Maria Gutierrez-Arcelus
@mariagtac.bsky.social
Investigating genetic mechanisms of immune-mediated diseases | faculty at Boston Children's Hospital
Reposted by Maria Gutierrez-Arcelus
All data are available in a user-friendly interactive Shiny app that you can use to search your favorite genes across conditions (link in the Methods section).
May 28, 2025 at 4:06 PM
All data are available in a user-friendly interactive Shiny app that you can use to search your favorite genes across conditions (link in the Methods section).
Reposted by Maria Gutierrez-Arcelus
I’m excited to share my latest work with Marcella Franco, @mariagtac.bsky.social, and an amazing team. We used multi-omics to dissect key pathways of B cell activation, exploring gene programs, splicing, cell fates, and disease heritability in activated B cells.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
May 28, 2025 at 4:00 PM
I’m excited to share my latest work with Marcella Franco, @mariagtac.bsky.social, and an amazing team. We used multi-omics to dissect key pathways of B cell activation, exploring gene programs, splicing, cell fates, and disease heritability in activated B cells.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Reposted by Maria Gutierrez-Arcelus
I'm excited to share I'll be starting a faculty position at Boston Children's Hospital in the Computational Health Informatics Program (CHIP) this October!!
June 2, 2025 at 11:40 PM
I'm excited to share I'll be starting a faculty position at Boston Children's Hospital in the Computational Health Informatics Program (CHIP) this October!!
Do you have an interest in B cells and immune-mediated diseases? We generated a multiomics resource of human B cell activation and showed its utility for elucidating disease mechanisms. Check out our manuscript led by @vitoraguiar.bsky.social and Marcella Franco: www.medrxiv.org/content/10.1...
A multi-omics resource of B cell activation reveals genetic mechanisms for immune-mediated diseases
Most genetic variants that confer risk of complex immune-mediated diseases (IMD) affect gene regulation in specific cell types. Their target genes and focus cell types are often unknown, partially bec...
www.medrxiv.org
May 24, 2025 at 4:33 PM
Do you have an interest in B cells and immune-mediated diseases? We generated a multiomics resource of human B cell activation and showed its utility for elucidating disease mechanisms. Check out our manuscript led by @vitoraguiar.bsky.social and Marcella Franco: www.medrxiv.org/content/10.1...
Reposted by Maria Gutierrez-Arcelus
I am truly honored to have been awarded a Career Development Fellowship by Boston Children’s.
I am grateful to my mentors and collaborators for all the support.
Looking forward to bridging statistical and population genetics with the clinic to fight autoimmune diseases.
I am grateful to my mentors and collaborators for all the support.
Looking forward to bridging statistical and population genetics with the clinic to fight autoimmune diseases.
May 16, 2025 at 10:20 AM
I am truly honored to have been awarded a Career Development Fellowship by Boston Children’s.
I am grateful to my mentors and collaborators for all the support.
Looking forward to bridging statistical and population genetics with the clinic to fight autoimmune diseases.
I am grateful to my mentors and collaborators for all the support.
Looking forward to bridging statistical and population genetics with the clinic to fight autoimmune diseases.
Reposted by Maria Gutierrez-Arcelus
Looking forward reading another interesting preprint from @vitoraguiar.bsky.social and @mariagtac.bsky.social. Well done!
A multi-omics resource of B cell activation reveals genetic mechanisms for immune-mediated diseases https://www.medrxiv.org/content/10.1101/2025.05.22.25328104v1
May 23, 2025 at 9:49 PM
Looking forward reading another interesting preprint from @vitoraguiar.bsky.social and @mariagtac.bsky.social. Well done!
Reposted by Maria Gutierrez-Arcelus
Thrilled to share my 1st PhD's 1st publication at
@liigh-unam.bsky.social. Anecdotally it is also my 1st paper as corresponding author from my group / the "Paloegenomics and Evolutionary Biology". shorturl.at/VumOq Let us know what you think about it.
@liigh-unam.bsky.social. Anecdotally it is also my 1st paper as corresponding author from my group / the "Paloegenomics and Evolutionary Biology". shorturl.at/VumOq Let us know what you think about it.
Ancient DNA HLA typing reveals significant shifts in frequency in Europe since the Neolithic - Scientific Reports
Computational HLA typing has surged as a cost-effective strategy to uncover questions regarding the evolution of the HLA system, enabling immunogenic characterization from ancient DNA (aDNA) data. Nev...
shorturl.at
February 21, 2025 at 2:50 AM
Thrilled to share my 1st PhD's 1st publication at
@liigh-unam.bsky.social. Anecdotally it is also my 1st paper as corresponding author from my group / the "Paloegenomics and Evolutionary Biology". shorturl.at/VumOq Let us know what you think about it.
@liigh-unam.bsky.social. Anecdotally it is also my 1st paper as corresponding author from my group / the "Paloegenomics and Evolutionary Biology". shorturl.at/VumOq Let us know what you think about it.
Reposted by Maria Gutierrez-Arcelus
Congratulations to @soniagr.bsky.social, rytenlab.com team, et al for this project re-analyzing #GTEx human gene expression data uniformly re-processed with #recount3
It was a pleasure working with Sonia G & Mina Ryten
doi.org/10.1038/s414...
@bioconductor.bsky.social @lieberinstitute.bsky.social
It was a pleasure working with Sonia G & Mina Ryten
doi.org/10.1038/s414...
@bioconductor.bsky.social @lieberinstitute.bsky.social
New in @naturecomms.bsky.social: I'm thrilled to share with you our latest work that applies #srRNAseq to understand splicing accuracy across human introns, tissues and in the context of ageing and neurodegeneration www.nature.com/articles/s41...
Splicing accuracy varies across human introns, tissues, age and disease - Nature Communications
Inaccuracies in RNA splicing may play a significant role in aging and disease. Here, the authors present a comprehensive characterization of splicing accuracy across over 14,000 human samples, offerin...
www.nature.com
January 28, 2025 at 8:54 PM
Congratulations to @soniagr.bsky.social, rytenlab.com team, et al for this project re-analyzing #GTEx human gene expression data uniformly re-processed with #recount3
It was a pleasure working with Sonia G & Mina Ryten
doi.org/10.1038/s414...
@bioconductor.bsky.social @lieberinstitute.bsky.social
It was a pleasure working with Sonia G & Mina Ryten
doi.org/10.1038/s414...
@bioconductor.bsky.social @lieberinstitute.bsky.social