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✅ FDA approves lisocabtagene maraleucel (Breyanzi) for adults with R/R marginal zone lymphoma after ≥2 prior systemic therapies.
📌 Approval supported by TRANSCEND FL-MZL Cohort trial, delivering a new CAR-T option for patients with limited treatment choices.
✅ FDA approves lisocabtagene maraleucel (Breyanzi) for adults with R/R marginal zone lymphoma after ≥2 prior systemic therapies.
📌 Approval supported by TRANSCEND FL-MZL Cohort trial, delivering a new CAR-T option for patients with limited treatment choices.
🧬 ctDNA may guide adjuvant decisions in Stage III Colon Cancer.
➡️ Post-hoc analysis from CALGB/SWOG 80702 suggests circulating tumor DNA status could help identify patients who may benefit from adding celecoxib to standard chemotherapy.
🧬 ctDNA may guide adjuvant decisions in Stage III Colon Cancer.
➡️ Post-hoc analysis from CALGB/SWOG 80702 suggests circulating tumor DNA status could help identify patients who may benefit from adding celecoxib to standard chemotherapy.
➡️ Adding atezolizumab to bevacizumab + non-platinum chemo did not significantly improve OS or PFS in platinum-ineligible recurrent ovarian cancer.
📌 Safety profile remained consistent with known data.
➡️ Adding atezolizumab to bevacizumab + non-platinum chemo did not significantly improve OS or PFS in platinum-ineligible recurrent ovarian cancer.
📌 Safety profile remained consistent with known data.
✅ U.S. FDA expands approval for Lilly’s Jaypirca (pirtobrutinib) now for adults with relapsed/refractory CLL/SLL after covalent BTKi therapy.
📌 Backed by Phase 3 BRUIN CLL-321 results, broadening access for more patients per NCCN guidance.
✅ U.S. FDA expands approval for Lilly’s Jaypirca (pirtobrutinib) now for adults with relapsed/refractory CLL/SLL after covalent BTKi therapy.
📌 Backed by Phase 3 BRUIN CLL-321 results, broadening access for more patients per NCCN guidance.
A fast, focused way to test your knowledge on risk factors, staging, biomarkers + frontline therapy.
Plus explore other quizzes like Hodgkin’s Lymphoma & RCC.
Boost your oncology knowledge → buff.ly/DndcrbP
#Oncology #OvarianCancer
A fast, focused way to test your knowledge on risk factors, staging, biomarkers + frontline therapy.
Plus explore other quizzes like Hodgkin’s Lymphoma & RCC.
Boost your oncology knowledge → buff.ly/DndcrbP
#Oncology #OvarianCancer
✅ FDA Approves IsoPSA® — a Novel Blood-Based Test for Prostate Cancer Detection
➡️ IsoPSA evaluates prostate cancer–specific structural variants of the PSA protein, helping identify high-grade prostate cancer with greater precision.
✅ FDA Approves IsoPSA® — a Novel Blood-Based Test for Prostate Cancer Detection
➡️ IsoPSA evaluates prostate cancer–specific structural variants of the PSA protein, helping identify high-grade prostate cancer with greater precision.
🔬 STELLAR Phase III Trial Update:
A randomized, open-label study evaluating Eflornithine + Lomustine vs. Lomustine alone in patients with recurrent Grade 3 astrocytoma.
✨ Advancing understanding of treatment options in recurrent gliomas.
🔗 Read more: bit.ly/ONCOnews02D-1
🔬 STELLAR Phase III Trial Update:
A randomized, open-label study evaluating Eflornithine + Lomustine vs. Lomustine alone in patients with recurrent Grade 3 astrocytoma.
✨ Advancing understanding of treatment options in recurrent gliomas.
🔗 Read more: bit.ly/ONCOnews02D-1
#mCRPC #ProstateCancer #OncologyTools #CancerCare #ClinicalOncology #DigitalHealth #OncologyApp #AdvancedProstateCancer #oncologytools
#mCRPC #ProstateCancer #OncologyTools #CancerCare #ClinicalOncology #DigitalHealth #OncologyApp #AdvancedProstateCancer #oncologytools
✅ Imfinzi (durvalumab) becomes the first perioperative immunotherapy approved in the US for early gastric & GEJ cancers.
Phase III MATTERHORN data show strong outcomes:
🔹 29% lower risk of progression, recurrence or reduced OS.
🔹 22% lower risk of reduced OS vs. standard chemo
✅ Imfinzi (durvalumab) becomes the first perioperative immunotherapy approved in the US for early gastric & GEJ cancers.
Phase III MATTERHORN data show strong outcomes:
🔹 29% lower risk of progression, recurrence or reduced OS.
🔹 22% lower risk of reduced OS vs. standard chemo
🔔 PharmaEssentia, announces that positive results from its pivotal Phase 3 SURPASS-ET clinical trial have been published in The Lancet Haematology.
➡️ The SURPASS-ET compared ropeginterferon alfa-2b vs anagrelide in hydroxyurea-resistant/intolerant ET with leukocytosis.
🔔 PharmaEssentia, announces that positive results from its pivotal Phase 3 SURPASS-ET clinical trial have been published in The Lancet Haematology.
➡️ The SURPASS-ET compared ropeginterferon alfa-2b vs anagrelide in hydroxyurea-resistant/intolerant ET with leukocytosis.
🔔 The EC approves expanded use of Breyanzi® (lisocabtagene maraleucel; liso-cel) for R/R Mantle Cell Lymphoma (MCL).
🧬 In the TRANSCEND MCL trial, 82.7% of patients responded, with 71.6% achieving a complete response, and over 50% maintaining response at 24 months.
🔔 The EC approves expanded use of Breyanzi® (lisocabtagene maraleucel; liso-cel) for R/R Mantle Cell Lymphoma (MCL).
🧬 In the TRANSCEND MCL trial, 82.7% of patients responded, with 71.6% achieving a complete response, and over 50% maintaining response at 24 months.
🔔 The FDA has approved pembrolizumab in combination with enfortumab vedotin-ejfv as a neoadjuvant + adjuvant treatment for adults with MIBC who are ineligible for cisplatin.
🎯 The major efficacy outcome measure was EFS assessed by blinded independent central review.
🔔 The FDA has approved pembrolizumab in combination with enfortumab vedotin-ejfv as a neoadjuvant + adjuvant treatment for adults with MIBC who are ineligible for cisplatin.
🎯 The major efficacy outcome measure was EFS assessed by blinded independent central review.
🔔 FDA grants accelerated approval to Sevabertinib for adults with metastatic non-squamous NSCLC harboring HER2 TKD activating mutations after prior systemic therapy.
➡️ FDA also clears the Oncomine Dx Target Test as a companion diagnostic to identify eligible patients.
🔔 FDA grants accelerated approval to Sevabertinib for adults with metastatic non-squamous NSCLC harboring HER2 TKD activating mutations after prior systemic therapy.
➡️ FDA also clears the Oncomine Dx Target Test as a companion diagnostic to identify eligible patients.
🔔 The FDA has granted full approval to daratumumab and hyaluronidase-fihj plus VCd for newly diagnosed light chain (AL) amyloidosis, converting its 2021 accelerated approval to traditional approval.
✅ This decision is supported by results from the ANDROMEDA Phase 3 trial.
🔔 The FDA has granted full approval to daratumumab and hyaluronidase-fihj plus VCd for newly diagnosed light chain (AL) amyloidosis, converting its 2021 accelerated approval to traditional approval.
✅ This decision is supported by results from the ANDROMEDA Phase 3 trial.
📢 FDA approves selumetinib(KOSELUGO, AstraZeneca Pharmaceuticals LP) for adults with NF1 experiencing symptomatic, inoperable plexiform neurofibromas.
🔹FDA previously approved selumetinib capsules and granules for pediatric patients 1 year of age and older for this indication.
📢 FDA approves selumetinib(KOSELUGO, AstraZeneca Pharmaceuticals LP) for adults with NF1 experiencing symptomatic, inoperable plexiform neurofibromas.
🔹FDA previously approved selumetinib capsules and granules for pediatric patients 1 year of age and older for this indication.
✅ EU approves Libtayo® (cemiplimab) as the first immunotherapy for adjuvant treatment of CSCC at high risk of recurrence after surgery and radiation.
📉 Phase 3 C-POST trial: Significant improvement in disease-free survival with a 68% reduction in recurrence.
✅ EU approves Libtayo® (cemiplimab) as the first immunotherapy for adjuvant treatment of CSCC at high risk of recurrence after surgery and radiation.
📉 Phase 3 C-POST trial: Significant improvement in disease-free survival with a 68% reduction in recurrence.
✅ FDA grants full approval to Amgen's IMDELLTRA® (tarlatamab-dlle) in extensive stage small cell lung cancer (ES-SCLC).
🎯 Phase 3 DeLLphi-304 shows 40% reduction in risk of death vs chemo.
🔗 Read more: bit.ly/ONCOnews20N3
#ONCOnews #OncoAlert #OncEd #Oncology #CancerUpdates
✅ FDA grants full approval to Amgen's IMDELLTRA® (tarlatamab-dlle) in extensive stage small cell lung cancer (ES-SCLC).
🎯 Phase 3 DeLLphi-304 shows 40% reduction in risk of death vs chemo.
🔗 Read more: bit.ly/ONCOnews20N3
#ONCOnews #OncoAlert #OncEd #Oncology #CancerUpdates
The CTCAE criteria are designed to standardise adverse event reporting in oncology research and practice.
#ONCOassist #CTCAEv6 #ToxicityGrading #AdverseEvents #OncologyTools #DigitalHealth #CancerCare #ClinicalOncology #OncologyApp
The CTCAE criteria are designed to standardise adverse event reporting in oncology research and practice.
#ONCOassist #CTCAEv6 #ToxicityGrading #AdverseEvents #OncologyTools #DigitalHealth #CancerCare #ClinicalOncology #OncologyApp
🆕 EU approves Roche’s Lunsumio® (mosunetuzumab) subcutaneous (SC) for relapsed/refractory follicular lymphoma — offering durable responses even in later-line disease.
⏱️ New SC option cuts administration time to ~1 minute, supporting greater treatment flexibility for patients.
🆕 EU approves Roche’s Lunsumio® (mosunetuzumab) subcutaneous (SC) for relapsed/refractory follicular lymphoma — offering durable responses even in later-line disease.
⏱️ New SC option cuts administration time to ~1 minute, supporting greater treatment flexibility for patients.
🔔 The European Commission has approved subcutaneous KEYTRUDA® (pembrolizumab) for all adult EU-approved indications — becoming the first and only subcutaneous immune checkpoint inhibitor in Europe.
🔗 Read more: bit.ly/ONCOnews20N-1
#ONCOnews #OncoAlert #OncEd #Oncology
🔔 The European Commission has approved subcutaneous KEYTRUDA® (pembrolizumab) for all adult EU-approved indications — becoming the first and only subcutaneous immune checkpoint inhibitor in Europe.
🔗 Read more: bit.ly/ONCOnews20N-1
#ONCOnews #OncoAlert #OncEd #Oncology
🔹Stay up to date with the latest adverse event standards.
🔹Search and grade adverse events instantly.
🔹Streamline your documentation.
🔹Improve communication and safety in daily oncology practice.
➡️ CTCAE v4 & v5 are still available in the app.
🔹Stay up to date with the latest adverse event standards.
🔹Search and grade adverse events instantly.
🔹Streamline your documentation.
🔹Improve communication and safety in daily oncology practice.
➡️ CTCAE v4 & v5 are still available in the app.
✅ FDA approves EPKINLY® (epcoritamab-bysp) in combination with Rituximab and Lenalidomide for relapsed/refractory follicular lymphoma!
💥 First-ever bispecific antibody combination approved, delivering superior PFS & response rates in Phase 3 EPCORE FL-1 study.
✅ FDA approves EPKINLY® (epcoritamab-bysp) in combination with Rituximab and Lenalidomide for relapsed/refractory follicular lymphoma!
💥 First-ever bispecific antibody combination approved, delivering superior PFS & response rates in Phase 3 EPCORE FL-1 study.
📣 Phase 3 results show ZIIHERA® (zanidatamab) delivers strong efficacy as a leading HER2-targeted therapy.
✅ Its combination with TEVIMBRA® (tislelizumab) + chemotherapy is emerging as a new first-line standard of care in HER2-positive gastroesophageal cancer.
📣 Phase 3 results show ZIIHERA® (zanidatamab) delivers strong efficacy as a leading HER2-targeted therapy.
✅ Its combination with TEVIMBRA® (tislelizumab) + chemotherapy is emerging as a new first-line standard of care in HER2-positive gastroesophageal cancer.
💊 Roche’s giredestrant becomes the first oral SERD to show superior iDFS vs standard endocrine therapy.
📈 A potential new standard of care emerges - lidERA trial delivers a second Phase III success after evERA trial.
🔗 Read more: bit.ly/ONCOnews18N-1
💊 Roche’s giredestrant becomes the first oral SERD to show superior iDFS vs standard endocrine therapy.
📈 A potential new standard of care emerges - lidERA trial delivers a second Phase III success after evERA trial.
🔗 Read more: bit.ly/ONCOnews18N-1
✅ FDA Approves First Ever Perjeta Biosimilar!
📢 Poherdy (pertuzumab-dpzb, Shanghai Henlius Biologics Co. Ltd.) is now approved as an interchangeable biosimilar to Perjeta(pertuzumab, Genentech Inc.) for HER2+ breast cancer across metastatic, neoadjuvant, and adjuvant settings.
✅ FDA Approves First Ever Perjeta Biosimilar!
📢 Poherdy (pertuzumab-dpzb, Shanghai Henlius Biologics Co. Ltd.) is now approved as an interchangeable biosimilar to Perjeta(pertuzumab, Genentech Inc.) for HER2+ breast cancer across metastatic, neoadjuvant, and adjuvant settings.