Aguirre-Ghiso Lab
@jaguirreghisolab.bsky.social
We study how micro-environmental and epigenetic mechanisms drive cancer cells into dormancy. We seek to control this biology to prevent and treat metastasis. https://einsteinmed.edu/faculty/16974/julio-aguirre-ghiso
Pinned
Honored to receive the 2026 Paget-Ewing Award, the highest honor from @metastasisresearch.bsky.social. Humbled for sharing this recognition with past awardees, all giants of metastasis research. Grateful for this acknowledgment of cancer dormancy research and for all my amazing colleagues at MRS!
Wonderful end of year celebration and secret Santa at the @jaguirreghisolab.bsky.social lab! Thanks all for a wonderful year!
December 6, 2025 at 8:45 PM
Wonderful end of year celebration and secret Santa at the @jaguirreghisolab.bsky.social lab! Thanks all for a wonderful year!
Fascinating !
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Eight millennia of continuity of a previously unknown lineage in Argentina - Nature
A previously unsampled deep lineage in central Argentina was discovered that had distinctive genetic drift by 8,500 bp and persisted as the main Native American ancestry component in the reg...
www.nature.com
November 27, 2025 at 1:01 AM
Fascinating !
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Aguirre-Ghiso Lab
My mum says “you never get over not knowing where your next meal is coming from” 🙁
November 23, 2025 at 10:19 PM
My mum says “you never get over not knowing where your next meal is coming from” 🙁
Reposted by Aguirre-Ghiso Lab
📢 SIGN & SHARE THE PETITION! 📢
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
Sign the Petition
Support a New York State Biomedical Institute for a Healthier, More Affordable Future
c.org
November 24, 2025 at 3:53 PM
📢 SIGN & SHARE THE PETITION! 📢
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW
Reposted by Aguirre-Ghiso Lab
EBRI will power the full pipeline — from foundational discovery to drug development — and support education, technology & clinical trials.
Momentum matters. Broad public support will help make this real.
We all have a hinterland — time to gather your troops!
✍️ Please sign and tell 10 to tell 10…
Momentum matters. Broad public support will help make this real.
We all have a hinterland — time to gather your troops!
✍️ Please sign and tell 10 to tell 10…
November 24, 2025 at 3:57 PM
EBRI will power the full pipeline — from foundational discovery to drug development — and support education, technology & clinical trials.
Momentum matters. Broad public support will help make this real.
We all have a hinterland — time to gather your troops!
✍️ Please sign and tell 10 to tell 10…
Momentum matters. Broad public support will help make this real.
We all have a hinterland — time to gather your troops!
✍️ Please sign and tell 10 to tell 10…
What a pleasure to have hosted Dr. Joan Massague from MSKCC @mskcancercenter.bsky.social who visited us all day and delivered an exceptional lecture for our @einsteinmededu.bsky.social Montefiore Einstein Comprehensive Cancer Center distinguished lecture series. Thanks for visiting!
November 14, 2025 at 12:42 AM
What a pleasure to have hosted Dr. Joan Massague from MSKCC @mskcancercenter.bsky.social who visited us all day and delivered an exceptional lecture for our @einsteinmededu.bsky.social Montefiore Einstein Comprehensive Cancer Center distinguished lecture series. Thanks for visiting!
We wrapped the @cdi-einstein.bsky.social Retreat with four impressive projects from our workshop by Unai Heras Manterola, Lindsay Lafave, Maria Sosa, and Kamini Singh—covered dormancy & bioengineering, neoantigens, transcriptional heterogeneity & lung cancer. Wow! Thanks to all who participated!
November 7, 2025 at 6:43 PM
We wrapped the @cdi-einstein.bsky.social Retreat with four impressive projects from our workshop by Unai Heras Manterola, Lindsay Lafave, Maria Sosa, and Kamini Singh—covered dormancy & bioengineering, neoantigens, transcriptional heterogeneity & lung cancer. Wow! Thanks to all who participated!
Exciting to wrap up the presentations at our CDI retreat with two phenomenal talks by @cdi-einstein.bsky.social latest recruits who will start in 2026 @swagatag.bsky.social from @mit.edu and @samhegde.bsky.social from @mountsinainyc.bsky.social welcome to @einsteinmededu.bsky.social
November 7, 2025 at 3:20 PM
Exciting to wrap up the presentations at our CDI retreat with two phenomenal talks by @cdi-einstein.bsky.social latest recruits who will start in 2026 @swagatag.bsky.social from @mit.edu and @samhegde.bsky.social from @mountsinainyc.bsky.social welcome to @einsteinmededu.bsky.social
Today we had a phenomenal first day of our @cdi-einstein.bsky.social retreat. Great talks by @soledadsosalab.bsky.social Anna Skwarska and John McAuliffe.
November 7, 2025 at 1:08 AM
Today we had a phenomenal first day of our @cdi-einstein.bsky.social retreat. Great talks by @soledadsosalab.bsky.social Anna Skwarska and John McAuliffe.
Now the Keynote Lecture at our @cdi-einstein.bsky.social retreat delivered by @amulyasreekumar.bsky.social from the Chodosh team at University of Pennsylvania - great work!
November 6, 2025 at 2:13 PM
Now the Keynote Lecture at our @cdi-einstein.bsky.social retreat delivered by @amulyasreekumar.bsky.social from the Chodosh team at University of Pennsylvania - great work!
Getting ready to start our @cdi-einstein.bsky.social Retreat!
November 6, 2025 at 12:57 PM
Getting ready to start our @cdi-einstein.bsky.social Retreat!
I wonder if such strategy might limit early dissemination...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Anti-progestin therapy targets hallmarks of breast cancer risk - Nature
Results of an early-phase breast cancer prevention trial demonstrate the potential for breast cancer prevention in premenopausal women with anti-progestin therapy by inducing epithelial–stromal remode...
www.nature.com
November 5, 2025 at 6:30 PM
I wonder if such strategy might limit early dissemination...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The @cdi-einstein.bsky.social retreat is tomorrow! Featuring 1.5 days of exciting science with keynote by Dr. Lewis Chodosh (UPenn) and talks from our faculty and students. Thanks to MECCC, SWCRF, and Pershing Square Philanthropies for their support!
November 5, 2025 at 1:54 PM
The @cdi-einstein.bsky.social retreat is tomorrow! Featuring 1.5 days of exciting science with keynote by Dr. Lewis Chodosh (UPenn) and talks from our faculty and students. Thanks to MECCC, SWCRF, and Pershing Square Philanthropies for their support!
Honored to receive the 2026 Paget-Ewing Award, the highest honor from @metastasisresearch.bsky.social. Humbled for sharing this recognition with past awardees, all giants of metastasis research. Grateful for this acknowledgment of cancer dormancy research and for all my amazing colleagues at MRS!
October 31, 2025 at 12:29 AM
Honored to receive the 2026 Paget-Ewing Award, the highest honor from @metastasisresearch.bsky.social. Humbled for sharing this recognition with past awardees, all giants of metastasis research. Grateful for this acknowledgment of cancer dormancy research and for all my amazing colleagues at MRS!
Yesterday I gave a keynote at the Invasive Lobular Breast Cancer Think Tank at MSKCC (organized by S. Oesterreich, F. Pareja Zea, C Desmedt & R Jankowitz) thanks 4 the invite. Then joined the NCI MetNet meeting @rockefeller.edu (thx 2 Sohail Tavazoie & NCI team). Our U01 trainees did an amazing job!
October 29, 2025 at 8:27 PM
Yesterday I gave a keynote at the Invasive Lobular Breast Cancer Think Tank at MSKCC (organized by S. Oesterreich, F. Pareja Zea, C Desmedt & R Jankowitz) thanks 4 the invite. Then joined the NCI MetNet meeting @rockefeller.edu (thx 2 Sohail Tavazoie & NCI team). Our U01 trainees did an amazing job!
Life Lessons from (Very Old) Bowhead Whales www.nytimes.com/2025/10/29/s...
Life Lessons from (Very Old) Bowhead Whales
www.nytimes.com
October 29, 2025 at 8:08 PM
Life Lessons from (Very Old) Bowhead Whales www.nytimes.com/2025/10/29/s...
Great to see an Educational Session on Dormancy and Reactivation of Breast Cancer Cells at Distant Metastatic Sites at the @sabcs.bsky.social meeting this year. sabcs.org/events/
Events - San Antonio Breast Cancer Symposium
sabcs.org
October 21, 2025 at 2:06 PM
Great to see an Educational Session on Dormancy and Reactivation of Breast Cancer Cells at Distant Metastatic Sites at the @sabcs.bsky.social meeting this year. sabcs.org/events/
This morning - early - I had the pleasure of presenting to the faculty and trainees of the Department of Pathology and Oncology Juntendo University School of Medicine in Tokyo. Thanks for a great Q&A and to Drs. Mezawa and Orimo for the invitation.
October 21, 2025 at 11:27 AM
This morning - early - I had the pleasure of presenting to the faculty and trainees of the Department of Pathology and Oncology Juntendo University School of Medicine in Tokyo. Thanks for a great Q&A and to Drs. Mezawa and Orimo for the invitation.
Yesterday I had the privilege of participating in a brainstorming session with the leadership of the NR2F1 Foundation to determine if our NR2F1 agonists may be of use to help individuals with the various mutations in this gene. Congratulations for the work you’re doing.
October 18, 2025 at 3:51 PM
Yesterday I had the privilege of participating in a brainstorming session with the leadership of the NR2F1 Foundation to determine if our NR2F1 agonists may be of use to help individuals with the various mutations in this gene. Congratulations for the work you’re doing.
Today we honor three giants of @einsteincellbio.bsky.social that developed their careers @einsteinmededu.bsky.social Their work has positively impacted not only science but millions of humans across the world. Congrats to Margaret Kielian, Pamela Stanley & Matthew Scharff and thank you!
October 16, 2025 at 5:29 PM
Today we honor three giants of @einsteincellbio.bsky.social that developed their careers @einsteinmededu.bsky.social Their work has positively impacted not only science but millions of humans across the world. Congrats to Margaret Kielian, Pamela Stanley & Matthew Scharff and thank you!
Congratulations to Lucia Petriz Otaño PhD student in the JAG Lab for earning the Master of Science degree in Biomedical Sciences after passing the qualifying exam! Lucia is
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
October 13, 2025 at 5:23 PM
Congratulations to Lucia Petriz Otaño PhD student in the JAG Lab for earning the Master of Science degree in Biomedical Sciences after passing the qualifying exam! Lucia is
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy
working on how macrophages, viral infections & downstream transcriptional mechanisms control the awakening from dormancy