Monosov Lab
@monosovlab.bsky.social
Studying the algorithms and biological circuits of decision making, motivation, emotion, and learning at Johns Hopkins
Reposted by Monosov Lab
Nature research paper: Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing
go.nature.com/4oX2rmq
go.nature.com/4oX2rmq
Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing - Nature
How the mouse frontal cortex and striatum interact to implement integrator dynamics controlling movement timing is explored.
go.nature.com
November 24, 2025 at 9:19 AM
Nature research paper: Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing
go.nature.com/4oX2rmq
go.nature.com/4oX2rmq
How do non-neuronal CNS cells called astrocytes contribute to cognition & computation?
See our preprint
Headed by my students Julia Pai and Fatih Sogukpinar, also working with Hiratani, Pignatelli, Papouin, Frank, and Ching labs. This was a huge effort
www.biorxiv.org/content/10.1...
See our preprint
Headed by my students Julia Pai and Fatih Sogukpinar, also working with Hiratani, Pignatelli, Papouin, Frank, and Ching labs. This was a huge effort
www.biorxiv.org/content/10.1...
Ventral striatal astrocytes contribute to reinforcement learning
Astrocytes influence synaptic plasticity and neuronal function through astrocytic calcium dynamics (ACD). However, astrocytes contribution to cognitive operations like reinforcement learning (RL) rema...
www.biorxiv.org
October 21, 2025 at 1:28 AM
How do non-neuronal CNS cells called astrocytes contribute to cognition & computation?
See our preprint
Headed by my students Julia Pai and Fatih Sogukpinar, also working with Hiratani, Pignatelli, Papouin, Frank, and Ching labs. This was a huge effort
www.biorxiv.org/content/10.1...
See our preprint
Headed by my students Julia Pai and Fatih Sogukpinar, also working with Hiratani, Pignatelli, Papouin, Frank, and Ching labs. This was a huge effort
www.biorxiv.org/content/10.1...
Some professional news : My team is moving to Johns Hopkins University this Summer. I am deeply grateful to Washington University for supporting us since 2014. It has been an amazing journey full of brilliant colleagues and friends.
May 5, 2025 at 2:26 AM
Some professional news : My team is moving to Johns Hopkins University this Summer. I am deeply grateful to Washington University for supporting us since 2014. It has been an amazing journey full of brilliant colleagues and friends.
New work!
How does perceptual novelty impact the value of (physical) rewards: what are the underlying algorithms and neural mechanisms?
The answers may help to construct smarter AIs and to understand how and why novelty seeking breaks in psychiatric disorders.
www.biorxiv.org/content/10.1...
How does perceptual novelty impact the value of (physical) rewards: what are the underlying algorithms and neural mechanisms?
The answers may help to construct smarter AIs and to understand how and why novelty seeking breaks in psychiatric disorders.
www.biorxiv.org/content/10.1...
Temporal-orbitofrontal pathway regulates choices across physical reward and visual novelty
Perceptually novel objects have profound impacts on our daily decisions. People often pay to try novel meals over familiar ones, or to see novel visual scenes at art exhibits and travel destinations. ...
www.biorxiv.org
April 21, 2025 at 2:06 AM
New work!
How does perceptual novelty impact the value of (physical) rewards: what are the underlying algorithms and neural mechanisms?
The answers may help to construct smarter AIs and to understand how and why novelty seeking breaks in psychiatric disorders.
www.biorxiv.org/content/10.1...
How does perceptual novelty impact the value of (physical) rewards: what are the underlying algorithms and neural mechanisms?
The answers may help to construct smarter AIs and to understand how and why novelty seeking breaks in psychiatric disorders.
www.biorxiv.org/content/10.1...
First blue sky post is to celebrate! Incredibly proud of Dr Julia Pai. Fantastic defense and pioneering project on non-neuronal cells in Reinforcement Learning! Now almost off to her next chapter. Paper in prep!
January 28, 2025 at 1:45 PM
First blue sky post is to celebrate! Incredibly proud of Dr Julia Pai. Fantastic defense and pioneering project on non-neuronal cells in Reinforcement Learning! Now almost off to her next chapter. Paper in prep!