FOR5159
@for5159.bsky.social
We're a group of enthusiastic scientists aiming to uncover the dynamic principles of prefrontal processing underlying cognitive flexibility!
Reposted by FOR5159
This review has turned into my go-to paper for rodent PFC circuit. Useful in the lab and for teaching. Thanks @panastasiades.bsky.social and @carterlab.bsky.social for writing this. www.cell.com/trends/neuro...
Circuit organization of the rodent medial prefrontal cortex
The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted
in many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous
variety of projection neurons a...
www.cell.com
February 18, 2025 at 9:21 AM
This review has turned into my go-to paper for rodent PFC circuit. Useful in the lab and for teaching. Thanks @panastasiades.bsky.social and @carterlab.bsky.social for writing this. www.cell.com/trends/neuro...
Literature highlight, this week from our consortium! Muyers et al. used an olfaction-guided spatial memory task in mice to show that prefrontal neurons encode both generalized and trajectory-specific aspects of task structure.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Conjoint generalized and trajectory-specific coding of task structure by prefrontal neurons
Neurons in the medial prefrontal cortex (mPFC) show spatially modulated activities.
Muysers et al. show that mPFC neurons fall into distinct functional classes that differ
in terms of their spatial tu...
www.cell.com
March 15, 2025 at 9:14 AM
Literature highlight, this week from our consortium! Muyers et al. used an olfaction-guided spatial memory task in mice to show that prefrontal neurons encode both generalized and trajectory-specific aspects of task structure.
www.cell.com/cell-reports...
www.cell.com/cell-reports...
Literature highlight of the week: Elston and Wallis used a state-dependent choice task in monkeys to show that the hippocampus relays context-based information via theta waves to the orbitofrontal cortex, which informs valuation and...
January 14, 2025 at 3:27 PM
Literature highlight of the week: Elston and Wallis used a state-dependent choice task in monkeys to show that the hippocampus relays context-based information via theta waves to the orbitofrontal cortex, which informs valuation and...
Literature Highlight of the Week:
Almoril-Porras and Calvo et al. demonstrate the necessity of gap junctions in the temperature gradient migration strategies of C....
Almoril-Porras and Calvo et al. demonstrate the necessity of gap junctions in the temperature gradient migration strategies of C....
January 14, 2025 at 3:27 PM
Literature Highlight of the Week:
Almoril-Porras and Calvo et al. demonstrate the necessity of gap junctions in the temperature gradient migration strategies of C....
Almoril-Porras and Calvo et al. demonstrate the necessity of gap junctions in the temperature gradient migration strategies of C....
Mugan et al. investigate the effects of environmental complexity on ensemble firing and local field potential in the dmPFC, hippocampus, and dlstriatum of freely moving rats during a foraging task.
https://www.sciencedirect.com/science/article/pii/S0896627324006986?via%3Dihub#bib26
https://www.sciencedirect.com/science/article/pii/S0896627324006986?via%3Dihub#bib26
ScienceDirect
www.sciencedirect.com
January 14, 2025 at 3:27 PM
Mugan et al. investigate the effects of environmental complexity on ensemble firing and local field potential in the dmPFC, hippocampus, and dlstriatum of freely moving rats during a foraging task.
https://www.sciencedirect.com/science/article/pii/S0896627324006986?via%3Dihub#bib26
https://www.sciencedirect.com/science/article/pii/S0896627324006986?via%3Dihub#bib26
Qian et al. explore the dynamic interplay between relevant information and distractor representations in the lateral prefrontal cortex (LPFC) and prearcuate cortex (PAC) of macaque monkeys.
https://www.jneurosci.org/content/early/2024/12/08/JNEUROSCI.1770-24.2024.long
https://www.jneurosci.org/content/early/2024/12/08/JNEUROSCI.1770-24.2024.long
January 14, 2025 at 3:27 PM
Qian et al. explore the dynamic interplay between relevant information and distractor representations in the lateral prefrontal cortex (LPFC) and prearcuate cortex (PAC) of macaque monkeys.
https://www.jneurosci.org/content/early/2024/12/08/JNEUROSCI.1770-24.2024.long
https://www.jneurosci.org/content/early/2024/12/08/JNEUROSCI.1770-24.2024.long
Literature highlight of the week: Chen et al. explore thalamic representation and thalamocortical interactions that contribute to hierarchical cognitive control in humans
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002937
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002937
The thalamus encodes and updates context representations ...
The cortico-striatal-thalamic circuit is involved in upda...
journals.plos.org
January 14, 2025 at 3:28 PM
Literature highlight of the week: Chen et al. explore thalamic representation and thalamocortical interactions that contribute to hierarchical cognitive control in humans
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002937
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002937
Literature highlight of the week: Xu et al. show how robustness and sensitivity coexist in neural networks by analyzing neural dynamics in the monkey prefrontal cortex and using comptational approaches
https://www.pnas.org/doi/epub/10.1073/pnas.240948712
https://www.pnas.org/doi/epub/10.1073/pnas.240948712
January 14, 2025 at 3:28 PM
Literature highlight of the week: Xu et al. show how robustness and sensitivity coexist in neural networks by analyzing neural dynamics in the monkey prefrontal cortex and using comptational approaches
https://www.pnas.org/doi/epub/10.1073/pnas.240948712
https://www.pnas.org/doi/epub/10.1073/pnas.240948712
Literature highlight of the week: Van de Maele et al. propose a hierarchical active inference model clarifying how the hippocampal-medial prefrontal cortex circuit solves spatial interaction tasks by bridging physical and task-space maps....
January 14, 2025 at 3:28 PM
Literature highlight of the week: Van de Maele et al. propose a hierarchical active inference model clarifying how the hippocampal-medial prefrontal cortex circuit solves spatial interaction tasks by bridging physical and task-space maps....
Literature highlight of the week: Lam et al. used a decision task with rule reversals in tree shrews and found that relevant thalamic neurons drive prefrontal reconfiguration following a reversal by attributing errors to an environmental...
January 14, 2025 at 3:28 PM
Literature highlight of the week: Lam et al. used a decision task with rule reversals in tree shrews and found that relevant thalamic neurons drive prefrontal reconfiguration following a reversal by attributing errors to an environmental...
Literature highlight of the week: El-Gaby et al. identify an algorithm that relates medial frontal cortex role in schema formation and sequence memory, by internally organizing mnemonic activity according to an abstract structure shared by different...
January 14, 2025 at 3:28 PM
Literature highlight of the week: El-Gaby et al. identify an algorithm that relates medial frontal cortex role in schema formation and sequence memory, by internally organizing mnemonic activity according to an abstract structure shared by different...
Literature highlight of the week: Mugan et al. show that complex naturalistic environments modulate decision-making strategies, neural representations, and interactions among the hippocampus, dorsolateral striatum, and dorsomedial prefrontal...
January 14, 2025 at 3:28 PM
Literature highlight of the week: Mugan et al. show that complex naturalistic environments modulate decision-making strategies, neural representations, and interactions among the hippocampus, dorsolateral striatum, and dorsomedial prefrontal...
Literature highlight of the week: Hansen et al. show that multiple organizational features of cortical activity can be traced back to the brainstem and that cortical functional architecture reflects brainstem influence.
https://www.nature.com/articles/s41593-024-01787-0
https://www.nature.com/articles/s41593-024-01787-0
Integrating brainstem and cortical functional architectur...
Hansen et al. used in vivo functional imaging of the huma...
www.nature.com
January 14, 2025 at 3:38 PM
Literature highlight of the week: Hansen et al. show that multiple organizational features of cortical activity can be traced back to the brainstem and that cortical functional architecture reflects brainstem influence.
https://www.nature.com/articles/s41593-024-01787-0
https://www.nature.com/articles/s41593-024-01787-0
Literature highlight of the week: Daume et al., show that activity of hippocampal neurons that are selective for specific image categories in a task performed by humans during working memory maintenance predicts the success of long-term memory...
January 14, 2025 at 3:38 PM
Literature highlight of the week: Daume et al., show that activity of hippocampal neurons that are selective for specific image categories in a task performed by humans during working memory maintenance predicts the success of long-term memory...
Literature highlight of the week: Zheng et al. show that The MD enhances context-relevant recurrent inputs and suppresses context-irrelevant neuronal activities in PFC neurons, making the PFC modular for different temporal contexts...
January 14, 2025 at 3:38 PM
Literature highlight of the week: Zheng et al. show that The MD enhances context-relevant recurrent inputs and suppresses context-irrelevant neuronal activities in PFC neurons, making the PFC modular for different temporal contexts...
Literature highlight of the week: Tian et al. shed light on the neural processes underlying the mental manipulation of multiple items with different ordinal ranks in working...
January 14, 2025 at 3:38 PM
Literature highlight of the week: Tian et al. shed light on the neural processes underlying the mental manipulation of multiple items with different ordinal ranks in working...
Literature highlight of the week: Tang et al. study the roles of the orbitofrontal cortex (OFC), ventral striatum (VS), amygdala (AMY), and mediodorsal thalamus (MDt) in symbolic outcome learning.
https://www.sciencedirect.com/science/article/pii/S0896627324006421?via%3Dihub
https://www.sciencedirect.com/science/article/pii/S0896627324006421?via%3Dihub
ScienceDirect
www.sciencedirect.com
January 14, 2025 at 3:43 PM
Literature highlight of the week: Tang et al. study the roles of the orbitofrontal cortex (OFC), ventral striatum (VS), amygdala (AMY), and mediodorsal thalamus (MDt) in symbolic outcome learning.
https://www.sciencedirect.com/science/article/pii/S0896627324006421?via%3Dihub
https://www.sciencedirect.com/science/article/pii/S0896627324006421?via%3Dihub
Literature highlight of the week: Crawford et al. use two distinct versions of a cognitive effort decision-making paradigm during fMRI and show that the dorsal anterior cingulate cortex is the key locus of cognitive effort-based decision-making in...
January 14, 2025 at 3:43 PM
Literature highlight of the week: Crawford et al. use two distinct versions of a cognitive effort decision-making paradigm during fMRI and show that the dorsal anterior cingulate cortex is the key locus of cognitive effort-based decision-making in...
Literature highlight of the week: Laquitaine et al. reveal the neural and computational mechanisms underlying switching behaviors in humans
https://www.nature.com/articles/s41467-024-52290-w
https://www.nature.com/articles/s41467-024-52290-w
Optimal level of human intracranial theta activity for be...
Direct electrophysiological recordings in the human prefr...
www.nature.com
January 14, 2025 at 3:43 PM
Literature highlight of the week: Laquitaine et al. reveal the neural and computational mechanisms underlying switching behaviors in humans
https://www.nature.com/articles/s41467-024-52290-w
https://www.nature.com/articles/s41467-024-52290-w
Literature highlight of the week: Gava et al. show that plastic organization of hippocampal coactivity supports a network trade-off between robust and flexible computations.
https://www.science.org/doi/10.1126/science.adk9611
https://www.science.org/doi/10.1126/science.adk9611
January 14, 2025 at 3:43 PM
Literature highlight of the week: Gava et al. show that plastic organization of hippocampal coactivity supports a network trade-off between robust and flexible computations.
https://www.science.org/doi/10.1126/science.adk9611
https://www.science.org/doi/10.1126/science.adk9611
Literature highlight of the week: Chen et al., using sequence sorting tasks, show compositional population codes of sequence working memory (SWM) and their well-orchestrated neural dynamics in the frontal cortex, supporting the flexible control of...
January 14, 2025 at 3:43 PM
Literature highlight of the week: Chen et al., using sequence sorting tasks, show compositional population codes of sequence working memory (SWM) and their well-orchestrated neural dynamics in the frontal cortex, supporting the flexible control of...
Literature highlight of the week: New review on how the healthy brain processes numerical information by Andreas Nieder
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
January 14, 2025 at 3:43 PM
Literature highlight of the week: New review on how the healthy brain processes numerical information by Andreas Nieder
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
Literature highlight of the week: New review on how the healthy brain processes numerical information by Andreas Nieder
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
January 14, 2025 at 3:48 PM
Literature highlight of the week: New review on how the healthy brain processes numerical information by Andreas Nieder
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
https://journals.physiology.org/doi/abs/10.1152/physrev.00014.2024
Literature highlight of the week: Rodríguez-Nieto et al. show that increases in excitatory and inhibitory tone were associated with better cognitive performance in young and older adults, respectively, using magnetic resonance...
January 14, 2025 at 3:54 PM
Literature highlight of the week: Rodríguez-Nieto et al. show that increases in excitatory and inhibitory tone were associated with better cognitive performance in young and older adults, respectively, using magnetic resonance...
Literature highlight of the week: Pu et al. show that some dynamic transformations of PFC neuron population-based stimulus representations are not caused by task operations requiring explicit training in male monkeys (Macaca...
January 14, 2025 at 3:54 PM
Literature highlight of the week: Pu et al. show that some dynamic transformations of PFC neuron population-based stimulus representations are not caused by task operations requiring explicit training in male monkeys (Macaca...