Ale Mongera
@mongeralab.bsky.social
Pinned
Ale Mongera
@mongeralab.bsky.social
· Sep 11
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Reposted by Ale Mongera
With more than 2.1k citations, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the CNV Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described. #ZebrafishFunFacts 🧪
November 29, 2025 at 6:29 AM
With more than 2.1k citations, 'The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio' by the CNV Lab highlighted the arduous work that took place during 'The Big Screen'. In total, 1163 mutants were described. #ZebrafishFunFacts 🧪
Reposted by Ale Mongera
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
November 27, 2025 at 8:47 AM
So called microtubule organizing centers (MTOCs) are not "organizing centers". They don't control their position (network center), nor MT orientation, length and shape (network shape). The actual organizers are MTs, molecular motors and regulators of MT +ends. MTOCs nucleate MTs.
Let's rename MTOCs.
Let's rename MTOCs.
Reposted by Ale Mongera
Thought I was being really novel when I designed and 3D printed this mold for zebrafish transplants based on the microinjection one, but found out today it already exists…
Bottom: my PLA mold that’s bent from warm agarose
Top: a very kind (more robust looking) gift from @mongeralab.bsky.social
Bottom: my PLA mold that’s bent from warm agarose
Top: a very kind (more robust looking) gift from @mongeralab.bsky.social
November 26, 2025 at 5:58 PM
Thought I was being really novel when I designed and 3D printed this mold for zebrafish transplants based on the microinjection one, but found out today it already exists…
Bottom: my PLA mold that’s bent from warm agarose
Top: a very kind (more robust looking) gift from @mongeralab.bsky.social
Bottom: my PLA mold that’s bent from warm agarose
Top: a very kind (more robust looking) gift from @mongeralab.bsky.social
Reposted by Ale Mongera
Cell type-independent timekeeping gene modules enable embryonic stage prediction in zebrafish https://www.biorxiv.org/content/10.1101/2025.11.12.688039v1
November 13, 2025 at 8:34 PM
Cell type-independent timekeeping gene modules enable embryonic stage prediction in zebrafish https://www.biorxiv.org/content/10.1101/2025.11.12.688039v1
Reposted by Ale Mongera
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
November 12, 2025 at 3:35 PM
Stationary and germ layer-specific cellular flows shape the zebrafish gastrula https://www.biorxiv.org/content/10.1101/2025.11.10.687746v1
Reposted by Ale Mongera
How can we organize current theoretical approaches for developmental biology - from information to dynamical systems & GRNs - into a common framework?
We propose to think along Marr's 3 levels: computational problem, algorithm, implementation
Check out our review:
arxiv.org/abs/2510.24536
We propose to think along Marr's 3 levels: computational problem, algorithm, implementation
Check out our review:
arxiv.org/abs/2510.24536
November 10, 2025 at 6:46 AM
How can we organize current theoretical approaches for developmental biology - from information to dynamical systems & GRNs - into a common framework?
We propose to think along Marr's 3 levels: computational problem, algorithm, implementation
Check out our review:
arxiv.org/abs/2510.24536
We propose to think along Marr's 3 levels: computational problem, algorithm, implementation
Check out our review:
arxiv.org/abs/2510.24536
Reposted by Ale Mongera
We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕
🔗 About our lab: renew.science/principal_in...
🎓 PhD position: jobportal.ku.dk/phd/?show=15...
🧪 Postdoc position: jobportal.ku.dk/videnskabeli...
🔗 About our lab: renew.science/principal_in...
🎓 PhD position: jobportal.ku.dk/phd/?show=15...
🧪 Postdoc position: jobportal.ku.dk/videnskabeli...
November 3, 2025 at 7:05 PM
We are looking for: PhD Student (starting as Research Assistant) and Postdoctoral Researcher in Stem Cell Biology and Mechanobiology. Please RT💕
🔗 About our lab: renew.science/principal_in...
🎓 PhD position: jobportal.ku.dk/phd/?show=15...
🧪 Postdoc position: jobportal.ku.dk/videnskabeli...
🔗 About our lab: renew.science/principal_in...
🎓 PhD position: jobportal.ku.dk/phd/?show=15...
🧪 Postdoc position: jobportal.ku.dk/videnskabeli...
Reposted by Ale Mongera
🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬
This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!
www.findaphd.com/phds/project... 🧪
This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!
www.findaphd.com/phds/project... 🧪
November 3, 2025 at 2:46 PM
🚨 Come join us @sheffielduni.bsky.social for a PhD on the evolution and development of feathers and flight! 🐣🔬
This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!
www.findaphd.com/phds/project... 🧪
This project is supervised by @matt-towers.bsky.social & @alexgfletcher.bsky.social, and I'm excited to be involved as a project advisor. Please share!
www.findaphd.com/phds/project... 🧪
Reposted by Ale Mongera
Had the pleasure of working with @mohannad-dardiry.bsky.social to rethink what it means to develop for life. Many thanks to @dev-journal.bsky.social! @embl.org #LifelongDevSI
October 31, 2025 at 11:24 AM
Had the pleasure of working with @mohannad-dardiry.bsky.social to rethink what it means to develop for life. Many thanks to @dev-journal.bsky.social! @embl.org #LifelongDevSI
Reposted by Ale Mongera
Happy birthday to #LaskerLaureate Christiane Nüsslein-Volhard! She identified 120 genes involved in specifying embryonic pattern development.
Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM 🧪
Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM 🧪
I Dreamt of Fruit Flies - Lasker Foundation
In the mid-1970s, Christiane Nüsslein-Volhard was struggling. Two years after finishing her PhD in molecular biology, she was working as a postdoctoral researcher in a lab she longed to leave. The…
ow.ly
October 20, 2025 at 4:32 PM
Happy birthday to #LaskerLaureate Christiane Nüsslein-Volhard! She identified 120 genes involved in specifying embryonic pattern development.
Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM 🧪
Read about the epic screen that yielded her Lasker Award-winning results: ow.ly/Pz2050PYFsz #WomenInSTEM 🧪
Reposted by Ale Mongera
We are hiring ! If you want to become professor of Bioinformatics in the best city of North America, check the announcement below ! Also you do need to speak French (as long as you commit to learning it :) ) www.umontreal.ca/public/www/d...
www.umontreal.ca
October 10, 2025 at 11:48 AM
We are hiring ! If you want to become professor of Bioinformatics in the best city of North America, check the announcement below ! Also you do need to speak French (as long as you commit to learning it :) ) www.umontreal.ca/public/www/d...
Reposted by Ale Mongera
Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.
More here: elifesciences.org/reviewed-pre...
More here: elifesciences.org/reviewed-pre...
elifesciences.org
September 29, 2025 at 8:45 AM
Can pressure gradients persist over long timescales in animal cells? We induced intracellular pressure gradients and examined the resulting flows in single cells. We reveal surprisingly long lasting pressure gradients.
More here: elifesciences.org/reviewed-pre...
More here: elifesciences.org/reviewed-pre...
Super cool! Looking forward to trying this reporter!
🚨 Excited to introduce FuChi (Fucci chicken), the first avian cell cycle reporter line. Thank you to all those who contributed to putting this paper together. I really think it showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬 @roslininstitute.bsky.social
September 26, 2025 at 11:26 AM
Super cool! Looking forward to trying this reporter!
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
September 11, 2025 at 9:36 AM
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome!
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
Reposted by Ale Mongera
Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...
Nodal Signaling: A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews
Nodal signaling molecules are TGFβ family ligands that arose early during bilaterian evolution and are crucial for several key steps in embryonic development. They regulate the specification of mesode...
www.annualreviews.org
August 10, 2025 at 2:16 PM
Everything (and more) you wanted to know about Nodal Signaling. A Paradigm for TGFβ Signaling in Embryonic Development | Annual Reviews - www.annualreviews.org/content/jour...
Reposted by Ale Mongera
Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium:
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬
📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden
Register now (Deadline 31 July 2025): engineering-life-dresden.de
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬
📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden
Register now (Deadline 31 July 2025): engineering-life-dresden.de
July 28, 2025 at 3:44 PM
Few spots left on our @bcube-tud.bsky.social organised hashtag #Symposium:
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬
📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden
Register now (Deadline 31 July 2025): engineering-life-dresden.de
Engineering Life 2025: Origin and Function of Mechanical Forces in Biology ⚙️🧬
📆 September 1-3, 2025
📍 Steigenberger Hotel de Saxe, Dresden
Register now (Deadline 31 July 2025): engineering-life-dresden.de
Reposted by Ale Mongera
After 15 years of controversy, @science.org retracts ‘arsenic life’ paper
After 15 years of controversy, Science retracts ‘arsenic life’ paper
Science has retracted a 2010 paper describing a strain of bacteria that purportedly substituted arsenic for phosphorus, an element present in all known life. Science/AAAS Fifteen years after publis…
retractionwatch.com
July 24, 2025 at 6:16 PM
After 15 years of controversy, @science.org retracts ‘arsenic life’ paper
Reposted by Ale Mongera
Somatic cells compartmentalise their metabolism to sustain germ cell survival https://www.biorxiv.org/content/10.1101/2025.07.22.666113v1
July 22, 2025 at 8:31 PM
Somatic cells compartmentalise their metabolism to sustain germ cell survival https://www.biorxiv.org/content/10.1101/2025.07.22.666113v1
Great thread by @amichaut.bsky.social
Check out this thread I wrote for @epimechfc.bsky.social ⬇️
If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
July 20, 2025 at 12:09 PM
Great thread by @amichaut.bsky.social
Reposted by Ale Mongera
Check out this thread I wrote for @epimechfc.bsky.social ⬇️
If you’ve been following this account closely, you might already know methods to probe mechanics in vitro, but what about in live embryos?
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
I’m @amichaut.bsky.social, and I’m going to share a few great papers on this aspect of #EpithelialMechanics.
July 20, 2025 at 9:11 AM
Check out this thread I wrote for @epimechfc.bsky.social ⬇️
Reposted by Ale Mongera
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
July 10, 2025 at 10:16 AM
SARCOMERES divide! Mechanism how muscles grow while contracting - daughter sarcomeres appear everywhere. Seen live, registered on our cover. Pioneered by @clementrodier.bsky.social @friedrich-group.bsky.social Ian Estabrook @ibdm.bsky.social $ by @hfspo.bsky.social www.science.org/doi/10.1126/...
Reposted by Ale Mongera
Why do vertex models work so well to predict tissue fluidity/rigidity, even though they are simple and possibly even wrong? A new paper in PRX Life
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...
Universality in the Mechanical Behavior of Vertex Models for Biological Tissues
A systematic comparison of diverse cell packing models reveals shared mechanical rules that govern how tissues stiffen, yield, and reorganize---shedding light on the physical logic behind morphogenesi...
journals.aps.org
July 9, 2025 at 12:10 AM
Why do vertex models work so well to predict tissue fluidity/rigidity, even though they are simple and possibly even wrong? A new paper in PRX Life
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...
@prxlife.bsky.social, spearheaded by @sadjadarzash.bsky.social and Ojan Damavandi, suggests universality may explain: journals.aps.org/prxlife/abst...
Reposted by Ale Mongera
June 28, 2025 at 4:19 PM
Reposted by Ale Mongera
The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism
Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita.
#Workshop #Biology #CellBiology #Community #Collaboration #Research
Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita.
#Workshop #Biology #CellBiology #Community #Collaboration #Research
June 26, 2025 at 8:57 AM
The Company of Biologists Workshop - Mechanometabolism Unleashed: The Interface of Cell Mechanics and Metabolism
Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita.
#Workshop #Biology #CellBiology #Community #Collaboration #Research
Thank you to Workshop organisers Marco Foiani, Ana-Maria Lennon-Duménil, Victoria Sanz-Moreno and Giorgio Scita.
#Workshop #Biology #CellBiology #Community #Collaboration #Research
Reposted by Ale Mongera
A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1
June 6, 2025 at 12:31 PM
A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics https://www.biorxiv.org/content/10.1101/2025.06.06.658228v1