Katharina Lichter
@klichter.bsky.social
Synaptic Physiologist & MD. PostDoc with P. Jonas @istaresearch.bsky.social Investigates nanoscopic structure-function of synapses. Dedicated to hippocampus, bicycles & mountains.
Reposted by Katharina Lichter
Kiss, shrink, run | Science www.science.org/doi/10.1126/...
Kiss, shrink, run
A unified mechanism directs synaptic vesicle release
www.science.org
October 18, 2025 at 3:23 PM
Kiss, shrink, run | Science www.science.org/doi/10.1126/...
Not clear yet. The authors demonstrate this for glutamatergic synapses in dissociated hippocampal neuron cultures.
October 20, 2025 at 7:53 PM
Not clear yet. The authors demonstrate this for glutamatergic synapses in dissociated hippocampal neuron cultures.
Original paper: doi.org/10.1126/scie...
“Kiss-shrink-run” unifies mechanisms for synaptic vesicle exocytosis and hyperfast recycling
Synaptic vesicle (SV) exocytosis underpins neuronal communication, yet its nanoscale dynamics remain poorly understood owing to limitations in visualizing rapid events in situ. Here, we used optogenet...
doi.org
October 19, 2025 at 1:46 PM
Original paper: doi.org/10.1126/scie...
Kiss, Shrink, Run ⛹🏻♀️ New Perspective in @science.org about one of my favourite topics: how synapses and their tiny vesicles communicate in the brain. Chang-Lu Tao and colleagues reveal a previously unknown pathway for vesicle release. Read more here: doi.org/10.1126/scie... @istaresearch.bsky.social
Kiss, shrink, run
A unified mechanism directs synaptic vesicle release
doi.org
October 19, 2025 at 1:46 PM
Kiss, Shrink, Run ⛹🏻♀️ New Perspective in @science.org about one of my favourite topics: how synapses and their tiny vesicles communicate in the brain. Chang-Lu Tao and colleagues reveal a previously unknown pathway for vesicle release. Read more here: doi.org/10.1126/scie... @istaresearch.bsky.social
Congratulations!
September 15, 2025 at 11:14 AM
Congratulations!
Congratulations!
September 4, 2025 at 12:02 PM
Congratulations!
Thanks for the great opportunity to participate @istaustria-iof.bsky.social 🍩🧠💡
August 28, 2025 at 9:13 AM
Thanks for the great opportunity to participate @istaustria-iof.bsky.social 🍩🧠💡
Reposted by Katharina Lichter
We are delighted and very satisfied with a extremely smooth installation of the @abberior.rocks Mirava Polyscope, by 2 fantastic engineers. Our new ‘imaging soldier’ is equipped with 2- and 3D STED, MINDLUX, adaptive optics, lifetime imaging, matrix detectors and options for spectral imaging.
August 27, 2025 at 2:55 PM
We are delighted and very satisfied with a extremely smooth installation of the @abberior.rocks Mirava Polyscope, by 2 fantastic engineers. Our new ‘imaging soldier’ is equipped with 2- and 3D STED, MINDLUX, adaptive optics, lifetime imaging, matrix detectors and options for spectral imaging.
Reposted by Katharina Lichter
Reposted by Katharina Lichter
The @erc.europa.eu awards Advanced Grants to “active researchers who have a track-record of significant research achievements.” ISTA could now secure a quadruple success in the most recent call for these prestigious European grants. #ERCAdG
June 17, 2025 at 10:03 AM
The @erc.europa.eu awards Advanced Grants to “active researchers who have a track-record of significant research achievements.” ISTA could now secure a quadruple success in the most recent call for these prestigious European grants. #ERCAdG
Reposted by Katharina Lichter
We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...
Memory by a thousand rules: Automated discovery of functional multi-type plasticity rules reveals variety & degeneracy at the heart of learning
Synaptic plasticity is the basis of learning and memory, but the link between synaptic changes and neural function remains elusive. Here, we used automated search algorithms to obtain thousands of str...
www.biorxiv.org
June 2, 2025 at 6:50 PM
We just pushed “Memory by a 1000 rules” onto bioRxiv, where we use clever #ML to find #plasticity quadruplets (EE, EI, IE, II) that learn basic stability in spiking nets. Why is it cool? We find 1000s!! of solutions, and they don’t just stabilise. They #memorise! www.biorxiv.org/content/10.1...
Reposted by Katharina Lichter
Curious about the latest news on how RGP lineages generate cortical neuronal diversity? Don't miss our new review from @HippenmeyerLab written by @fabripipicelli.bsky.social and myself www.sciencedirect.com/science/arti...
How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex
The cerebral cortex is arguably the most complex organ in humans. The cortical architecture is characterized by a remarkable diversity of neuronal and…
www.sciencedirect.com
May 22, 2025 at 7:24 PM
Curious about the latest news on how RGP lineages generate cortical neuronal diversity? Don't miss our new review from @HippenmeyerLab written by @fabripipicelli.bsky.social and myself www.sciencedirect.com/science/arti...
Reposted by Katharina Lichter
www.sciencedirect.com/science/arti...
Our new review in Current Opinion in Neurobiology is out! "How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex"
Our new review in Current Opinion in Neurobiology is out! "How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex"
How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex
The cerebral cortex is arguably the most complex organ in humans. The cortical architecture is characterized by a remarkable diversity of neuronal and…
www.sciencedirect.com
May 20, 2025 at 12:00 PM
www.sciencedirect.com/science/arti...
Our new review in Current Opinion in Neurobiology is out! "How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex"
Our new review in Current Opinion in Neurobiology is out! "How radial glia progenitor lineages generate cell-type diversity in the developing cerebral cortex"
@chaichinta.bsky.social impressive results!!! 🤩
May 18, 2025 at 6:30 PM
@chaichinta.bsky.social impressive results!!! 🤩
Enjoy and best from Vienna :)
May 18, 2025 at 12:32 PM
Enjoy and best from Vienna :)
Hi Sam, very interesting thoughts. If you would look further downstream, e.g. towards the presynaptic active zones and the direct release of vesicles in synaptic terminals, we know that these active zone protein composition might be specific for some synapses, even within one organism.
March 17, 2025 at 3:20 AM
Hi Sam, very interesting thoughts. If you would look further downstream, e.g. towards the presynaptic active zones and the direct release of vesicles in synaptic terminals, we know that these active zone protein composition might be specific for some synapses, even within one organism.
Hi Tanja, thanks for sharing your insights! Sorry that you had such an experience. Katharina
March 2, 2025 at 12:37 PM
Hi Tanja, thanks for sharing your insights! Sorry that you had such an experience. Katharina
Sehr informativ! Well done!
March 1, 2025 at 12:18 PM
Sehr informativ! Well done!
Hi Antje, cool work! On my reading list :) congrats!
February 7, 2025 at 7:27 PM
Hi Antje, cool work! On my reading list :) congrats!
Congrats, super cool work!
January 10, 2025 at 10:36 AM
Congrats, super cool work!
Reposted by Katharina Lichter
🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
January 10, 2025 at 9:00 AM
🔬 Ever wondered how therapeutic antibodies work?
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
3D LLS-TDI-DNA-PAINT and live-cell LLS microscopy allow decoding of the molecular interplay of endogenous CD20 on B cells with therapeutic antibodies.
📄 Read more: www.science.org/doi/10.1126/...
I really appreciate @neuroandbeyond.bsky.social - great topics, always a pleasure to listen!
January 8, 2025 at 10:19 PM
I really appreciate @neuroandbeyond.bsky.social - great topics, always a pleasure to listen!