Vasanthi Jayaraman
@frettinglab.bsky.social
Professor, University of Texas Health Science Center at Houston
Membrane protein dynamics and function, Fluorescence, Spectroscopy and Electrophysiology
Editor in Chief Biophysical Journal
Membrane protein dynamics and function, Fluorescence, Spectroscopy and Electrophysiology
Editor in Chief Biophysical Journal
Reposted by Vasanthi Jayaraman
Our new PNAS paper "Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease" is out: www.pnas.org/doi/10.1073/... 1/3
Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease | PNAS
Sickle cell disease (SCD), an inherited blood disorder caused by a mutation in the
β-globin gene, is characterized by sickle erythrocytes that are ...
www.pnas.org
October 3, 2025 at 4:53 PM
Our new PNAS paper "Enhanced PIEZO1 function contributes to the pathogenesis of sickle cell disease" is out: www.pnas.org/doi/10.1073/... 1/3
Reposted by Vasanthi Jayaraman
My alma mater is hiring a microbiologist! Assistant/Associate Prof. 👇👇
Assistant/Associate Professor, Microbiology and Molecular Genetics - McGovern Medical School in Texas, United States | Faculty & Physicians at UTHealth Houston
Apply for Assistant/Associate Professor, Microbiology and Molecular Genetics - McGovern Medical School job with UTHealth Houston in Texas, United States. Faculty & Physicians at UTHealth Houston
careers.uth.tmc.edu
August 17, 2025 at 11:54 AM
My alma mater is hiring a microbiologist! Assistant/Associate Prof. 👇👇
While not front page, I was happy to see this article in NYtimes about importance of fundamental research. www.nytimes.com/2025/05/16/s...
9 Federally Funded Scientific Breakthroughs That Changed Everything
www.nytimes.com
May 16, 2025 at 12:16 PM
While not front page, I was happy to see this article in NYtimes about importance of fundamental research. www.nytimes.com/2025/05/16/s...
Reposted by Vasanthi Jayaraman
Over 90% of Americans rely on federally funded science, But only 10% are worried about losing access to it.
That’s a dangerous disconnect.
Help us close the gap. Join our #SummerFightForScience and help spread the word about how essential science is to everyday lives.
www.npr.org/2025/05/06/n...
That’s a dangerous disconnect.
Help us close the gap. Join our #SummerFightForScience and help spread the word about how essential science is to everyday lives.
www.npr.org/2025/05/06/n...
Most Americans use federal science information on a weekly basis, a new poll finds
Most Americans frequently use federal science information. But few are concerned that cuts to federal science spending could affect their access to such information, a new poll finds.
www.npr.org
May 15, 2025 at 4:54 PM
Over 90% of Americans rely on federally funded science, But only 10% are worried about losing access to it.
That’s a dangerous disconnect.
Help us close the gap. Join our #SummerFightForScience and help spread the word about how essential science is to everyday lives.
www.npr.org/2025/05/06/n...
That’s a dangerous disconnect.
Help us close the gap. Join our #SummerFightForScience and help spread the word about how essential science is to everyday lives.
www.npr.org/2025/05/06/n...
Congratulations @ulises-glz.bsky.social!! Thanks for making me a part of your graduate journey!!
May 14, 2025 at 12:25 AM
Congratulations @ulises-glz.bsky.social!! Thanks for making me a part of your graduate journey!!
Congratulations!! That’s wonderful news!!
May 10, 2025 at 12:04 PM
Congratulations!! That’s wonderful news!!
thank you for editing this. It is going to be a fantastic issue!
May 7, 2025 at 4:29 PM
thank you for editing this. It is going to be a fantastic issue!
The Spencer Foundation is offering bridge funding for those who lost NSF research grants.
The Spencer Foundation is offering rapid response bridge funding for those who lost NSF research grants.
www.spencer.org/grant_types/...
www.spencer.org/grant_types/...
Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
www.spencer.org
May 3, 2025 at 1:09 PM
The Spencer Foundation is offering bridge funding for those who lost NSF research grants.
Reposted by Vasanthi Jayaraman
Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...
Cell membranes sustain phospholipid imbalance via cholesterol asymmetry
This work challenges a major assumption in cell biology by showing that lipid bilayers
can have drastically different phospholipid abundances between their two leaflets.
This lipid abundance asymmetry...
www.cell.com
April 3, 2025 at 3:07 PM
Groundbreaking study in Cell from @leventallab.bsky.social: phospholipid asymmetry is a defining feature of the plasma membrane and cholesterol fills the holes — major implications for how this membrane works. A #lipidtime must-read! www.cell.com/cell/abstrac...
Reposted by Vasanthi Jayaraman
Here's our newest study: we reveal the molecular principles of neuronal excitation by glutamate, and how physiological temperatures influence this process.
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com
March 26, 2025 at 4:29 PM
Here's our newest study: we reveal the molecular principles of neuronal excitation by glutamate, and how physiological temperatures influence this process.
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com
www.nature.com/articles/s41...
www.nature.com/articles/d41...
Led by @anish-mondal07.bsky.social, published in @natureportfolio.nature.com
Reposted by Vasanthi Jayaraman
Congratulations, Eric and Vasanthi, for well-deserved recognition at #BPS2025!
And many thanks to Sudha and Chris (not shown) for the best of biophysics in LA.
And many thanks to Sudha and Chris (not shown) for the best of biophysics in LA.
February 18, 2025 at 7:05 AM
Congratulations, Eric and Vasanthi, for well-deserved recognition at #BPS2025!
And many thanks to Sudha and Chris (not shown) for the best of biophysics in LA.
And many thanks to Sudha and Chris (not shown) for the best of biophysics in LA.
Reposted by Vasanthi Jayaraman
See below the whole stellar panel!
Did you submit a paper to BJ this year?
There is still a chance that you may be in the lineup at #BPS2025 in SF!
Did you submit a paper to BJ this year?
There is still a chance that you may be in the lineup at #BPS2025 in SF!
February 18, 2025 at 7:05 PM
See below the whole stellar panel!
Did you submit a paper to BJ this year?
There is still a chance that you may be in the lineup at #BPS2025 in SF!
Did you submit a paper to BJ this year?
There is still a chance that you may be in the lineup at #BPS2025 in SF!
Reposted by Vasanthi Jayaraman
Nice paper. I recommend to check the review file for a lot of extra interesting details. Still a lot to understand about TARP action, despite >20 years of work from many groups.
#iglurs #biophysics #receptors
#iglurs #biophysics #receptors
We took a precise look at how claudin-like tetraspanins (TARPs) regulate AMPA receptors. #CryoEM helped us identify motifs that are critical for receptor regulation, and point to how TARPs evolved from claudins to a regulatory role in the CNS vs. tissue barriers like claudins! rdcu.be/d6DOu
January 18, 2025 at 2:03 PM
Nice paper. I recommend to check the review file for a lot of extra interesting details. Still a lot to understand about TARP action, despite >20 years of work from many groups.
#iglurs #biophysics #receptors
#iglurs #biophysics #receptors
Sad to hear about the passing of Prof. Mike Sheetz. He was a pioneer and leader in Mechanobiology.
Deeply saddened by the passing of Prof. Mike Sheetz, a true leader in Mechanobiology. His groundbreaking work on Kinesin, membrane organization, and mechanotransduction has left an indelible mark. A tremendous loss to science. #Mechanobiology #Science #LaskerAward
February 1, 2025 at 10:30 PM
Sad to hear about the passing of Prof. Mike Sheetz. He was a pioneer and leader in Mechanobiology.
Reposted by Vasanthi Jayaraman
One main pain point: interdisciplinary work is often judged by the highest standards in *both* disciplines. This creates an almost impossible burden, effectively extinguishing creative work. Sure, some standards are there for a reason, but more often than not, they are just stock critiques.
💯. Most aspects of the system subtly (or not-so-subtly) push you back in your lane, making interdisciplinary work very hard.
Expert's Dilemma: the more specialized you become, the less open you are to creative solutions from other fields. But the more you explore other fields, the more you risk losing credibility in your home field.
Interdisciplinary work is still not really embraced by academia.
Interdisciplinary work is still not really embraced by academia.
January 5, 2025 at 5:00 PM
One main pain point: interdisciplinary work is often judged by the highest standards in *both* disciplines. This creates an almost impossible burden, effectively extinguishing creative work. Sure, some standards are there for a reason, but more often than not, they are just stock critiques.
Good read discussing scientific publishing trends. I liked the discussion on turn around times and impact inflation of different journals.
The strain on scientific publishing: we set out to characterise the remarkable growth of the scientific literature in the last few years, in spite of declining growth in total scientists. What is going on?
direct.mit.edu/qss/article/...
A 🧵 1/n
#AcademicSky #PhDchat #ScientificPublishing #SciPub
direct.mit.edu/qss/article/...
A 🧵 1/n
#AcademicSky #PhDchat #ScientificPublishing #SciPub
January 5, 2025 at 7:02 PM
Good read discussing scientific publishing trends. I liked the discussion on turn around times and impact inflation of different journals.
Visiting Sastra and talking with the students was definitely one of the highlights of my 2024!! Happy New year.
December 25, 2024 at 12:35 AM
Visiting Sastra and talking with the students was definitely one of the highlights of my 2024!! Happy New year.
Reposted by Vasanthi Jayaraman
As the chair of the Intrinsically Disordered Proteins Subgroup of @biophysicalsoc.bsky.social I'm happy to announce the exciting scientific program put together by program co-chairs Dorothee Dormann & Lukasz Joachimiak.
Looking forward to seeing you in Los Angeles!
www.biophysics.org/2025meeting/...
Looking forward to seeing you in Los Angeles!
www.biophysics.org/2025meeting/...
December 5, 2024 at 6:54 AM
As the chair of the Intrinsically Disordered Proteins Subgroup of @biophysicalsoc.bsky.social I'm happy to announce the exciting scientific program put together by program co-chairs Dorothee Dormann & Lukasz Joachimiak.
Looking forward to seeing you in Los Angeles!
www.biophysics.org/2025meeting/...
Looking forward to seeing you in Los Angeles!
www.biophysics.org/2025meeting/...
Welcome Erdinc!
December 3, 2024 at 1:16 PM
Welcome Erdinc!
Reposted by Vasanthi Jayaraman
Re-reading your rejected manuscript
November 30, 2024 at 2:26 PM
Re-reading your rejected manuscript
Reposted by Vasanthi Jayaraman
Nominate a colleague - or yourself - to speak in the "New and Notable Symposium" at #BPS2025 Annual Meeting in LA.
Hurry, Deadline is Dec 2:
www.surveymonkey.com/r/HPMRT6H
Hurry, Deadline is Dec 2:
www.surveymonkey.com/r/HPMRT6H
Suggestions for the BPS 2025 Annual Meeting "New and Notable" Symposium
Take this survey powered by surveymonkey.com. Create your own surveys for free.
www.surveymonkey.com
November 26, 2024 at 11:14 PM
Nominate a colleague - or yourself - to speak in the "New and Notable Symposium" at #BPS2025 Annual Meeting in LA.
Hurry, Deadline is Dec 2:
www.surveymonkey.com/r/HPMRT6H
Hurry, Deadline is Dec 2:
www.surveymonkey.com/r/HPMRT6H
When I was a new PI my grant was triaged for proposing to do FRET and a few months later a review was published by a study section member who said the future was FRET measurements in these channels 😂
November 27, 2024 at 1:48 PM
When I was a new PI my grant was triaged for proposing to do FRET and a few months later a review was published by a study section member who said the future was FRET measurements in these channels 😂
As PI’s we never receive training on how to manage people. I still struggle with this aspect of running a lab. This is good read and reminder on how to build a supportive environment.
There's lots of exciting things going on! Our very own Haoming You wrote this piece in Scientifica about how to build a supportive research culture in the lab 👇
www.scientifica.uk.com/neurowire/bu...
www.scientifica.uk.com/neurowire/bu...
Blog: Building a Supportive Research Environment in the Lab
Haoming You, PhD student at the Grubb Lab, CDN, KCL provides an insight into how to create a supportive research environment in the lab
www.scientifica.uk.com
November 26, 2024 at 1:16 PM
As PI’s we never receive training on how to manage people. I still struggle with this aspect of running a lab. This is good read and reminder on how to build a supportive environment.
Reposted by Vasanthi Jayaraman
I want to credit @popstarlab.bsky.social for the great idea to make this feed! Thx Gabriela.
Paging @frettinglab.bsky.social @ecekuru.bsky.social @wdhale.bsky.social and all other #iGluRs fans...
Paging @frettinglab.bsky.social @ecekuru.bsky.social @wdhale.bsky.social and all other #iGluRs fans...
I made a feed for glutamate receptor ion channels.
It picks up anything with the tag #iGluRs and also AMPA and NMDA receptors. (Sorry KAR and delta fans, only three terms, forgive me)
You can pin the feed and/or like it.
bsky.app/profile/did:...
It picks up anything with the tag #iGluRs and also AMPA and NMDA receptors. (Sorry KAR and delta fans, only three terms, forgive me)
You can pin the feed and/or like it.
bsky.app/profile/did:...
November 24, 2024 at 9:17 AM
I want to credit @popstarlab.bsky.social for the great idea to make this feed! Thx Gabriela.
Paging @frettinglab.bsky.social @ecekuru.bsky.social @wdhale.bsky.social and all other #iGluRs fans...
Paging @frettinglab.bsky.social @ecekuru.bsky.social @wdhale.bsky.social and all other #iGluRs fans...