tert-Butanesulfinyl imines can be used for asymmetric syntheses of β-substituted as well as β,β- and α,β-disubstituted β-amino acids
tert-Butanesulfinyl imines can be used for asymmetric syntheses of β-substituted as well as β,β- and α,β-disubstituted β-amino acids
The combination of Ph3P/ICH2CH2I promotes a dehydroxylative sulfonylation of benzylic and allylic alcohols with a variety of sulfinates
The combination of Ph3P/ICH2CH2I promotes a dehydroxylative sulfonylation of benzylic and allylic alcohols with a variety of sulfinates
A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate
A formal (3+2)-cycloaddition of donor-acceptor cyclopropanes and ammonium thiocyanate
A useful catalyst system for the Heck coupling of aryl chlorides has been developed. The choice of ligand is critical for activity.
A useful catalyst system for the Heck coupling of aryl chlorides has been developed. The choice of ligand is critical for activity.
A catalyst-free synthesis of phosphinic amides from hydroxyl amines and chlorophosphines
A catalyst-free synthesis of phosphinic amides from hydroxyl amines and chlorophosphines
N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in KOtBu/DMSO solution to provide 2,3,5-triarylpyrrolines
N-Benzyl ketimines undergo [3 + 2] cycloaddition with arylacetylenes in KOtBu/DMSO solution to provide 2,3,5-triarylpyrrolines
Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride
Aldimines undergo nucleophilic addition with diethyl phosphite in the presence of a catalytic amount of zirconium tetrachloride
Boronic acid catalyzed one-pot reductions of quinolines with Hantzsch ester followed by N-arylations via external base-free Chan-Evans-Lam coupling
Boronic acid catalyzed one-pot reductions of quinolines with Hantzsch ester followed by N-arylations via external base-free Chan-Evans-Lam coupling
Chiral bis(oxazoline)alkynylphosphine ligands can be used in Rh-catalyzed highly regio- and enantioselective allylic amination reactions
Chiral bis(oxazoline)alkynylphosphine ligands can be used in Rh-catalyzed highly regio- and enantioselective allylic amination reactions
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3
Indole and 2-methylindole undergo conjugate addition with electron-deficient olefins in the presence of a catalytic amount of InCl3
Eosin Y catalyzes an efficient photochemical aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones
Eosin Y catalyzes an efficient photochemical aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones
A visible light-promoted divergent cycloaddition of α-diazo esters to hexahydro-1,3,5-triazines provides a series of aziridines and imidazolidines
A visible light-promoted divergent cycloaddition of α-diazo esters to hexahydro-1,3,5-triazines provides a series of aziridines and imidazolidines
A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed.
A practical method for large-scale acetylation of 1° and 2° alcohols as well as diols has been developed.
A Pd-catalyzed enantioselective aminochlorination of alkenes provides diverse 3-chloropiperidines via a 6-endo cyclization
A Pd-catalyzed enantioselective aminochlorination of alkenes provides diverse 3-chloropiperidines via a 6-endo cyclization
A solvent-free, TfOH-promoted decyanative cyclization enables the synthesis of 2,1-benzisoxazoles in good yields.
A solvent-free, TfOH-promoted decyanative cyclization enables the synthesis of 2,1-benzisoxazoles in good yields.
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A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.
A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.
An enantioselective catalytic Suzuki-Miyaura reaction of meso 1,2-diborylcycloalkanes
An enantioselective catalytic Suzuki-Miyaura reaction of meso 1,2-diborylcycloalkanes
Lithium perchlorate efficiently catalyzes the Biginelli three-component condensation reaction of aldehydes, β-keto esters and urea in refluxing acetonitrile
Lithium perchlorate efficiently catalyzes the Biginelli three-component condensation reaction of aldehydes, β-keto esters and urea in refluxing acetonitrile
A trifluoroacetic acid-promoted amino-Claisen rearrangement provides highly functionalized indoles.
A trifluoroacetic acid-promoted amino-Claisen rearrangement provides highly functionalized indoles.
A Cu-catalyzed propargylic amination of amines with propargylic cyclic carbonates provides chiral acyclic α-quaternary α-amino ketones.
A Cu-catalyzed propargylic amination of amines with propargylic cyclic carbonates provides chiral acyclic α-quaternary α-amino ketones.
A cross-coupling reaction of homoallyl alcohols with aldehydes in the presence of Amberlyst-15 yields 4-hydroxy-2,6-disubstituted tetrahydropyrans
A cross-coupling reaction of homoallyl alcohols with aldehydes in the presence of Amberlyst-15 yields 4-hydroxy-2,6-disubstituted tetrahydropyrans
A simple and mild direct chloride/fluoride exchange for the synthesis of sulfonyl fluorides
A simple and mild direct chloride/fluoride exchange for the synthesis of sulfonyl fluorides
A transition-metal-free α-cyanation of easy accessible N-fluorotosylsulfonamides
A transition-metal-free α-cyanation of easy accessible N-fluorotosylsulfonamides
Cerium chloride efficiently catalyses the ring opening of epoxides with aromatic amines to generate β-amino alcohols.
Cerium chloride efficiently catalyses the ring opening of epoxides with aromatic amines to generate β-amino alcohols.