MedComm
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MedComm
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MedComm is a peer‐reviewed, online OA journal that publishes the pioneer works of medicine on the basis of novelty, timeliness and significance on human health.
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MedComm @medcomm.bsky.social · 3d
🎉Congratulations！

In the recently released JCR Impact Factor 2024, MedComm maintained an IF of 10.7, placing it in the Q1 category for Medicine, Research & Experimental, ranking 14/195. Welcome to submit your next manuscripts to MedComm!

#JCR2025 #TrustedJournals #ImpactFactor
medcomm.bsky.social
🎉Congratulations！

In the recently released JCR Impact Factor 2024, MedComm maintained an IF of 10.7, placing it in the Q1 category for Medicine, Research & Experimental, ranking 14/195. Welcome to submit your next manuscripts to MedComm!

#JCR2025 #TrustedJournals #ImpactFactor
November 7, 2025 at 8:36 AM
medcomm.bsky.social
#Article in #MedComm
Neurofilament Light Chains in Serum Predict Post—Transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy doi.org/10.1002/mco2...

#AxonalDamage #biomarker #CognitiveDysfunction #TIPS #GFAP
Neurofilament Light Chains in Serum Predict Post—Transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy
Hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) insertion constitutes a frequent and severe complication, however, biomarkers are currently scarce. The results ...
doi.org
November 7, 2025 at 8:23 AM
medcomm.bsky.social
#Article in #MedComm
Chidamide (a Histone Deacetylase Inhibitor) Plus Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC): A Phase Ib Trial doi.org/10.1002/mco2...
#Clinicaltrial #EpigeneticRegulation #HistoneDeacetylase #mCRPC
Chidamide (a Histone Deacetylase Inhibitor) Plus Abiraterone in Metastatic Castration‐Resistant Prostate Cancer (mCRPC): A Phase Ib Trial
Metastatic castration-resistant prostate cancer (mCRPC) remains challenging. This Phase Ib trial tested chidamide, a selective HDAC inhibitor, plus abiraterone in 18 patients. The regimen was well to...
doi.org
November 7, 2025 at 8:21 AM
medcomm.bsky.social
#Review in #MedComm
Artificial Intelligence for the Diagnosis and Management of Cancers: Potentials and Challenges doi.org/10.1002/mco2...

#ArtificialIntelligence #AI #cancer #CancerDiagnosis #PrognosisPrediction #personalized #therapy
Artificial Intelligence for the Diagnosis and Management of Cancers: Potentials and Challenges
Artificial intelligence (AI) is a rising star in the field of medicine, avoiding misdiagnosis by human negligence, reducing the workload of doctors, and aiding clinicians in decision-making. AI can i...
doi.org
November 7, 2025 at 8:20 AM
medcomm.bsky.social
#Review in #MedComm @wiley.com
Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential doi.org/10.1002/mco2...

#BiologicalFunction #Classification #development #DendriticCell #Origin #TherapeuticPotential
Dendritic Cells: Origin, Classification, Development, Biological Functions, and Therapeutic Potential
This review systematically summarizes dendritic cells (DCs) originating from hematopoietic stem cells, their major subsets (cDC1s, cDC2s, pDCs, moDCs, LCs) and core functions (antigen capture/present...
doi.org
November 7, 2025 at 8:20 AM
medcomm.bsky.social
#Article in #MedComm
SARS-CoV-2 Spike Protein as a Target of the COVID-19 Vaccine Disrupts Insulin Signaling in Type 2 Diabetes doi.org/10.1002/mco2...

#COVID_19 #diabetes #InsulinSensitivity #SARS_CoV_2
#Vaccine #Protein #Target
SARS‐CoV‐2 Spike Protein as a Target of the COVID‐19 Vaccine Disrupts Insulin Signaling in Type 2 Diabetes
SARS Cov-2 spike protein disrupts insulin signaling in type 2 diabetes as a target of the COVID-19 vaccine in subject with type 2 diabetes (T2D), while metformin improved the insulin signaling variat...
doi.org
November 7, 2025 at 8:19 AM
medcomm.bsky.social
#Article in #MedComm @wiley.com
Synthesized Depside Molecules Suppress the Progression of Colorectal Cancer by Binding VDAC1/PHB/MMP9 Being at the Crossroads of Stemness, Motility, Apoptosis, and Metabolism doi.org/10.1002/mco2...

#MMP #prohibitin1 #VDAC1 #probe #BindingIdentification
Synthesized Depside Molecules Suppress the Progression of Colorectal Cancer by Binding VDAC1/PHB/MMP9 Being at the Crossroads of Stemness, Motility, Apoptosis, and Metabolism
This study suggests that newly synthesized depside compounds suppress the progression of colorectal cancer by directly targeting VDAC1/PHB/MMP9. Especially, SB4 demonstrated significant bioavailabili...
doi.org
November 7, 2025 at 8:19 AM
medcomm.bsky.social
#Review in #MedComm
Mucosal-Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets doi.org/10.1002/mco2...

#AutoimmuneDisease #cancer #Immunotherapy #InfectiousDisease #MAITcell #MR1 #UnconventionalTcell #MAIT
Mucosal‐Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets
Mucosa-associated invariant T (MAIT) cells are an evolutionarily conserved class of innate-like T lymphocytes that rely on MR1 molecules to recognize microbial metabolites and play a central role in ...
doi.org
November 7, 2025 at 8:17 AM
medcomm.bsky.social
#Review in #MedComm
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9): The Multifaceted Biology, Diseases, and Pharmaceutical Interventions doi.org/10.1002/mco2...

#PCSK9 #LDL_C #IschemicStroke #Intervention #Strategies #PrecisionTherapy #therapeutics
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9): The Multifaceted Biology, Diseases, and Pharmaceutical Interventions
Summary of PCSK9 inhibitor mechanisms. PCSK9 inhibitors (PCSK9-i) primarily lower LDL-cholesterol (LDL-C) by blocking PCSK9-mediated degradation of hepatic LDL receptors (LDLR), enhancing LDL clearan....
doi.org
November 7, 2025 at 8:16 AM
medcomm.bsky.social
#Article in @MedComm_MC
Discovering Heterogeneous Leukocytes Subsets Associated With Alcoholic Steatohepatitis by #scRNAseq Analysis doi.org/10.1002/mco2...

#AlcoholicLiverDisease #AlcoholicSteatohepatitis #Bcell #ImmuneCell #Neutrophil #tSNEs
Discovering Heterogeneous Leukocytes Subsets Associated With Alcoholic Steatohepatitis by scRNAseq Analysis
In this study, we explored comprehensive profiling of heterogeneous immune leukocytes at a single-cell level using scRNAseq analysis to discover the regulation of inflammatory-mediated liver fibrosis...
doi.org
November 7, 2025 at 8:16 AM
medcomm.bsky.social
#Article in #MedComm_Biomaterials_and_Applicaitons
VCAM-1-Functionalized Iron Oxide Nanoclusters for Targeted MRI-Based Diagnosis of Atherosclerosis doi.org/10.1002/mba2...

#diagnosis #atherosclerosis #Nanocluster #MRI #nanoparticles #vehicles
VCAM‐1‐Functionalized Iron Oxide Nanoclusters for Targeted MRI‐Based Diagnosis of Atherosclerosis
This study explores the functionalization of iron oxide nanoclusters (NCs) as targeted magnetic resonance imaging (MRI) contrast agents. Modifications preserve colloidal stability, crucial for biodis...
doi.org
November 7, 2025 at 8:09 AM
medcomm.bsky.social
#Article in #MedComm_Oncology

Parkinson's Disease and Cancer: Mechanistic Insights and Therapeutic Opportunities From Cancer Neuroscience doi.org/10.1002/mog2...

#cancer #CancerNeuroscience #gliomas #NeurodegenerativeDisease #PD #Therapeutic #Neuroscience
November 7, 2025 at 8:07 AM