Olivia Davis
banner
oliviadavis.bsky.social
Olivia Davis
@oliviadavis.bsky.social
Interested in the neuroanatomy of pain and all things spinal cord.
Reposted by Olivia Davis
The latest work from our PRECISION Human Pain Center project is now up on @biorxivpreprint.bsky.social led by Katherin Gabriel and @oliviadavis.bsky.social with a huge contribution from @allanhpool.bsky.social's lab and, of course, the Southwest Transplant Alliance: www.biorxiv.org/content/10.1...
A molecular map of the human spinal dorsal and ventral horn defines arrangement of neuronal types and glial sex differences
The spinal cord is the gateway for sensory information from the body as it ascends to the brain, as well as a major motor output center of the nervous system. It is also a key location for sensory-mot...
www.biorxiv.org
November 1, 2025 at 12:10 PM
Thrilled to share our latest preprint using single nuq sequencing and Xenium to define neuron organisation and sex differences in glia within human spinal cord. Truly a collaborative effort, with a big shoutout to Katherin Gabriel and @tedpricethepainguy.bsky.social

www.biorxiv.org/content/10.1...
A molecular map of the human spinal dorsal and ventral horn defines arrangement of neuronal types and glial sex differences
The spinal cord is the gateway for sensory information from the body as it ascends to the brain, as well as a major motor output center of the nervous system. It is also a key location for sensory-mot...
www.biorxiv.org
November 1, 2025 at 10:46 AM
Sharing a figure from our recent paper showing excitatory synapses in the human spinal dorsal horn. I’ll never get over the awe of seeing these tiny dots, which underly such an important part of the human experience!
@tedpricethepainguy.bsky.social

onlinelibrary.wiley.com/doi/10.1002/...
October 23, 2025 at 7:59 PM
Reposted by Olivia Davis
Our paper showing decreased KCC2 expression in the human spinal cord in people who died with a history of neuropathic pain is now published in PAIN: journals.lww.com/pain/abstrac... Great work from @oliviadavis.bsky.social and the teams of the De Koninck and Hildebrand labs. ❤️ 🇨🇦 collabs!
Decreased KCC2 expression in the human spinal dorsal horn... : PAIN
date there is no evidence supporting or opposing this hypothesis in humans. Here, we demonstrate that KCC2 expression is decreased in superficial dorsal horn neurons of organ donors who died with a do...
journals.lww.com
July 22, 2025 at 11:01 PM
Highly, highly recommend working with Andy and the Spinal Cord Group!
July 3, 2025 at 8:23 PM
Reposted by Olivia Davis
Glutamatergic and GABAergic synapses in the human spinal dorsal horn revealed with immunohistochemistry https://www.biorxiv.org/content/10.1101/2025.04.07.647666v1
April 9, 2025 at 5:15 PM
Reposted by Olivia Davis
Very excited to share our new preprint: "Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use" led by @oliviadavis.bsky.social and Samuel Ferland, a collab between us, Yves De Koninck and Mike Hildebrand labs www.biorxiv.org/content/10.1...
Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use
Loss of GABAergic and glycinergic inhibitory efficacy in the spinal dorsal horn is associated with neuropathic pain and opioid-induced hyperalgesia in rodent models. Downregulation of the KCC2 chlorid...
www.biorxiv.org
January 20, 2025 at 2:05 PM