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mlisboaperez.bsky.social
@mlisboaperez.bsky.social
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mlisboaperez.bsky.social
Very happy to see our manuscript officially published at #NatureCommunications! It was a new and exciting journey for me, previously researching on CS topics, to work on this richly multi-disciplinary project www.nature.com/articles/s41...
#AI @nanoporetech.com #DNASequencing #SyntheticBiology
Direct high-throughput deconvolution of non-canonical bases via nanopore sequencing and bootstrapped learning - Nature Communications
Perez, Kimoto, Rajakumar and colleagues present a fast and accurate DNA sequencing method that reads canonical and non-canonical bases using AI and nanopore technology. The approach enables an expande...
www.nature.com
August 8, 2025 at 6:25 AM
mlisboaperez.bsky.social
Excited to share our latest work, where we show how to achieve high-throughput sequencing of DNA containing non-canonical bases using Nanopore (@nanoporetech.com) and de novo basecalling enabled by spliced-based data-augmentation.
#nanopore #basecaller #syntheticbiology
Direct high-throughput deconvolution of unnatural bases via nanopore sequencing and bootstrapped learning
The discovery of synthetic xeno-nucleic acids (XNAs) that can basepair as unnatural bases (UBs) to expand the genetic alphabet has spawned interest in many applications, from synthetic biology to DNA ...
biorxiv.org
December 5, 2024 at 9:52 AM