A pH-driven DNA nanomachine based on the human α-thrombin binding aptamer was designed for the specific catch-and-release of human α-thrombin at neutral and acidic pH, respectively. In neutral conditi...

Utilizing ultrasound as an external stimulus to remotely modulate the activity of proteins is an important aspect of sonopharmacology and establishes the basis for the emerging field of sonogenetics. ...

Metal–organic frameworks have demonstrated great potential as drug delivery systems, but the biocompatibility of the MOF components is often overlooked. Here, a vitamin C and zinc-based MOF with permanent microporosity is designed, and successful loading and release of model drug urea from the MOF pores, as well as degradation of the framework, are demonstrated.

In this Review, White and Sears examine recent evidence showing the link between the gut microbiota and colorectal cancer (CRC) and discuss the roles and mechanisms of specific microorganisms as well as of complex microbial communities in the pathogenesis of CRC.

Plum pox virus is a member of the genus Potyvirus in the family Potyviridae. The significance of this virus is underscored by its large strain diversity, wide host range, broad geographical distribut...