LNCD
lncdpitt.bsky.social
LNCD
@lncdpitt.bsky.social
410 followers 820 following 26 posts
Laboratory of Neurocognitive Development under the mentorship of Dr. Beatriz Luna | University of Pittsburgh
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Highlights:
- Ultra-high-field 7 T fMRI was used to segment amygdala nuclei
- Fronto-amygdala functional connections develop along distinct trajectories
- Age-related connections relate to affective and cognitive control
- Amygdala nuclei exhibit developmental and functional specialization
NEW PAPER ALERT! Check out the recent work of @amarojha.bsky.social "Human amygdala nuclei show distinct developmental trajectories from adolescence to adulthood in functional integration with prefrontal circuitry" now out in Cell Reports! www-sciencedirect-com.pitt.idm.oclc.org/science/arti...
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Reposted by LNCD
Find us now on insta ! @lncd_pitt
The posters are underway! Go check them out #flux2025
Flux day 2! Starting it off with a flash talk by @shanemckeon.bsky.social and then 4 posters! #Flux2025
Find us now on insta ! @lncd_pitt
Go Victoria Go! First day of flux is wrapping up with an awesome poster session! #Flux2025
Happy Flux day 1! Check out Victoria Dionisos’ poster (number T12) today on Developmental Interactions Between Local and Long-Range Connectivity, Gray Matter Microstructure, and Inhibitory Control From Adolescence to Young Adulthood #Flux2025
Come check out the LNCD lab at #flux2025 !! Cant wait to see you all in Dublin !
Reposted by LNCD
How does the human brain coordinate hierarchical cortical development? Our work in Nature Neuroscience identifies a role for thalamocortical structural connectivity in the expression of hierarchical periods of cortical plasticity & environmental receptivity in youth 🧵 www.nature.com/articles/s41...
Poster session 2 is underway at Pitt psychiatry day! Go check out @shanemckeon.bsky.social @amarojha.bsky.social Dan Ashley Destiny and Piya!
Happy Psychiatry Day! Check out our labs work at soldiers and sailors at Pitt ! First up this morning we have Abby ! A first year BioE PhD student @abbybeatty.bsky.social
@nicolenelson.bsky.social would love to be added to your starter pack!
After searching through bluesky, I realized there wasnt a starter pack for Adolescent Neurocognitive Development (at least I couldnt find one), so decided to start one! Please help me in adding members of the awesome community

go.bsky.app/R8mzr8W
This is the bluesky account for the Laboratory of Neurocognitive Development under Dr. Breatiz Luna. We would love to be added !
@nataliebrito.bsky.social Hi Dr. Brito! This is the bluesky account for the Laboratory of Neurocognitive Development under Dr. Breatiz Luna. We would love to be added to the developmental psych starter pack!
Our findings highlight adolescence as a critical period for functional specialization in the brain. As local connectivity decreases, circuits become more independent, higher-dimensional, & optimized for cognition. #Neuroimaging
Understanding these developmental shifts is key for studying mental health disorders that emerge in adolescence (e.g., schizophrenia, mood disorders). Future work should explore:
🔹 Synaptic pruning mechanisms
🔹 Neural signal dimensionality
🔹 Longitudinal effects on cognition
These changes may:
✅ Increase information complexity in neural coding
✅ Support better cognitive flexibility & memory
✅ Reduce variability in motor & executive tasks
Adolescence is when the brain optimizes for efficiency over redundancy!
We found ReHo decreases in networks involved in cognitive control & motor regulation, like:
🔹 Cingulo-opercular network (CON) → stabilizing goal-directed actions
🔹 Somatomotor networks → refining movement control
🔹 Frontoparietal networks → supporting executive function
Cortical circuits showed increasing segregation, meaning nearby brain areas became more independent. This aligns with:
🔹 Synaptic pruning & refining neural connections
🔹 Increased signal fidelity & computational capacity
🔹 More efficient cognitive processing
Our longitudinal study (N=134, ages 10–31) found that through adolescence:
🔹 Local functional connectivity decreases
🔹 Brain circuits become more specialized
🔹 Coding capacity & efficiency increase
This supports the shift toward adult-like cognition.