MANDRAKE
banner
mandrakelab.bsky.social
MANDRAKE
@mandrakelab.bsky.social
MANchester DRug Analysis & Knowledge Exchange @ Manchester Metropolitan University. Award winning partnership working to deliver effective harm reduction through excellence in science.
⚠️WARNING⚠️ 19 Nov 2025

Multiple samples of ketamine circulating in #Manchester have been confirmed, by our lab, to be contaminated with medetomidine

The GM Drugs Early Warning System has subsequently issued the following warning

If unwell please seek medical attention
November 19, 2025 at 4:26 PM
⚠️WARNING⚠️ 23 Oct 2025

With two separate, tragic deaths in #Manchester last week, both involving young women and both believed to have taken #MDMA powder/crystals GMCA have issued this alert via the GM Drugs Early Warning System.

If unwell please seek medical attention.
October 23, 2025 at 6:54 PM
⛔️CAUTION!⛔️ 23 Aug 2025

Back-of-house substance testing by @MANDRAKE_LAB has found multiple samples of synthetic #cathinone 4-chloromethcathinone (4-CMC) circulating at Manchester Pride Festival.

If unwell please seek medical attention.
August 23, 2025 at 9:58 PM
Reposted by MANDRAKE
💥BREAKING NEWS💥

Many congratulations to Emily Dawber on conferment of her #Masters today. Well done!

Dr RyanMewis, Dr Jim Pritchett & I are extremely proud of your hard work both in your research and for your dedication to @mandrakelab.bsky.social’s harm reduction activities.
May 16, 2025 at 5:55 AM
⛔️CAUTION!⛔️ 03 May 2025

Multiple examples of high content #Ecstasy tablets analytically confirmed by @MANDRAKE_LAB, to contain #MDMA (254 - 264 mg/tablet) = to 2½ - 3x the common oral dose circulating in #Manchester.

If unwell please seek medical attention.
May 5, 2025 at 12:53 PM
💥TESTING DATA💥 Mar 2025

A quick snapshot of recent bsky.app/profile/mand... testing data, of frequently encountered “Ecstasy” pill/tablet types, from across Greater Manchester’s NTE venues.

MDMA (as salt) content was determined by GCMS using primary reference std & expressed in mg/tab.
March 31, 2025 at 4:33 PM
⚠️WARNING!⚠️ 29 Mar 25

Multiple samples of beige powder, potentially mis-sold as MDMA, confirmed by @MANDRAKE_LAB, to contain synthetic cathinone, 4F-α-PVP, in #Manchester

Not much known about this substance but has been implicated fatalities.

If unwell seek medical attention.
March 30, 2025 at 8:43 AM
⛔️CAUTION!⛔️ 27 Mar 2025

Multiple, Blue “Moncler” embossed #Ecstasy tablets analytically confirmed by @MANDRAKE_LAB, to contain #MDMA (average: 277 mg/tablet) = to 3x the common oral dose circulating in #Manchester.

If unwell please seek medical attention.
March 30, 2025 at 8:42 AM
💥DRUG FOCUS REPORT💥

The GMTRENDS focus report on “ketamine” trends, covering 2023/24, is available (for free) online.

This collaborative work, led by by @MMUOutofit, includes detailed chemical analysis by our team of scientists.

Link (free): gmtrends.mmu.ac.uk/wp-content/u...
gmtrends.mmu.ac.uk
February 18, 2025 at 9:02 AM
Reposted by MANDRAKE
💥NEW RESEARCH PAPER💥

Our collaborative work led by Ryan Mewis w/ Matthew Hulme, Jack Marron, Stuart Langley & Sophie Benjamin on the synthesis & crystal structures of 5 fluorinated diphenidine derivatives is available (free) online

Link: journals.iucr.org/e/issues/202...
February 17, 2025 at 7:28 PM
Reposted by MANDRAKE
💥NEW RESEARCH PAPER💥

Our collaborative work w/ Shimadzu, Phenomenex and Greater #Manchester Police on the #enantiomeric separation of #diphenidine-derived #NPS by polar organic chiral #HPLC
is available online (pre-proof) in J. Pharm. Biomed. Analysis 👇

www.sciencedirect.com/science/arti...
Guilty by Dissociation: Part C: Enantiomeric Separation of Diphenidine-Derived New Psychoactive Substances (NPS) by Polar Organic Chiral High Performance Liquid Chromatography (HPLC) on Polysaccharide...
This study describes a simple and practical HPLC analysis for the direct enantiomeric separation of a range of 32 novel diphenidine derived psychoacti…
www.sciencedirect.com
February 7, 2025 at 2:07 PM
💥BREAKING!💥 15 Jan 2025

Our Director @sutcliffeob.bsky.social speaks on BBC Radio 4 “Cannabis Kids: The parents breaking the law to help their children with epilepsy” about how we have been working w/ stakeholders & industry to understand the UK cannabis market.

www.bbc.co.uk/programmes/m...
BBC Radio 4 - File on 4 Investigates, Cannabis Kids: The parents breaking the law to help their children with epilepsy
An investigation reveals children are being given illegal cannabis to treat epilepsy.
www.bbc.co.uk
January 15, 2025 at 9:14 PM
⚠️WARNING!⚠️ 19 Dec 2024

Following testing by our scientists, a #harmreduction #warning, has been issued by #Greater #Manchester Drugs Early Warning System

Important #medical & #welfare guidance for #nitazene #intoxication

Stay safe and if unwell please seek medical attention
December 19, 2024 at 11:15 AM
💥BREAKING!💥 7 Dec 2024

@robralphs.bsky.social and @sutcliffeob.bsky.social #Spice (#SCRAs, synthetic cannabinoids) “Primer”, first published in The Conversation in 2016, is the THIRD most read article published by Man Met Uni and just received >900,000 reads! theconversation.com/what-is-spic...
What is Spice and why is the drug so dangerous?
New psychoactive substances, same problematic users.
theconversation.com
December 7, 2024 at 8:47 AM
💥REQUEST💥 28 Nov 24

Please complete the 2024/25 Students, Alcohol and Drug Survey and retweet it to your social networks

This survey is via @sosukcharity & available here:

online1.snapsurveys.com/interview/b1...

This is YOUR opportunity to shape harm reduction and awareness on UK campus’
Starting survey...
online1.snapsurveys.com
November 28, 2024 at 7:53 PM
💥BREAKING!💥 22 Nov 2024

We’re extremely proud to announce that we have received additional PUBLIC FUNDING for our harm reduction work!

The team are honoured to EXPAND our nationally-recognised harm reduction partnerships, across the UK, and now safeguard the residents in Newcastle-upon-Tyne.
November 22, 2024 at 7:29 PM
Do YOU know the DANGERS of synthetic cannabinoids or "Spice"???

Would you like to know more?

Read our short (1 min read) PRIMER "What is Spice" (theconversation.com/what-is-spic...) and get the lowdown and keep yourself and others safe!
November 19, 2024 at 7:14 PM
Through our research, we strive to tackle inequalities & enhance people's lives.

Read Ralphs & Sutcliffe @sutcliffeob.bsky.social #Spice “Primer” in The Conversation here: theconversation.com/what-is-spic...

Also read our focus report on #THC vapes here: gmtrends.mmu.ac.uk/wp-content/u...
November 17, 2024 at 3:18 PM