Josie Maidment
@jmaidment.bsky.social
110 followers 200 following 10 posts
Postdoctoral scientist @ Plant Health Institute of Montpellier (@phimresearch.bsky.social) &‬ Centre de Biologie Structurale. Biochemical/structural studies of proteins to understand plant disease/immunity & improve crop health 🌾🌱 She/her. Views my own.
Posts Media Videos Starter Packs
Reposted by Josie Maidment
Profile of @plantphys.bsky.social EIC Yunde Zhao & RUBY reporter his lab developed; free for use in academic labs & classrooms. “RUBY is making a difference in so many ways because we opened it up to all of science".
"Fundamental research is crucial because it can lead to unexpected discoveries.”
Seeing Red: A UC San Diego Invention is Transforming the Way Scientists Track Genes
UC San Diego biologists have created a transformative new way to monitor genes. The game-changing tool known as RUBY is an inexpensive, easy-to-use technology that allows researchers to visualize gene...
today.ucsd.edu
Deeply saddened by this news. A truly incredible woman who has done so much for so many.

"Find your reasons for hope and let them guide you onward." Jane Goodall, The Book of Hope 🌱

www.bbc.com/news/live/c9...
'An extraordinary legacy': Tributes after chimpanzee expert Jane Goodall dies age 91
The primatologist was a
www.bbc.com
Congrats, great to see it out!
Reposted by Josie Maidment
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators.

www.nature.com/articles/s41...
Reposted by Josie Maidment
An activated wheat CCG10-NLR immune receptor forms an octameric resistosome https://www.biorxiv.org/content/10.1101/2025.08.26.672026v1
Reposted by Josie Maidment
A whole bunch of Assistants Features Editors from @theplantcell.bsky.social and @plantphys.bsky.social getting to know each other 💚
#PlantBio2025
A great group of young scientists.
Reposted by Josie Maidment
And I'll be presenting poster #400-31 tomorrow (Sunday 27 July) from 17:30-19:00 on heavy metal associated-domain containing proteins in rice 🌾
Excited to be in Milwaukee for the @plantphys.bsky.social editorial board meeting and Plant Biology conference #PlantBio25 🌿

Very grateful to the Plant Phys AFE program for this opportunity and looking forward to great discussions over the coming days!
Reposted by Josie Maidment
I am looking for a (bio)chemist to join the lab and help us making affinity-based probes for proteases! The project is truly interdisciplinary with a strong computational chemistry component, peptide synthesis and plant biochemistry!
Text me if interested and please spread the word!
📣We offer a #PhDposition @dfg.de-funded #RTG2670 BEAM: "Beyond Amphiphilicity - Self-Organization of Soft Matter via Multiple Noncovalent Interactions" with @marischuster.bsky.social.

🔗More: www.ipb-halle.de/en/career/jo...

📅Apply now!

#MolecularModelling #Proteases #SciJobs #PhDjobs
Reposted by Josie Maidment
🎉 Exciting news during #2025ISMPMI
Our AlphaFold sensor vs helper NLR paper is now published in @newphyt.bsky.social‬!

Big thanks to the reviewers for their constructive feedback 🙏

📖 Check out the peer-reviewed version here 👇
🔗 nph.onlinelibrary.wiley.com/doi/10.1111/...

bsky.app/profile/yusu...
After great talks at #2025ISMPMI on de novo design of pathogen protein binders for receptor engineering - perfect timing for this preprint from colleagues at the Centre de Biologie Structurale!
You designed binders for your favourite protein and wish there was a way to experimentally screen them within 24h w/ only a set of pipettes and a plate reader?

Check out our Cell-Free 2-Hybrid approach (CF2H)

Full post: tinyurl.com/48cz5nb6

Preprint: www.biorxiv.org/cgi/content/...
Reposted by Josie Maidment
#2025ISMPMI 📣 In silico screening of PRR-epitope interactions is now possible!

Here, we developed mamp-ml to predict their immunogenic outcomes without structural context. Let's accelerate engineering plant receptors for robust resistance! 🚀🌱 Small 🧵

www.biorxiv.org/content/10.1...
mamp-ml: A deep learning approach to epitope immunogenicity in plants
Eukaryotes detect biomolecules through surface-localized receptors, key signaling components. A subset of receptors survey for pathogens, induce immunity, and restrict pathogen growth. Comparative gen...
www.biorxiv.org
If you're at #2025ISMPMI, please come talk to me if you have comments/questions/feedback!

I'll be presenting some of this work in the poster session on Thursday (P-212) and in the concurrent session "Structure Informed Synthetic Biology: From Design to Function" on Thursday afternoon.
I'm massively grateful to all co-authors, but especially to co-first author Svenja Saile, who is both an incredibly rigorous and conscientious scientist and a wonderful colleague 🌱
Very happy to share our preprint on heavy metal associated (HMA) domain-containing rice proteins bound by the rice blast MAX effector AVR-Pia! 🌾
The Magnaporthe oryzae MAX effector AVR-Pia binds a novel group of rice HMA domain-containing proteins https://www.biorxiv.org/content/10.1101/2025.07.11.664054v1
Such a great evening with past and present members of the CIME team! #2025ISMPMI @phimresearch.bsky.social
Reposted by Josie Maidment
Connections are in action in Cologne! At #2025ISMPMI, the poster sessions aren’t just about groundbreaking research—they’re about meeting peers, collaboration, and sharing ideas that move plant-microbe science forward.

Full poster hours here: bit.ly/44LqCvc

#plantscience #networking
Looking forward to the start of #2025ISMPMI today!

If you're interested in structural studies of effector/host target complexes, come talk to me!

🗣️ Talk: Thurs 17th 16:25 Concurrent session "Structure Informed Synthetic Biology: From Design To Function"

📄 Poster: P-212, Thurs 17th 13:30-15:15

🌱🦠