Mathieu Decloquement
@mathd34.bsky.social
Postdoctoral Fellow in Macauley lab, UofA, Edmonton.
PhD in Glycobiology in Harduin-Lepers team, UGSF, Univ. Lille.
PhD in Glycobiology in Harduin-Lepers team, UGSF, Univ. Lille.
Reposted by Mathieu Decloquement
Excited to share our laboratory's research tools to study Siglecs along with some interesting discoveries with these tools. Lot of help from many group, but @zeinab-jc.bsky.social was the major driver of this work. Please reach out if you would like to try them out. www.science.org/doi/10.1126/...
An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function
Siglec-liposomes are a multivalent and modular platform for profiling Siglec ligands and modulating immune cell function.
www.science.org
November 12, 2025 at 9:57 PM
Excited to share our laboratory's research tools to study Siglecs along with some interesting discoveries with these tools. Lot of help from many group, but @zeinab-jc.bsky.social was the major driver of this work. Please reach out if you would like to try them out. www.science.org/doi/10.1126/...
Reposted by Mathieu Decloquement
An amazing week at University of Alberta 🇨🇦with plenty of #glycotime! A big thanks to @glycocode.bsky.social , @giaglyco.bsky.social and to @glyconet.bsky.social for the kind invitation!! Also great to see inspiring glyco-researchers that marked a generation
November 10, 2025 at 7:45 PM
An amazing week at University of Alberta 🇨🇦with plenty of #glycotime! A big thanks to @glycocode.bsky.social , @giaglyco.bsky.social and to @glyconet.bsky.social for the kind invitation!! Also great to see inspiring glyco-researchers that marked a generation
Great two glyco-days at #GIA2025 🍬
Honored to introduce Prof. Jim Paulson ⭐
Exciting glyco talks, amazing chats ☕, and valuable feedback for the next steps in my project 💡 #glycotime
Honored to introduce Prof. Jim Paulson ⭐
Exciting glyco talks, amazing chats ☕, and valuable feedback for the next steps in my project 💡 #glycotime
November 9, 2025 at 6:52 PM
Great two glyco-days at #GIA2025 🍬
Honored to introduce Prof. Jim Paulson ⭐
Exciting glyco talks, amazing chats ☕, and valuable feedback for the next steps in my project 💡 #glycotime
Honored to introduce Prof. Jim Paulson ⭐
Exciting glyco talks, amazing chats ☕, and valuable feedback for the next steps in my project 💡 #glycotime
Reposted by Mathieu Decloquement
Wonderful day 2 of #GIA2025 @giaglyco.bsky.social ! We started off with an outstanding talk from @salomepinho.bsky.social followed by a spectacular day of science with talks from @rlhull-meichle.bsky.social, Jason Northey, Alisdair Boraston and Trainees Sogand Makhsous and @mathd34.bsky.social!
November 8, 2025 at 12:38 AM
Wonderful day 2 of #GIA2025 @giaglyco.bsky.social ! We started off with an outstanding talk from @salomepinho.bsky.social followed by a spectacular day of science with talks from @rlhull-meichle.bsky.social, Jason Northey, Alisdair Boraston and Trainees Sogand Makhsous and @mathd34.bsky.social!
Reposted by Mathieu Decloquement
Save the date for #GIA2026 (Nov. 5-6, 2026) which will feature free #glycotime talks by @carolynbertozzi.bskyverified.social , Dr. Mia Huang and more!
November 8, 2025 at 12:38 AM
Save the date for #GIA2026 (Nov. 5-6, 2026) which will feature free #glycotime talks by @carolynbertozzi.bskyverified.social , Dr. Mia Huang and more!
Reposted by Mathieu Decloquement
Amazing #glycotime immune research on display at GIA2025. Come join us at this free hybrid event and watch talk by some of the best in the field. Register here
We’re thrilled to introduce GIA2025 Trainee Invited Speaker Dr. Jim Paulson, Professor Emeritus in the Department of Immunology and Microbiology at The Scripps Research Institute in La Jolla, CA who’ll talk on the roles of inhibitory Siglecs in regulation of immune responses! #GIA2025 #glycotime
October 29, 2025 at 1:21 AM
Amazing #glycotime immune research on display at GIA2025. Come join us at this free hybrid event and watch talk by some of the best in the field. Register here
Reposted by Mathieu Decloquement
Register for virtual or in person attendance for FREE at forms.gle/GGXwhBiRPgA9... #glycotime
forms.gle
October 27, 2025 at 10:41 PM
Register for virtual or in person attendance for FREE at forms.gle/GGXwhBiRPgA9... #glycotime
Reposted by Mathieu Decloquement
Reminder that the deadline to submit an abstract to be considered for a 15 minute talk at GIA2025 is tonight! Don't miss out on presenting your glyco research and the opportunity to have lunch with Dr. Jim Paulson, our trainee-invited speaker! Link to submit: forms.gle/BdDTRsdXmTP9.... #GIA2025
forms.gle
October 27, 2025 at 10:48 PM
Reminder that the deadline to submit an abstract to be considered for a 15 minute talk at GIA2025 is tonight! Don't miss out on presenting your glyco research and the opportunity to have lunch with Dr. Jim Paulson, our trainee-invited speaker! Link to submit: forms.gle/BdDTRsdXmTP9.... #GIA2025
Reposted by Mathieu Decloquement
We’re excited to invite you to the @giaglyco.bsky.social GIA2025 Symposium on Thursday and Friday, November 6–7. Registration is free and the event will take place in person and virtually for those joining online. glyco-alberta.ca/gia2025/ Come get the latest #Glycogang swag!
GIA2025
Join us for our fourth annual symposium, a celebration of knowledge and innovation in the field of glycoscience! Whether you’re an aspiring scientist or a seasoned researcher…
glyco-alberta.ca
October 6, 2025 at 4:57 PM
We’re excited to invite you to the @giaglyco.bsky.social GIA2025 Symposium on Thursday and Friday, November 6–7. Registration is free and the event will take place in person and virtually for those joining online. glyco-alberta.ca/gia2025/ Come get the latest #Glycogang swag!
Reposted by Mathieu Decloquement
🧪 Come join us for free #glycotime Register here for hybrid or in person attendance glyco-alberta.ca/gia2025/
The countdown is on! With GIA2025 less than 3 weeks away, we’d like to introduce our Keynote Speakers that we will have the privilege of hosting this year. First is Dr. Sriram Neelameghan from the University at Buffalo whose lab studies the area of Systems Glycobiology. @neel-lab.bsky.social
October 20, 2025 at 11:05 PM
🧪 Come join us for free #glycotime Register here for hybrid or in person attendance glyco-alberta.ca/gia2025/
Reposted by Mathieu Decloquement
🧬Power your research with GlycoNet Integrated Services’ Molecular Glycobiology node at the @ualberta.bsky.social
Offering:
Custom cell & mouse models (CRISPR, transgenics)
Siglec-Fc protein production
Cell engineering & expert support
Explore more services: canadianglycomics.ca/services/
Offering:
Custom cell & mouse models (CRISPR, transgenics)
Siglec-Fc protein production
Cell engineering & expert support
Explore more services: canadianglycomics.ca/services/
July 10, 2025 at 6:01 PM
🧬Power your research with GlycoNet Integrated Services’ Molecular Glycobiology node at the @ualberta.bsky.social
Offering:
Custom cell & mouse models (CRISPR, transgenics)
Siglec-Fc protein production
Cell engineering & expert support
Explore more services: canadianglycomics.ca/services/
Offering:
Custom cell & mouse models (CRISPR, transgenics)
Siglec-Fc protein production
Cell engineering & expert support
Explore more services: canadianglycomics.ca/services/
Reposted by Mathieu Decloquement
🚨 Just published in Mass Spectrometry Reviews! 🚨
Thrilled to share our latest review, summarizing over 20 years of work from the Klassen lab —plus insights from my own PhD research on COIN-nMS, SLOMO-nMS, and charge detection MS.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Thrilled to share our latest review, summarizing over 20 years of work from the Klassen lab —plus insights from my own PhD research on COIN-nMS, SLOMO-nMS, and charge detection MS.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry
Interactions between glycan-binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan i...
analyticalsciencejournals.onlinelibrary.wiley.com
June 30, 2025 at 4:57 PM
🚨 Just published in Mass Spectrometry Reviews! 🚨
Thrilled to share our latest review, summarizing over 20 years of work from the Klassen lab —plus insights from my own PhD research on COIN-nMS, SLOMO-nMS, and charge detection MS.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Thrilled to share our latest review, summarizing over 20 years of work from the Klassen lab —plus insights from my own PhD research on COIN-nMS, SLOMO-nMS, and charge detection MS.
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
Reposted by Mathieu Decloquement
When glycan recognition is linked to immune response, you need fine tuning! 😎
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
June 22, 2025 at 10:42 AM
When glycan recognition is linked to immune response, you need fine tuning! 😎
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
Here ⬇️ we show how human Siglecs act as molecular precision tools, recognising the glycan and also the biological environment (or context) these glycans are found in. A 1/5 #glycotime🧵 ⬇️
doi.org/10.1101/2025...
Reposted by Mathieu Decloquement
🔬Meet Dr. @faezehjame.bsky.social , a postdoc at SFU, studying how sugar molecules influence disease. Working in the Vocadlo lab, she is exploring how sugar molecules and the driving enzymes, glycosyltransferases, are involved in health and disease.
Read: canadianglycomics.ca/trainee-at-g...
Read: canadianglycomics.ca/trainee-at-g...
June 19, 2025 at 4:07 PM
🔬Meet Dr. @faezehjame.bsky.social , a postdoc at SFU, studying how sugar molecules influence disease. Working in the Vocadlo lab, she is exploring how sugar molecules and the driving enzymes, glycosyltransferases, are involved in health and disease.
Read: canadianglycomics.ca/trainee-at-g...
Read: canadianglycomics.ca/trainee-at-g...
Good time at the Summer School in Structural Glycosciences organized by @glyco-alps.bsky.social and @anneimb.bsky.social . Was nice to visit the IBS, ESRF and CERMAV and meet a friendly glyco-community in Grenoble 🏔️
June 19, 2025 at 4:37 PM
Good time at the Summer School in Structural Glycosciences organized by @glyco-alps.bsky.social and @anneimb.bsky.social . Was nice to visit the IBS, ESRF and CERMAV and meet a friendly glyco-community in Grenoble 🏔️
Reposted by Mathieu Decloquement
Great few days in Maynooth for the 16th Jenner Glycobiology & Medicine Symposium. Grateful to have presented my work from the @siglecdude.bsky.social lab, connect with brilliant glyco-scientists, hear inspiring stories of pioneers, and enjoy Irish music & culture. 🇮🇪🎶🍻 #glycotime
June 15, 2025 at 9:59 PM
Great few days in Maynooth for the 16th Jenner Glycobiology & Medicine Symposium. Grateful to have presented my work from the @siglecdude.bsky.social lab, connect with brilliant glyco-scientists, hear inspiring stories of pioneers, and enjoy Irish music & culture. 🇮🇪🎶🍻 #glycotime
Reposted by Mathieu Decloquement
Very excited to share some work the Lab has been working on for a while. A new platform to probe Siglec ligands. Led by an incredible PhD student (Zeinab). Comes out of an ongoing fruitful collaboration with the Derda lab. Very open to feedback! www.biorxiv.org/content/10.1...
An ultrasensitive and modular platform to detect Siglec ligands and control immune cell function
Siglecs are immunomodulatory receptors that regulate immune cell function. A fundamental challenge in studying Siglec-ligand interactions is the low affinity of Siglecs for their ligands. Inspired by ...
www.biorxiv.org
June 14, 2025 at 9:05 PM
Very excited to share some work the Lab has been working on for a while. A new platform to probe Siglec ligands. Led by an incredible PhD student (Zeinab). Comes out of an ongoing fruitful collaboration with the Derda lab. Very open to feedback! www.biorxiv.org/content/10.1...
Reposted by Mathieu Decloquement
New work on the structure of Siglec-10. Great collaboration that was solidified with a visit to Spain last year with fantastic discussions with June Ereno-Orbea and Jesus Jimenez-Barbero. Nice contributions on modeling by @elisafadda.bsky.social.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
The unique molecular recognition features of Siglec-10: structural insights into sialoglycan and antibody interactions
Siglec-10 is a sialic acid-binding immunoglobulin-like lectin implicated in immune regulation, yet its molecular basis for ligand recognition and functional role in immune modulation remain poorly def...
www.biorxiv.org
June 12, 2025 at 1:26 PM
New work on the structure of Siglec-10. Great collaboration that was solidified with a visit to Spain last year with fantastic discussions with June Ereno-Orbea and Jesus Jimenez-Barbero. Nice contributions on modeling by @elisafadda.bsky.social.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Amazing week at #Glyco27 with top glycoscientists from around the world! 🌎🧪
Grateful for the opportunity to share my research from the @siglecdude.bsky.social Lab 📊🙌
Last day — don’t forget to grab your fav monosaccharide at the @giaglyco.bsky.social booth! 😎
#glycotime @glyconet.bsky.social
Grateful for the opportunity to share my research from the @siglecdude.bsky.social Lab 📊🙌
Last day — don’t forget to grab your fav monosaccharide at the @giaglyco.bsky.social booth! 😎
#glycotime @glyconet.bsky.social
May 30, 2025 at 3:08 PM
Amazing week at #Glyco27 with top glycoscientists from around the world! 🌎🧪
Grateful for the opportunity to share my research from the @siglecdude.bsky.social Lab 📊🙌
Last day — don’t forget to grab your fav monosaccharide at the @giaglyco.bsky.social booth! 😎
#glycotime @glyconet.bsky.social
Grateful for the opportunity to share my research from the @siglecdude.bsky.social Lab 📊🙌
Last day — don’t forget to grab your fav monosaccharide at the @giaglyco.bsky.social booth! 😎
#glycotime @glyconet.bsky.social
Reposted by Mathieu Decloquement
We’re kicking off the first full day at Glyco27! Be sure to catch GIA’s Trainee co-chair Mathieu Decloquement’s (mathd34.bsky.social) talk on Tuesday from 5-5:15pm in Hall A during the Cancer session. His talk will be on Deciphering Siglec ligands in cancer to improve immunotherapy. #Glyco27
May 26, 2025 at 3:50 PM
We’re kicking off the first full day at Glyco27! Be sure to catch GIA’s Trainee co-chair Mathieu Decloquement’s (mathd34.bsky.social) talk on Tuesday from 5-5:15pm in Hall A during the Cancer session. His talk will be on Deciphering Siglec ligands in cancer to improve immunotherapy. #Glyco27
Reposted by Mathieu Decloquement
It’s been great to hear from Dr. Noortje de Haan, Dr. Stacy Malaker, and Dr. Manfred Wuhrer at the Spectrometry / Glycoproteomics Workshop this morning at #Glyco27!
May 25, 2025 at 7:49 PM
It’s been great to hear from Dr. Noortje de Haan, Dr. Stacy Malaker, and Dr. Manfred Wuhrer at the Spectrometry / Glycoproteomics Workshop this morning at #Glyco27!
Reposted by Mathieu Decloquement
This afternoon’s #Glycobioinformatics Workshop at #Glyco27 is underway!
Led by Dr. Kiyoko Aoki-Kinoshita and Dr. Frederique Lisacek, participants are diving into the latest tools and innovations driving progress in glyco-data analysis. Great turnout and discussion happening now!
Led by Dr. Kiyoko Aoki-Kinoshita and Dr. Frederique Lisacek, participants are diving into the latest tools and innovations driving progress in glyco-data analysis. Great turnout and discussion happening now!
May 25, 2025 at 10:01 PM
This afternoon’s #Glycobioinformatics Workshop at #Glyco27 is underway!
Led by Dr. Kiyoko Aoki-Kinoshita and Dr. Frederique Lisacek, participants are diving into the latest tools and innovations driving progress in glyco-data analysis. Great turnout and discussion happening now!
Led by Dr. Kiyoko Aoki-Kinoshita and Dr. Frederique Lisacek, participants are diving into the latest tools and innovations driving progress in glyco-data analysis. Great turnout and discussion happening now!
Reposted by Mathieu Decloquement
Specificity in glycosylation! Have you ever wondered why some glycosyltransferases recognize glycoproteins, some glycolipids, and some both? Together with @kmikolajczyk.bsky.social and @rkaczmarekdr.bsky.social, we try to answer that complicated question.
#glycotime
tinyurl.com/5b6kxhp3
#glycotime
tinyurl.com/5b6kxhp3
May 7, 2025 at 9:13 AM
Specificity in glycosylation! Have you ever wondered why some glycosyltransferases recognize glycoproteins, some glycolipids, and some both? Together with @kmikolajczyk.bsky.social and @rkaczmarekdr.bsky.social, we try to answer that complicated question.
#glycotime
tinyurl.com/5b6kxhp3
#glycotime
tinyurl.com/5b6kxhp3
Reposted by Mathieu Decloquement
🚨 Don't miss one of the top #glycotime events of the year! The 27th International Glycoconjugate Symposium (Glyco27) and 8th Canadian Glycomics Symposium jointly hosted by the IGO and @glyconet.bsky.social will take place in Edmonton, AB 🇨🇦, from 25-30th of May 2025 🌟🍬 Details at www.glyco27.org/en
April 7, 2025 at 9:19 AM
🚨 Don't miss one of the top #glycotime events of the year! The 27th International Glycoconjugate Symposium (Glyco27) and 8th Canadian Glycomics Symposium jointly hosted by the IGO and @glyconet.bsky.social will take place in Edmonton, AB 🇨🇦, from 25-30th of May 2025 🌟🍬 Details at www.glyco27.org/en