Justin Rudd
jrudd35.bsky.social
Justin Rudd
@jrudd35.bsky.social
MD/PhD Student. CUSOM. Skin Biology
Reposted by Justin Rudd
Awesome story about #lamellar bodies, unique #keratinocyte #organelles secreted as the “mortar” of the #epidermis that prevents our #skin from drying out. We were ecstatic to play a small part. Especially cool since the organelle was discovered decades ago by Dr Odland at @uwdermatology.bsky.social.
July 28, 2025 at 7:22 AM
So thrilled to finally share our story describing Flower as a regulator of lamellar body (LB) trafficking in the epidermis!
www.nature.com/articles/s41...
Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier - Nature Communications
The barrier function of skin epidermis requires polarized secretion of lamellar bodies towards the body surface. Here, Rudd et al. identify Flower (FWE) as a novel regulator of lamellar body trafficki...
www.nature.com
July 28, 2025 at 1:19 AM