A systematic literature review and bayesian meta-analysis of oral vancomycin primary prophylaxis for Clostridioides difficile infection in stem cell transplant patients - Volume 5 Issue 1

How to leverage medication use evaluations for antimicrobial stewardship goals: a primer for physicians - Volume 5 Issue 1

National Healthcare Safety Network… we need to talk… - Volume 5 Issue 1

Unraveling indications for discharge antibiotics: the Devil’s in the details - Volume 5 Issue 1

npj Antimicrobials and Resistance - Towards the integration of antibiotic resistance gene mobility into environmental surveillance and risk assessment

The bacilli that shaped Andean medicine, haunted the trenches of war, and still hides in our cats.

Effectiveness and acceptability of ventilation modifications in healthcare facilities, Liberia 2022–2023 - Volume 5 Issue 1

Effectiveness and acceptability of ventilation modifications in healthcare facilities, Liberia 2022–2023 - Volume 5 Issue 1

Effectiveness and acceptability of ventilation modifications in healthcare facilities, Liberia 2022–2023 - Volume 5 Issue 1

Low diagnostic yield of repeat urine cultures in hospitalized patients at a tertiary center in Northern California, 2023–2024

Hospital treatment for children with severe malnutrition may facilitate antibiotic resistance. Here, using rectal swabs from 1,371 children receiving treatment for severe acute malnutrition in Niger, ...

Beyond the basics: rethinking antimicrobial stewardship by targeting cytomegalovirus immune globulin for immunocompromised patients - Volume 5 Issue 1

AbstractVentriculoperitoneal (VP) shunts are the mainstay for cerebrospinal fluid (CSF) diversion in patients with refractory coccidioidal meningitis (CM)-associated hydrocephalus. Abdominal pseudocysts (APCs), an uncommon but known complication of distal shunt catheters, have not been well described in CM. We conducted a retrospective study of 124 patients with CM who underwent VP shunt placement between 2010 and 2024. APCs occurred in 21 patients (17%), with most presenting with symptoms of shunt malfunction rather than abdominal complaints. This incidence is notably higher than previously reported in patients with hydrocephalus due to other etiologies. Evidence of active Coccidioides infection was present in 71% of patients. Imaging typically revealed fluid collections at the distal catheter tip, and most patients underwent surgical intervention targeting the distal shunt. Despite intervention, recurrent shunt failures occurred in a substantial proportion. These findings add to the limited literature on APCs in CM and may inform future research into their presentation, contributing factors, and management.

Striking a balance: strategies for addressing single-use surgical equipment in infection prevention - Volume 5 Issue 1