Mireya Plass
@mireyaplass.bsky.social
Associate professor at Universitat de Barcelona.
Studying post transcriptional regulation in single cells and Alzheimer's Disease. iPSCs, gene regulatory networks, bioinformatics, systems biology
https://www.plasslab.com/
Studying post transcriptional regulation in single cells and Alzheimer's Disease. iPSCs, gene regulatory networks, bioinformatics, systems biology
https://www.plasslab.com/
Reposted by Mireya Plass
"Bulk RNA-seq to the rescue of differential expression analysis in single-cell transcriptomics" 🧫 📑 A new PCI Genomics recommendation by @mireyaplass.bsky.social: doi.org/10.24072/pci...
Bulk RNA-seq to the rescue of differential expression analysis i...
Due to the costs of single-cell sequencing, sample sizes are often relatively limited, sometimes leading to poorly reproducible results. In many contexts, however, larger bulk RNAseq data is…
doi.org
December 1, 2025 at 8:30 AM
"Bulk RNA-seq to the rescue of differential expression analysis in single-cell transcriptomics" 🧫 📑 A new PCI Genomics recommendation by @mireyaplass.bsky.social: doi.org/10.24072/pci...
Reposted by Mireya Plass
🚨Interested in studing RNA regulation & neurodegeneration in single-cells?
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
www.aei.gob.es
November 3, 2025 at 9:55 AM
🚨Interested in studing RNA regulation & neurodegeneration in single-cells?
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
Reposted by Mireya Plass
Hey everyone! I’m excited to share that one of my thesis projects was just published in @currentbiology.bsky.social and featured on phys.org! In this paper, we use an old statistical approach developed by the US Navy in WW2 to predict the aquatic habits of various dinosaurs and marine reptiles 🦖🐊
November 20, 2025 at 8:51 PM
Hey everyone! I’m excited to share that one of my thesis projects was just published in @currentbiology.bsky.social and featured on phys.org! In this paper, we use an old statistical approach developed by the US Navy in WW2 to predict the aquatic habits of various dinosaurs and marine reptiles 🦖🐊
Reposted by Mireya Plass
¡Ya llevamos 212.352€ recaudados! Estamos más cerca que nunca de lograr crear el algoritmo capaz de anticiparse al Alzheimer. Ayúdanos a seguir investigando 🧠🔬.
Dona ahora en anticiparsealalzheimer.org
Dona ahora en anticiparsealalzheimer.org
November 21, 2025 at 9:30 AM
¡Ya llevamos 212.352€ recaudados! Estamos más cerca que nunca de lograr crear el algoritmo capaz de anticiparse al Alzheimer. Ayúdanos a seguir investigando 🧠🔬.
Dona ahora en anticiparsealalzheimer.org
Dona ahora en anticiparsealalzheimer.org
Reposted by Mireya Plass
Integrated analysis of multimodal long-read epigenetic assays https://www.biorxiv.org/content/10.1101/2025.11.09.687458v1
November 10, 2025 at 3:36 AM
Integrated analysis of multimodal long-read epigenetic assays https://www.biorxiv.org/content/10.1101/2025.11.09.687458v1
🚨Interested in studing RNA regulation & neurodegeneration in single-cells?
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
www.aei.gob.es
November 3, 2025 at 9:55 AM
🚨Interested in studing RNA regulation & neurodegeneration in single-cells?
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
Join my lab @ub.edu in Barcelona!
We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
Reposted by Mireya Plass
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
October 30, 2025 at 5:50 PM
🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
📅 Starting date early 2026, with some flexibility.
🙏Please, RT!
Finally after 5 years the first PhD from the lab!
Congratulations Dr. Ake @franzake.bsky.social !!! 👏👏👏 🎉🎉🎉
It has been a pleasure to have you in the lab. #PhD_defense #new_PhD
Congratulations Dr. Ake @franzake.bsky.social !!! 👏👏👏 🎉🎉🎉
It has been a pleasure to have you in the lab. #PhD_defense #new_PhD
October 30, 2025 at 12:28 PM
Finally after 5 years the first PhD from the lab!
Congratulations Dr. Ake @franzake.bsky.social !!! 👏👏👏 🎉🎉🎉
It has been a pleasure to have you in the lab. #PhD_defense #new_PhD
Congratulations Dr. Ake @franzake.bsky.social !!! 👏👏👏 🎉🎉🎉
It has been a pleasure to have you in the lab. #PhD_defense #new_PhD
Reposted by Mireya Plass
Excited and grateful to be part of this work with @smfernandezmoya.bsky.social and @mireyaplass.bsky.social at the Gene Regulation of Cell Identity lab!
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
www.biorxiv.org
October 3, 2025 at 11:58 AM
Excited and grateful to be part of this work with @smfernandezmoya.bsky.social and @mireyaplass.bsky.social at the Gene Regulation of Cell Identity lab!
Reposted by Mireya Plass
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
www.biorxiv.org
October 2, 2025 at 4:40 PM
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
This project would have been impossible without the work of our collaborators Agnieskza Rybak-Wolf, @monikapiwecka.bsky.social & Alessandra Gioregtti.
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
www.biorxiv.org
October 3, 2025 at 3:47 PM
This project would have been impossible without the work of our collaborators Agnieskza Rybak-Wolf, @monikapiwecka.bsky.social & Alessandra Gioregtti.
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Staufen2 modulates the temporal dynamics of human neurogenesis in vitro
RNA-binding proteins (RBPs) play a central role in post-transcriptional regulation during brain development, yet their specific functions in coordinating human neural lineage decisions remain poorly u...
www.biorxiv.org
October 2, 2025 at 4:40 PM
🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Mireya Plass
Very happy to share the peer-reviewed version of our work on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4, published in @natsmb.nature.com!
rdcu.be/ezGqT
Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
rdcu.be/ezGqT
Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
Core splicing architecture and early spliceosomal recognition determine microexon sensitivity to SRRM3/4
Nature Structural & Molecular Biology - Using massively parallel splicing assays and mathematical modeling, Bonnal et al. uncover that conserved splice site strength and exon length encode...
rdcu.be
August 7, 2025 at 10:37 AM
Very happy to share the peer-reviewed version of our work on the cis-regulatory determinants of #microexon #splicing regulation by SRRM3/4, published in @natsmb.nature.com!
rdcu.be/ezGqT
Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
rdcu.be/ezGqT
Work led by @sobonnal.bsky.social, with Simon Bajew & @rmartinezcorral.bsky.social. @crg.eu @upf.edu
Reposted by Mireya Plass
🧬🧬🧬 New review from the lab:
Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks
authors.elsevier.com/sd/article/S...
By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.
Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks
authors.elsevier.com/sd/article/S...
By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.
August 6, 2025 at 9:16 AM
🧬🧬🧬 New review from the lab:
Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks
authors.elsevier.com/sd/article/S...
By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.
Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks
authors.elsevier.com/sd/article/S...
By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.
Reposted by Mireya Plass
🎓 Just graduated and passionate about Computational #Biology, Structural Biology, #Genomics or #Neurogenomics? Apply by 8 Sept for 1 of 9 fully funded PhD scholarships via the SEMM Program at HT in Milan!
👉 humantechnopole.it/en/news/call... #PhDlife
👉 humantechnopole.it/en/news/call... #PhDlife
Call for Applications: Fully Funded PhD Scholarships in Systems Medicine - Human Technopole
Are you passionate about science and ready to take the next step in your research journey? Human Technopole is offering up to 9 fully funded PhD scholarships through the highly regarded SEMM PhD Progr...
humantechnopole.it
July 29, 2025 at 7:40 AM
🎓 Just graduated and passionate about Computational #Biology, Structural Biology, #Genomics or #Neurogenomics? Apply by 8 Sept for 1 of 9 fully funded PhD scholarships via the SEMM Program at HT in Milan!
👉 humantechnopole.it/en/news/call... #PhDlife
👉 humantechnopole.it/en/news/call... #PhDlife
If you like our recent work and are interested in developing a postdoc project related to isoform diversity in individual cell types and their regulation, get in contact!
We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing
We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing
I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
www.nature.com
July 28, 2025 at 7:24 AM
If you like our recent work and are interested in developing a postdoc project related to isoform diversity in individual cell types and their regulation, get in contact!
We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing
We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing
Reposted by Mireya Plass
🚨🚨🚨
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
www.upf.edu
July 23, 2025 at 2:28 PM
🚨🚨🚨
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Please RT!
We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets.
Deadline: 30/09/25👇
Reposted by Mireya Plass
Quantification of transcript isoforms at the single-cell level using SCALPEL nature.com/articles/s41... by @miriplass.bsky.social and her team
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
nature.com
July 18, 2025 at 12:51 PM
Quantification of transcript isoforms at the single-cell level using SCALPEL nature.com/articles/s41... by @miriplass.bsky.social and her team
Reposted by Mireya Plass
Join our "Advances in Single-Cell Technologies" meeting in December in Freiburg, co-organised with Marco Prinz and @katrinkierdorf.bsky.social. Excellent line-up of speakers covering spatial technologies, lineage tracing, computational methods, and more.
www.uniklinik-freiburg.de/single-cell-...
www.uniklinik-freiburg.de/single-cell-...
July 21, 2025 at 6:15 AM
Join our "Advances in Single-Cell Technologies" meeting in December in Freiburg, co-organised with Marco Prinz and @katrinkierdorf.bsky.social. Excellent line-up of speakers covering spatial technologies, lineage tracing, computational methods, and more.
www.uniklinik-freiburg.de/single-cell-...
www.uniklinik-freiburg.de/single-cell-...
Reposted by Mireya Plass
L’estudi de #recercaUB sobre l'eina #SCALPEL que ha liderat @mireyaplass.bsky.social s’ha publicat el juliol en #openaccess a la revista @natcomms.nature.com.
#RecercaUB | 🔬 Un equip liderat de la #UniBarcelona i @idibell.bsky.social desenvolupa una eina per quantificar i caracteritzar l’ARNm amb una sensibilitat i especificitat molt superiors als mètodes actuals.
🎓 Lidera l’estudi Mireya Plass, de @medicinacs-ub.bsky.social.
🎓 Lidera l’estudi Mireya Plass, de @medicinacs-ub.bsky.social.
SCALPEL: analitzar l’expressió gènica en alta resolució
web.ub.edu
July 18, 2025 at 11:00 AM
L’estudi de #recercaUB sobre l'eina #SCALPEL que ha liderat @mireyaplass.bsky.social s’ha publicat el juliol en #openaccess a la revista @natcomms.nature.com.
Reposted by Mireya Plass
🚨The #NextflowSummit Call for Speakers and Posters is Now Open! 🚨
🎤 Present your talk or poster at the Virtual #NextflowSummit by @seqera.io (Oct 23–24).
📍Or showcase your poster in-person in Barcelona at the Nextflow Training and @nf-co.re Hackathon (Oct 28–29)
hubs.la/Q03xGPp_0
🎤 Present your talk or poster at the Virtual #NextflowSummit by @seqera.io (Oct 23–24).
📍Or showcase your poster in-person in Barcelona at the Nextflow Training and @nf-co.re Hackathon (Oct 28–29)
hubs.la/Q03xGPp_0
July 17, 2025 at 3:32 PM
🚨The #NextflowSummit Call for Speakers and Posters is Now Open! 🚨
🎤 Present your talk or poster at the Virtual #NextflowSummit by @seqera.io (Oct 23–24).
📍Or showcase your poster in-person in Barcelona at the Nextflow Training and @nf-co.re Hackathon (Oct 28–29)
hubs.la/Q03xGPp_0
🎤 Present your talk or poster at the Virtual #NextflowSummit by @seqera.io (Oct 23–24).
📍Or showcase your poster in-person in Barcelona at the Nextflow Training and @nf-co.re Hackathon (Oct 28–29)
hubs.la/Q03xGPp_0
Reposted by Mireya Plass
Two new preprints from the @arjunraj.bsky.social on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
July 15, 2025 at 1:28 PM
Two new preprints from the @arjunraj.bsky.social on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
biorxiv.org/content/earl...
Reposted by Mireya Plass
A computational tool #SCALPEL for #isoform quantification at the single-cell level using 3’ scRNA-seq data @franzake.bsky.social @mireyaplass.bsky.social #BiotechNatureComms
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
doi.org
July 13, 2025 at 5:41 PM
A computational tool #SCALPEL for #isoform quantification at the single-cell level using 3’ scRNA-seq data @franzake.bsky.social @mireyaplass.bsky.social #BiotechNatureComms
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Mireya Plass
I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Quantification of transcript isoforms at the single-cell level using SCALPEL - Nature Communications
Single-cell RNA-seq facilitates the study of transcriptome diversity in individual cells. Here, authors introduce a tool for isoform quantification at the single-cell level using 3’ scRNA-seq data, co...
www.nature.com
July 14, 2025 at 10:31 AM
I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms
www.nature.com/articles/s41...
www.nature.com/articles/s41...