The Journal of Physiology
@jphysiol.bsky.social
The Journal of Physiology publishes original research in all areas of physiology and pathophysiology that illustrates new physiological principles or mechanisms.
In this study investigating harnessing #metabolic control for synaptic stability, Daniele Ferrante et al. found that REST/NRSF links glycolytic inhibition to excitatory #neurotransmission 🧠 🔬
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 28, 2025 at 4:01 PM
In this study investigating harnessing #metabolic control for synaptic stability, Daniele Ferrante et al. found that REST/NRSF links glycolytic inhibition to excitatory #neurotransmission 🧠 🔬
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Hironori Watanabe et al. observed that reduced dietary intake induces body fluid #hypotonicity via alterations in water and energy #metabolism 🍽️ 🔋
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 28, 2025 at 2:02 PM
Hironori Watanabe et al. observed that reduced dietary intake induces body fluid #hypotonicity via alterations in water and energy #metabolism 🍽️ 🔋
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Jin-Su Kim & Eui-Young Lee examine post-exercise hot water immersion as a potential lifestyle strategy to maximize vascular health in this #JournalClub based on the work of Steward et al. (2025) ✍️ 💭
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 28, 2025 at 12:01 PM
Jin-Su Kim & Eui-Young Lee examine post-exercise hot water immersion as a potential lifestyle strategy to maximize vascular health in this #JournalClub based on the work of Steward et al. (2025) ✍️ 💭
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Ingo H. Greger and Jake F. Watson of mrclmb.bsky.social observed that ‘Mini analysis’ misrepresents changes in #synaptic properties due to incomplete #event detection✍️ 🔎
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 27, 2025 at 4:03 PM
Ingo H. Greger and Jake F. Watson of mrclmb.bsky.social observed that ‘Mini analysis’ misrepresents changes in #synaptic properties due to incomplete #event detection✍️ 🔎
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Maja Lozic et al. observed reduced #osmoresponsiveness in magnocellular #neuroendocrine neurones during chronic salt-loading 🧠 🔎
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 27, 2025 at 2:03 PM
#Research by Maja Lozic et al. observed reduced #osmoresponsiveness in magnocellular #neuroendocrine neurones during chronic salt-loading 🧠 🔎
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Abderrezak Bouchama offers this #Opinion on redefining human heat limits by integrating molecular and evolutionary physiology 💭 🌡️
🔗 Access the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 27, 2025 at 12:01 PM
Abderrezak Bouchama offers this #Opinion on redefining human heat limits by integrating molecular and evolutionary physiology 💭 🌡️
🔗 Access the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Access the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by Maddison Reed of uottawa.ca et al. finds that dual cholinergic and serotonergic #excitatory pathways mediate #oxygen sensing in the zebrafish gill 🐟 🔬
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 26, 2025 at 4:04 PM
#Research by Maddison Reed of uottawa.ca et al. finds that dual cholinergic and serotonergic #excitatory pathways mediate #oxygen sensing in the zebrafish gill 🐟 🔬
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this recent study into the effects of exercise intensity, Cheehoon Ahn et al. examine #molecular responses in #abdominal subcutaneous adipose tissue after a session of endurance exercise 🚴 🔬
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 26, 2025 at 2:03 PM
In this recent study into the effects of exercise intensity, Cheehoon Ahn et al. examine #molecular responses in #abdominal subcutaneous adipose tissue after a session of endurance exercise 🚴 🔬
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🎓EDITOR'S CHOICE🎓
The findings of Gupta of johnshopkinssph.bsky.social et al. establish NHE6 as a contributor to energy metabolism and may suggest strategies for the treatment of low body weight in Christianson Syndrome patients.
🔗: physoc.onlinelibrary.wiley.com/doi/10.1113/...
The findings of Gupta of johnshopkinssph.bsky.social et al. establish NHE6 as a contributor to energy metabolism and may suggest strategies for the treatment of low body weight in Christianson Syndrome patients.
🔗: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 26, 2025 at 1:02 PM
🎓EDITOR'S CHOICE🎓
The findings of Gupta of johnshopkinssph.bsky.social et al. establish NHE6 as a contributor to energy metabolism and may suggest strategies for the treatment of low body weight in Christianson Syndrome patients.
🔗: physoc.onlinelibrary.wiley.com/doi/10.1113/...
The findings of Gupta of johnshopkinssph.bsky.social et al. establish NHE6 as a contributor to energy metabolism and may suggest strategies for the treatment of low body weight in Christianson Syndrome patients.
🔗: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Fahmeed Hyder offers this #Perspective on lactate oxidation for brain energy metabolism based on the work of Koep et al. (2025) 💭 ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 26, 2025 at 12:01 PM
Fahmeed Hyder offers this #Perspective on lactate oxidation for brain energy metabolism based on the work of Koep et al. (2025) 💭 ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Reposted by The Journal of Physiology
I'm particularly proud to have one of my images selected and featured on the cover of the latest issue of @jphysiol.bsky.social
In this issue, you can also read about my latest work on gamma motoneurons! Check it out!!
physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this issue, you can also read about my latest work on gamma motoneurons! Check it out!!
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Our latest issue is now live🎉
Featuring cover art from Sharples et al. (2025) depicting a motoneuron from the lumbar spinal cord of a newborn mouse📷🔬
🔗 Read the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
Featuring cover art from Sharples et al. (2025) depicting a motoneuron from the lumbar spinal cord of a newborn mouse📷🔬
🔗 Read the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
November 25, 2025 at 3:55 PM
I'm particularly proud to have one of my images selected and featured on the cover of the latest issue of @jphysiol.bsky.social
In this issue, you can also read about my latest work on gamma motoneurons! Check it out!!
physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this issue, you can also read about my latest work on gamma motoneurons! Check it out!!
physoc.onlinelibrary.wiley.com/doi/10.1113/...
Raffaele Sarnataro of ox.ac.uk presents this #SymposiumReview examining the #neurobiology of mitochondrial dynamics in #sleep 🧠 💤
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 25, 2025 at 4:02 PM
Raffaele Sarnataro of ox.ac.uk presents this #SymposiumReview examining the #neurobiology of mitochondrial dynamics in #sleep 🧠 💤
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Research by India A. Brooker et al. observed that angiotensin-converting enzyme 2 regulates the #placental response to repeated #hypoxia–reoxygenation insult 💉 🧪
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 25, 2025 at 2:03 PM
#Research by India A. Brooker et al. observed that angiotensin-converting enzyme 2 regulates the #placental response to repeated #hypoxia–reoxygenation insult 💉 🧪
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the study here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Our latest issue is now live🎉
Featuring cover art from Sharples et al. (2025) depicting a motoneuron from the lumbar spinal cord of a newborn mouse📷🔬
🔗 Read the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
Featuring cover art from Sharples et al. (2025) depicting a motoneuron from the lumbar spinal cord of a newborn mouse📷🔬
🔗 Read the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
November 25, 2025 at 1:00 PM
Our latest issue is now live🎉
Featuring cover art from Sharples et al. (2025) depicting a motoneuron from the lumbar spinal cord of a newborn mouse📷🔬
🔗 Read the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
Featuring cover art from Sharples et al. (2025) depicting a motoneuron from the lumbar spinal cord of a newborn mouse📷🔬
🔗 Read the full issue here: physoc.onlinelibrary.wiley.com/toc/14697793...
Ansh Chatterjee presents this #JournalClub on the work of Londei et al. (2025) into the secret life of brain networks ✍️ 🧠
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 25, 2025 at 12:01 PM
Ansh Chatterjee presents this #JournalClub on the work of Londei et al. (2025) into the secret life of brain networks ✍️ 🧠
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Mona Sadek Ali et al. observed that #breastcancer cell-conditioned media inhibit growth and reduce basal and insulin-stimulated #glucose uptake by inhibiting Rac1 activation in rat myotubes 🔬 🧫
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 24, 2025 at 4:03 PM
Mona Sadek Ali et al. observed that #breastcancer cell-conditioned media inhibit growth and reduce basal and insulin-stimulated #glucose uptake by inhibiting Rac1 activation in rat myotubes 🔬 🧫
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this #TopicalReview, Alexandru C. Barboi & Vaughan G. Macefield ask 'The autonomic nervous system: Time for a conceptual reframing?' 🧠 ❓
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 24, 2025 at 2:03 PM
In this #TopicalReview, Alexandru C. Barboi & Vaughan G. Macefield ask 'The autonomic nervous system: Time for a conceptual reframing?' 🧠 ❓
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📖 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📣CALL FOR PAPERS📣
'50 Years of the International Hypoxia Symposia (Hypoxia 2025: Past, Present and the Future)'
🔗 For more information: physoc.onlinelibrary.wiley.com/hub/journal/...
Deadline: Sunday 30th November⏰
'50 Years of the International Hypoxia Symposia (Hypoxia 2025: Past, Present and the Future)'
🔗 For more information: physoc.onlinelibrary.wiley.com/hub/journal/...
Deadline: Sunday 30th November⏰
November 24, 2025 at 1:00 PM
📣CALL FOR PAPERS📣
'50 Years of the International Hypoxia Symposia (Hypoxia 2025: Past, Present and the Future)'
🔗 For more information: physoc.onlinelibrary.wiley.com/hub/journal/...
Deadline: Sunday 30th November⏰
'50 Years of the International Hypoxia Symposia (Hypoxia 2025: Past, Present and the Future)'
🔗 For more information: physoc.onlinelibrary.wiley.com/hub/journal/...
Deadline: Sunday 30th November⏰
This #JournalClub by Laure Haenebalcke & Jeppe F. Vigh-Larsen examines the work of Blervaque et al. (2025) in relation to mean capillary-to-muscle diffusion distance as a limitation for #oxygen uptake and #metabolite exchange
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 24, 2025 at 12:01 PM
This #JournalClub by Laure Haenebalcke & Jeppe F. Vigh-Larsen examines the work of Blervaque et al. (2025) in relation to mean capillary-to-muscle diffusion distance as a limitation for #oxygen uptake and #metabolite exchange
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read the article here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Shahar Taiber & Karen B. Avraham offer this #Perspective on the study by Amariutei et al. (2025) which observes that #MYO7A gene therapy reaches the inner ear ✍️ 💭
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 21, 2025 at 4:04 PM
Shahar Taiber & Karen B. Avraham offer this #Perspective on the study by Amariutei et al. (2025) which observes that #MYO7A gene therapy reaches the inner ear ✍️ 💭
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Ana E. Amariutei of sheffielduni.bsky.social et al. observed that adeno-associated virus-based rescue of #Myo7a expression restores hair-cell function and improves #hearing thresholds in a USH1B mouse strain 🧬 🎶
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 21, 2025 at 2:02 PM
Ana E. Amariutei of sheffielduni.bsky.social et al. observed that adeno-associated virus-based rescue of #Myo7a expression restores hair-cell function and improves #hearing thresholds in a USH1B mouse strain 🧬 🎶
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research: physoc.onlinelibrary.wiley.com/doi/10.1113/...
Daniel Hahn of @ruhr-uni-bochum.de et al. write this #Reply to a recent Letter to the Editor regarding their research into the stretch–shortening cycle✉️ ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 21, 2025 at 12:01 PM
Daniel Hahn of @ruhr-uni-bochum.de et al. write this #Reply to a recent Letter to the Editor regarding their research into the stretch–shortening cycle✉️ ✍️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
This recent #Perspective by Sarah Commodore et al. examines the findings of Mills et al. (2025) that in utero electronic #cigarette exposure may have mind blowing impacts on the offspring ✍️ 💭
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 20, 2025 at 4:01 PM
This recent #Perspective by Sarah Commodore et al. examines the findings of Mills et al. (2025) that in utero electronic #cigarette exposure may have mind blowing impacts on the offspring ✍️ 💭
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
Abul Fajol et al. observed that soft tissue accumulations of phosphate are not always associated with serum phosphate or with calcifications in mouse models of #hyperphosphatemia 💉 🔎
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 20, 2025 at 2:02 PM
Abul Fajol et al. observed that soft tissue accumulations of phosphate are not always associated with serum phosphate or with calcifications in mouse models of #hyperphosphatemia 💉 🔎
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
📜 Read the #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
In this #SymposiumReview, Robyn A. Grant answers 'Can we study #whisker movements to gain insights into the natural #sensory behaviours of mammals?' 🦭 📖
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
November 20, 2025 at 12:01 PM
In this #SymposiumReview, Robyn A. Grant answers 'Can we study #whisker movements to gain insights into the natural #sensory behaviours of mammals?' 🦭 📖
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...
🔗 Read it here: physoc.onlinelibrary.wiley.com/doi/10.1113/...