Krishna Reddy
@krishnareddy.bsky.social
84 followers
120 following
18 posts
Assistant Professor, University of South Florida. Membrane protein structure-function, engineering, evolution. My beard hides several personality flaws.
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Krishna Reddy
@krishnareddy.bsky.social
· Sep 12
Krishna Reddy
@krishnareddy.bsky.social
· Sep 12
Krishna Reddy
@krishnareddy.bsky.social
· Sep 12
A structural window into the evolution of secondary transport mechanisms
Nature Structural & Molecular Biology - Protein sequence signatures suggest that eons ago, a bacterial glutamate transporter lost its sodium coupling to make way for a shift to proton coupling....
rdcu.be
Krishna Reddy
@krishnareddy.bsky.social
· Sep 12
Evolutionary analysis reveals the origin of sodium coupling in glutamate transporters - Nature Structural & Molecular Biology
Reddy et al. used ancestral protein reconstruction, cryo-electron microscopy and functional assays to elucidate how a secondary active transporter evolved to harness the energy of sodium gradients to ...
go.nature.com