 25, 2025 at 10:33 AM
Reposted by Palle Duun Rohde
davidwestergaard.bsky.social
We're hiring!

Make a real difference in women's health at Hvidovre Hospital, Denmark. Use your data skills to analyze large datasets, collaborate with clinicians, and contribute to advancements in reproductive health.

Apply now: www.regionh.dk/job/s%C3%B8g...
January 9, 2025 at 6:45 PM
palledr.bsky.social
2️⃣ BMC Genomics paper: bmcgenomics.biomedcentral.com/articles/10....
Evaluation of Bayesian Linear Regression derived gene set test methods - BMC Genomics
Background Gene set tests can pinpoint genes and biological pathways that exert small to moderate effects on complex diseases like Type 2 Diabetes (T2D). By aggregating genetic markers based on biolog...
bmcgenomics.biomedcentral.com
January 6, 2025 at 9:47 AM
palledr.bsky.social
1️⃣ PLOS Genetics paper: journals.plos.org/plosgenetics...
Evaluation of Bayesian Linear Regression models for gene set prioritization in complex diseases
Author summary Our study introduces a new method for prioritizing biological pathways in complex diseases using Bayesian Linear Regression (BLR) models. Genome-wide association studies (GWAS) have sig...
journals.plos.org
January 6, 2025 at 9:47 AM
palledr.bsky.social
πŸ”¬ Both simulation studies and real data confirm increased statistical power - particularly when analyzing multiple traits together. Better tools = better understanding of disease genetics! #Genetics #Bioinformatics #Statistics
January 6, 2025 at 9:47 AM
palledr.bsky.social
🧬 Excited to share our two recent papers in PLOS Genetics πŸ‘‡and BMC Genomics πŸ‘‡πŸ‘‡ on improving genetic pathway analysis! We've developed a Bayesian approach that outperforms current methods in identifying disease-related gene sets, especially for complex conditions like T2D.
January 6, 2025 at 9:47 AM
palledr.bsky.social
Nice. Please also consider our two R packages for large-scale analysis of complex trait;

qgg - psoerensen.github.io/qgg/ [PMID: 31883004 & PMID: 37882742]

gact - psoerensen.github.io/gact/
Statistical Tools for Quantitative Genetic Analyses
Provides an infrastructure for efficient processing of large-scale genetic and phenotypic data including core functions for: 1) fitting linear mixed models, 2) constructing marker-based genomic relati...
psoerensen.github.io
November 30, 2024 at 8:14 PM