Myofin Research Group
@myofinlab.bsky.social
🧬 We research the various aspects of hereditary myopathies and muscular dystrophies
📍 @folkhalsanresearch.bsky.social , Helsinki, Finland
https://linktr.ee/myofin
📍 @folkhalsanresearch.bsky.social , Helsinki, Finland
https://linktr.ee/myofin
Pinned
We are the Myofin Research Group, part of the Genetics Research Program at Folkhälsan Research Center, Helsinki, Finland. (1/6)
Check out Peter's discussion with Sarah Foye, President and Founder of Team Titin ! 💪 The interview was filmed as part of the 2025 Scientific and Family Conference hosted by Cure CMD, A Foundation Building Strength for Nemaline Myopathy and Team Titin.
Dr. Peter Hackman, PhD Team Titin Interview
YouTube video by Team Titin
www.youtube.com
November 28, 2025 at 9:27 AM
Check out Peter's discussion with Sarah Foye, President and Founder of Team Titin ! 💪 The interview was filmed as part of the 2025 Scientific and Family Conference hosted by Cure CMD, A Foundation Building Strength for Nemaline Myopathy and Team Titin.
🚨Publication alert!🚨
First author Veronica's summary of the article:
"This study examined six individuals from five unrelated families who carried truncating variants in exon 363 of the TTN gene, all presenting with recessive titinopathies." (1/4)
First author Veronica's summary of the article:
"This study examined six individuals from five unrelated families who carried truncating variants in exon 363 of the TTN gene, all presenting with recessive titinopathies." (1/4)
Novel Mutations in Titin Exon 363 With Different Phenotypes Including a Founder Mutation in Eastern Europe
In six patients from five families, we identified two novel exon 363 pathogenic variants causing recessive titinopathies. Patients with a recurrent Eastern European founder variant presented with juv....
onlinelibrary.wiley.com
November 27, 2025 at 1:48 PM
🚨Publication alert!🚨
First author Veronica's summary of the article:
"This study examined six individuals from five unrelated families who carried truncating variants in exon 363 of the TTN gene, all presenting with recessive titinopathies." (1/4)
First author Veronica's summary of the article:
"This study examined six individuals from five unrelated families who carried truncating variants in exon 363 of the TTN gene, all presenting with recessive titinopathies." (1/4)
🚨Publication alert!🚨
First author Johanna's summary of the article:
"GNE myopathy is a rare autosomal recessive skeletal muscle disorder. It typically starts in the lower legs, gradually progressing to other muscle groups." (1/2)
First author Johanna's summary of the article:
"GNE myopathy is a rare autosomal recessive skeletal muscle disorder. It typically starts in the lower legs, gradually progressing to other muscle groups." (1/2)
Novel missense variants associated with GNE myopathy
Biallelic variants in the GNE gene, which encodes UDP-N-Acetylglucosamine 2-epimerase/N-Acetylmannosamine
Kinase, cause an autosomal recessive GNE myopathy (GNEM), characterized by progressive
muscle ...
www.nmd-journal.com
November 24, 2025 at 1:18 PM
🚨Publication alert!🚨
First author Johanna's summary of the article:
"GNE myopathy is a rare autosomal recessive skeletal muscle disorder. It typically starts in the lower legs, gradually progressing to other muscle groups." (1/2)
First author Johanna's summary of the article:
"GNE myopathy is a rare autosomal recessive skeletal muscle disorder. It typically starts in the lower legs, gradually progressing to other muscle groups." (1/2)
🚨Publication alert!🚨
First author Veronica's summary of the article:
"The study focused on finding a robust and reproducible method to differentiate the C2C12 murine myoblast into mature and functional myotubes in a 2D culture system." (1/3)
First author Veronica's summary of the article:
"The study focused on finding a robust and reproducible method to differentiate the C2C12 murine myoblast into mature and functional myotubes in a 2D culture system." (1/3)
Optimizing 2D in vitro differentiation conditions for C2C12 murine myoblasts on gelatin hydrogel - Journal of Muscle Research and Cell Motility
Optimizing in vitro differentiation protocols for skeletal muscle cells is essential for producing mature, functional myotubes suitable for disease modeling and therapeutic screening. While C2C12 muri...
link.springer.com
November 20, 2025 at 6:35 AM
🚨Publication alert!🚨
First author Veronica's summary of the article:
"The study focused on finding a robust and reproducible method to differentiate the C2C12 murine myoblast into mature and functional myotubes in a 2D culture system." (1/3)
First author Veronica's summary of the article:
"The study focused on finding a robust and reproducible method to differentiate the C2C12 murine myoblast into mature and functional myotubes in a 2D culture system." (1/3)
Meet our group members!🧬
▫️Maria Francesca Di Feo (MD), Clinical Geneticist & Doctoral Researcher
Maria Francesca (she/her) graduated in Medicine in 2020 from the University of Modena & Reggio Emilia and completed her specialization in Clinical Genetics at the University of Genova in 2025. (1/7)
▫️Maria Francesca Di Feo (MD), Clinical Geneticist & Doctoral Researcher
Maria Francesca (she/her) graduated in Medicine in 2020 from the University of Modena & Reggio Emilia and completed her specialization in Clinical Genetics at the University of Genova in 2025. (1/7)
November 12, 2025 at 6:15 AM
Meet our group members!🧬
▫️Maria Francesca Di Feo (MD), Clinical Geneticist & Doctoral Researcher
Maria Francesca (she/her) graduated in Medicine in 2020 from the University of Modena & Reggio Emilia and completed her specialization in Clinical Genetics at the University of Genova in 2025. (1/7)
▫️Maria Francesca Di Feo (MD), Clinical Geneticist & Doctoral Researcher
Maria Francesca (she/her) graduated in Medicine in 2020 from the University of Modena & Reggio Emilia and completed her specialization in Clinical Genetics at the University of Genova in 2025. (1/7)
Happy Halloween! 🎃👻🔮 The single muscle fibres won the ”Best Group Costume” prize at @folkhalsanresearch.bsky.social 🏆
October 30, 2025 at 2:44 PM
Happy Halloween! 🎃👻🔮 The single muscle fibres won the ”Best Group Costume” prize at @folkhalsanresearch.bsky.social 🏆
Check out our recap videos from #EMC2025 and #WMS2025 on our Instagram 📹 :
European Muscle Conference (www.instagram.com/reel/DPTJFxc...)
World Muscle Society Congress (www.instagram.com/reel/DQOT_LV...)
European Muscle Conference (www.instagram.com/reel/DPTJFxc...)
World Muscle Society Congress (www.instagram.com/reel/DQOT_LV...)
October 25, 2025 at 8:18 AM
Check out our recap videos from #EMC2025 and #WMS2025 on our Instagram 📹 :
European Muscle Conference (www.instagram.com/reel/DPTJFxc...)
World Muscle Society Congress (www.instagram.com/reel/DQOT_LV...)
European Muscle Conference (www.instagram.com/reel/DPTJFxc...)
World Muscle Society Congress (www.instagram.com/reel/DQOT_LV...)
🚨Publication alert!🚨
Marco’s summary of the article:
”New multicenter MRI study shows that in autosomal dominant titinopathies, Hereditary Myopathy with Early Respiratory Failure involves broad, severe fat replacement (esp. in semitendinosus, gluteus minimus and obturator externus), … (1/2)
Marco’s summary of the article:
”New multicenter MRI study shows that in autosomal dominant titinopathies, Hereditary Myopathy with Early Respiratory Failure involves broad, severe fat replacement (esp. in semitendinosus, gluteus minimus and obturator externus), … (1/2)
Different Lower Limb Muscle MRI Patterns in Autosomal Dominant Titinopathies
Background and Purpose
Titin is critical for sarcomere structure and function, and mutations in this gene cause titinopathies, a group of neuromuscular disorders. Muscle MRI is a key tool for diagno.....
onlinelibrary.wiley.com
October 17, 2025 at 8:36 AM
🚨Publication alert!🚨
Marco’s summary of the article:
”New multicenter MRI study shows that in autosomal dominant titinopathies, Hereditary Myopathy with Early Respiratory Failure involves broad, severe fat replacement (esp. in semitendinosus, gluteus minimus and obturator externus), … (1/2)
Marco’s summary of the article:
”New multicenter MRI study shows that in autosomal dominant titinopathies, Hereditary Myopathy with Early Respiratory Failure involves broad, severe fat replacement (esp. in semitendinosus, gluteus minimus and obturator externus), … (1/2)
Reposted by Myofin Research Group
Thank you @worldmusclesociety.org for an amazing meeting #WMS2025 💪🔬 The Finnish team thoroughly enjoyed the science and the networking! @myofinlab.bsky.social @folkhalsanresearch.bsky.social
October 12, 2025 at 7:37 AM
Thank you @worldmusclesociety.org for an amazing meeting #WMS2025 💪🔬 The Finnish team thoroughly enjoyed the science and the networking! @myofinlab.bsky.social @folkhalsanresearch.bsky.social
Reposted by Myofin Research Group
October 12, 2025 at 8:11 AM
October 11, 2025 at 12:34 PM
Reposted by Myofin Research Group
Great times with the Myofin team (@myofinlab.bsky.social) at #WMS2025 In Vienna !😂
October 11, 2025 at 8:41 AM
Great times with the Myofin team (@myofinlab.bsky.social) at #WMS2025 In Vienna !😂
@jaakkosarparanta.bsky.social presenting in the poster highlights session! 👏
#WMS2025
@worldmusclesociety.org
#WMS2025
@worldmusclesociety.org
October 11, 2025 at 8:20 AM
@jaakkosarparanta.bsky.social presenting in the poster highlights session! 👏
#WMS2025
@worldmusclesociety.org
#WMS2025
@worldmusclesociety.org
Reposted by Myofin Research Group
So many "MyoFinns" in the #WMS2025 meeting this year! 💪🔬 Representing @myofinlab.bsky.social @folkhalsanresearch.bsky.social
October 10, 2025 at 7:49 AM
So many "MyoFinns" in the #WMS2025 meeting this year! 💪🔬 Representing @myofinlab.bsky.social @folkhalsanresearch.bsky.social
Our team is excited to connect - come find us at the @worldmusclesociety.org congress. 🇦🇹 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#WMS2025
#WMS2025
October 6, 2025 at 7:12 PM
Our team is excited to connect - come find us at the @worldmusclesociety.org congress. 🇦🇹 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#WMS2025
#WMS2025
During the week in between EMC and WMS, Jenni and Fanny visited the de Winter, Ottenheijm and Kirby labs at the Department of Physiology at Amsterdam UMC for an intro to single fibre mechanics and some interesting imaging techniques. 🇳🇱🔬 (1/2)
October 5, 2025 at 4:39 PM
During the week in between EMC and WMS, Jenni and Fanny visited the de Winter, Ottenheijm and Kirby labs at the Department of Physiology at Amsterdam UMC for an intro to single fibre mechanics and some interesting imaging techniques. 🇳🇱🔬 (1/2)
Reposted by Myofin Research Group
Two years from today #Helsinki and #Finlandiahall will welcome #WMS2027, the annual congress of @worldmusclesociety.org. Save the date!
September 28, 2025 at 3:54 PM
Two years from today #Helsinki and #Finlandiahall will welcome #WMS2027, the annual congress of @worldmusclesociety.org. Save the date!
Greetings from the opening ceremony of the European Muscle Conference 2025! 🇳🇱 #EMC2025 #EuropeanMuscleConference
September 20, 2025 at 6:56 PM
Greetings from the opening ceremony of the European Muscle Conference 2025! 🇳🇱 #EMC2025 #EuropeanMuscleConference
Our team is excited to connect - come find Jenni, Jaakko and Fanny at the European Muscle Conference. 🇳🇱 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#EMC2025 #EuropeanMuscleConference
#EMC2025 #EuropeanMuscleConference
September 19, 2025 at 3:46 PM
Our team is excited to connect - come find Jenni, Jaakko and Fanny at the European Muscle Conference. 🇳🇱 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
#EMC2025 #EuropeanMuscleConference
#EMC2025 #EuropeanMuscleConference
Myofin ”Summer” meeting in Nuuksio 🧬💡🌲. A couple of days filled with insightful scientific talks and interactive discussions on current and upcoming projects! On Wednesday evening it was sauna time and we grilled sausage over the fire 🧖🔥🪵.
September 18, 2025 at 6:18 PM
Myofin ”Summer” meeting in Nuuksio 🧬💡🌲. A couple of days filled with insightful scientific talks and interactive discussions on current and upcoming projects! On Wednesday evening it was sauna time and we grilled sausage over the fire 🧖🔥🪵.
Our team is excited to connect - come find Johanna at the Norwegian Conference for Hereditary Neuromuscular Disorders. 🇳🇴 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
September 4, 2025 at 4:58 PM
Our team is excited to connect - come find Johanna at the Norwegian Conference for Hereditary Neuromuscular Disorders. 🇳🇴 Let’s talk science, collaboration, and future ideas! 🧬🤝💡
Reposted by Myofin Research Group
Registration for the @myofinlab.bsky.social - organized course, ILS144: "Genetic and genomic technologies in health care" is open. Link: tinyurl.com/43n2ydwu @folkhalsanresearch.bsky.social @helsinki.fi
Studies
tinyurl.com
August 7, 2025 at 9:12 AM
Registration for the @myofinlab.bsky.social - organized course, ILS144: "Genetic and genomic technologies in health care" is open. Link: tinyurl.com/43n2ydwu @folkhalsanresearch.bsky.social @helsinki.fi
Reposted by Myofin Research Group
When you get a feeling that someone's watching.. Our summer student making great progress with our AI analyses ❤️💪🔬 #muscleresearch #raredisease #myoblue @myofinlab.bsky.social @folkhalsanresearch.bsky.social
July 11, 2025 at 7:20 AM
When you get a feeling that someone's watching.. Our summer student making great progress with our AI analyses ❤️💪🔬 #muscleresearch #raredisease #myoblue @myofinlab.bsky.social @folkhalsanresearch.bsky.social
Reposted by Myofin Research Group
So many reasons to celebrate! And these guys are always up for some bubbles 🎉🥂💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social
July 5, 2025 at 11:41 AM
So many reasons to celebrate! And these guys are always up for some bubbles 🎉🥂💪🔬 @myofinlab.bsky.social @folkhalsanresearch.bsky.social