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Jon Mosser

@jonmosser.com

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Jon Mosser @jonmosser.com · Jun 25

Now out in @thelancet.com: our group's analysis of global vaccination coverage trends, the impact of the COVID pandemic, and progress towards global targets.

Congratulations to all of our co-authors - this was a massive amount of work and comes at a particularly critical time.

Highlights in 🧵

Global, regional, and national trends in routine childhood vaccination coverage from 1980 to 2023 with forecasts to 2030: a systematic analysis for the Global Burden of Disease Study 2023

Our estimates of current vaccine coverage and forecasts to 2030 suggest that achieving IA2030 targets, such as halving zero-dose children compared with 2019 levels and reaching 90% global coverage for...

www.thelancet.com

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Jon Mosser @jonmosser.com · Jun 28

Out now in @plos NTDs - overlap between #LF prevalence and #malaria ITN access / use. Congrats to Joanna Whisnant and the authorship team. This has been a long time coming and great to see it out!

#NTDs #episky #malaria #lymphaticfilariasis

Examining the overlap in lymphatic filariasis prevalence and malaria insecticide-treated net access-use in endemic Africa

Author summary Lymphatic filariasis is a vector-borne disease that can cause significant disability. There is evidence that insecticide-treated nets used by malaria programs can contribute to lymphati...

doi.org

Jon Mosser @jonmosser.com · Jun 25

#pedsky #episky #idsky #pedsidsky

Jon Mosser @jonmosser.com · Jun 25

I had the chance to speak with @npr.org before this announcement, on this critical moment for #vaccination.

"The world is going to have to pick a trajectory," [Mosser] says. "Are we going to turn our backs on one of the most remarkable public health achievements that the world has ever seen?"

The good news (154 million deaths avoided) and bad news about childhood vaccines

A new study points out success stories — and potential obstacles — to bringing vaccines to the world's children.

www.npr.org

Jon Mosser @jonmosser.com · Jun 25

“In the face of demonstration that vaccines are the single most lifesaving technology for children, over half a century, he is asserting a position that the U.S. will not support vaccination. This is utterly disastrous for children around the world and for public health.”

-- @agawande.bsky.social

Kennedy Withdraws U.S. Funding Pledge to International Vaccine Agency

www.nytimes.com

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Jon Mosser @jonmosser.com · Jun 25

Bill Moss of @ivac-hopkins.bsky.social on the challenges to come:

"...the study’s analysis took place prior to the shifts in U.S. federal funding... “The situation is even more challenging, I think, in the coming years than is even outlined in this analysis,” Moss told STAT."

Jon Mosser @jonmosser.com · Jun 25

"Whatever progress we’ve made could be reversed if we don’t maintain and build on our successful #immunization efforts to date.” - Prof. Art Reingold, @berkeleypublichlth.bsky.social.

Read more @statnews.com

STAT @statnews.com · Jun 25

Vaccine hesitancy and misinformation is eroding public confidence in immunization, a new study found
www.statnews.com/2025/06/24/v...

Childhood vaccination coverage was falling across the globe even before Covid

Childhood vaccinations coverage slowed significantly even before the onset of the Covid-19 pandemic, a new study found.

www.statnews.com

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Jon Mosser @jonmosser.com · Jun 25

"Falling global #vaccine coverage, an increase in the numbers of children receiving no vaccines, and delays in vaccination mean that more children will be hospitalised, permanently damaged and die from fully preventable diseases if the trend is not reversed." - Prof. Andrew Pollard

Science Media Centre UK @smclondon.bsky.social · Jun 24

expert reaction to study looking at global childhood vaccination coverage
www.sciencemediacentre.org/expert-react...

Reposted by Jon Mosser

Jon Mosser @jonmosser.com · Jun 25

The evidence couldn't be more clear:

* #Vaccines are safe.
* #Vaccines are effective.
* #Vaccines save lives.

This is the moment for a renewed global commitment to immunization at all levels.

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Jon Mosser @jonmosser.com · Jun 25

We have a choice: do we turn our backs on the most successful public health intervention that the world has ever known? Or do we redouble our efforts to ensure that everyone, everywhere can benefit from the protection of lifesaving #vaccines?

/🧵

Jon Mosser @jonmosser.com · Jun 25

In the decades to come, we need strong global leadership and support from governments and other programs. We need to ensure that national immunization programs have the resources they need to tailor vaccination programs to the needs of their communities.

Jon Mosser @jonmosser.com · Jun 25

The evidence couldn't be more clear:

* #Vaccines are safe.
* #Vaccines are effective.
* #Vaccines save lives.

This is the moment for a renewed global commitment to immunization at all levels.

1 1

Jon Mosser @jonmosser.com · Jun 25

As we move into the second half of this decade, we're at a pivotal moment - coming out of the COVID pandemic, partially but not fully recovered from its impact, and on the heels of more than a decade of slowed progress in many countries. We're at a crossroads.

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Jon Mosser @jonmosser.com · Jun 25

And USAID has had a key role in monitoring vaccine coverage, particularly in LMICs, through the Demographics and Health Surveys. Just over half of all of our survey data sources in this study came from the DHS program. This data is crucial to monitor immunization and many other health metrics.

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Jon Mosser @jonmosser.com · Jun 25

@Gavi has played a major role in supporting many countries in rolling out and scaling up new vaccines and enhancing delivery for more established vaccines, while they work towards more sustainable domestic funding approaches.

Jon Mosser @jonmosser.com · Jun 25

WHO plays a key role in providing guidance, too - for instance, in developing strategies that have been crucial in mitigating the effects of the COVID-19 pandemic on essential health services like immunization.

Jon Mosser @jonmosser.com · Jun 25

In our manuscript, for instance, we rely heavily on data collected by @who.int and @unicef.org, as well as the contextual information that comes from their expertise and close connections with countries.

Jon Mosser @jonmosser.com · Jun 25

In the paper, we point out that the progress made over the past decades has involved deep, sustained collaboration - from local to global levels - and that this needs to continue to achieve the full promise of immunization, as outlined in #IA2030.

Jon Mosser @jonmosser.com · Jun 25

On the eve of Gavi replenishment, this is a particularly critical time, especially in light of announced funding cuts to many key pillars of the global immunization community.

Gates Foundation pledges $1.6 billion to bolster Gavi's childhood vaccine efforts

www.cidrap.umn.edu

Jon Mosser @jonmosser.com · Jun 25

The COVID-19 pandemic then really intensified these challenges. Now, economic uncertainty and shifts in the global immunization funding landscape pose an additional risk, potentially making ambitious targets even harder to achieve.

Jon Mosser @jonmosser.com · Jun 25

Vaccine misinformation and hesitancy continue to play a major role in many settings as well, undermining confidence in safe and effective vaccines.

The State of the World's Children 2023 – The Vaccine Confidence Project

The State of the World’s Children 2023 was developed in collaboration with VCP and using Vaccine Confidence Index data. It reveals that public perception of the importance of vaccines for children dec...

www.vaccineconfidence.org

Jon Mosser @jonmosser.com · Jun 25

There are of course other factors too - Ongoing conflicts, geopolitical instability, and natural disasters have also significantly disrupted vaccination programs.

Jon Mosser @jonmosser.com · Jun 25

In large part, these results reflect deep-seated inequities in vaccination – and longstanding disparities in health system access more broadly. Coverage for many vaccines is consistently lower in LMICs, especially in sub-Saharan Africa and South Asia, where over half of zero-dose children live.

Jon Mosser @jonmosser.com · Jun 25

But, on the other hand, it’s a testament to the power of vaccination that these numbers aren't even higher, and that so many lives have been saved over the first 50 years of #EPI

Global immunization efforts have saved at least 154 million lives over the past 50 years

A major landmark study reveals that global immunization efforts have saved an estimated 154 million lives – or the equivalent of 6 lives every minute of every year – over the past 50 years. The vast m...

www.who.int

Jon Mosser @jonmosser.com · Jun 25

We have vaccines that are safe and effective, and in some cases – like for #measles – we’ve had them for more than 50 years. In 2025, it’s a tragedy that we still have children around the world dying of vaccine preventable diseases.

Jon Mosser @jonmosser.com · Jun 25

Most of the burden of vaccine-preventable diseases, however, takes place in countries with lower immunization coverage. In these countries, low vaccine coverage both reflects and perpetuates longstanding #disparities in health and access to health care.