European Journal of Neurology
@europeanjournalofneurology.ean.org
The official Journal of the European Academy of Neurology. Covers all areas of clinical and basic research in neurology. #EurJNeurol #OpenAccess
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Long-term follow-up of the RINOMAX trial indicates that rituximab reduces disease activity and treatment burden in new-onset generalized myasthenia gravis compared to placebo.
📚 Read the article by Wu et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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📚 Read the article by Wu et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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December 20, 2025 at 10:01 AM
Long-term follow-up of the RINOMAX trial indicates that rituximab reduces disease activity and treatment burden in new-onset generalized myasthenia gravis compared to placebo.
📚 Read the article by Wu et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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📚 Read the article by Wu et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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While FND symptoms remain stable for most women during pregnancy, a subgroup experiences significant changes or new onset.
📚 Read the article “The Impact of Pregnancy on Functional Neurological Disorder (FND)” by Lehn et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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📚 Read the article “The Impact of Pregnancy on Functional Neurological Disorder (FND)” by Lehn et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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December 18, 2025 at 3:04 PM
While FND symptoms remain stable for most women during pregnancy, a subgroup experiences significant changes or new onset.
📚 Read the article “The Impact of Pregnancy on Functional Neurological Disorder (FND)” by Lehn et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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📚 Read the article “The Impact of Pregnancy on Functional Neurological Disorder (FND)” by Lehn et al. now: onlinelibrary.wiley.com/doi/10.1111/...
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In a retrospective cohort of 134 patients and 46 controls who received iodine contrast, patients with acute ischemic stroke demonstrated increased CSF density.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
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December 16, 2025 at 3:01 PM
In a retrospective cohort of 134 patients and 46 controls who received iodine contrast, patients with acute ischemic stroke demonstrated increased CSF density.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
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Convincing evidence of true remyelination could only be found in preclinical studies investigating glatiramer acetate, teriflunomide, Fingolimod, Siponimod, Ponesimod, and alemtuzumab.
December 13, 2025 at 10:00 AM
Convincing evidence of true remyelination could only be found in preclinical studies investigating glatiramer acetate, teriflunomide, Fingolimod, Siponimod, Ponesimod, and alemtuzumab.
Olfactory dysfunction serves as a multifaceted clinical marker associated with convergent degeneration of nigrostriatal and limbic pathways, offering insights into PD phenotypic variance and its prognostic implications.
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December 11, 2025 at 7:15 PM
Olfactory dysfunction serves as a multifaceted clinical marker associated with convergent degeneration of nigrostriatal and limbic pathways, offering insights into PD phenotypic variance and its prognostic implications.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
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Check out the November issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
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📚 Read now: onlinelibrary.wiley.com/toc/14681331...
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November 29, 2025 at 3:02 PM
Check out the November issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
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📚 Read now: onlinelibrary.wiley.com/toc/14681331...
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⚡️ Steiner et al. report that CIDP burden extends beyond sensorimotor deficits. Motor and cognitive fatigue are clinically relevant and often under-recognized.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #CIDP
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
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November 27, 2025 at 3:03 PM
⚡️ Steiner et al. report that CIDP burden extends beyond sensorimotor deficits. Motor and cognitive fatigue are clinically relevant and often under-recognized.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #CIDP
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #CIDP
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🧪 Horst et al. find that in suspected infectious encephalitis, possible autoimmune encephalitis is uncommon and expanded anti-neuronal antibody panels add limited diagnostic yield.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
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November 25, 2025 at 10:01 AM
🧪 Horst et al. find that in suspected infectious encephalitis, possible autoimmune encephalitis is uncommon and expanded anti-neuronal antibody panels add limited diagnostic yield.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
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🌱 Vitturi et al. report that environmental risks in the first 20 years are key for MS prevention based on a systematic review and meta-analysis.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MS
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November 23, 2025 at 9:01 AM
🌱 Vitturi et al. report that environmental risks in the first 20 years are key for MS prevention based on a systematic review and meta-analysis.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MS
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🧬 Pérez-Pérez and Olmedo-Saura et al. provide an update and roadmap to hereditary choreas.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Chorea
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Chorea
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November 21, 2025 at 3:03 PM
🧬 Pérez-Pérez and Olmedo-Saura et al. provide an update and roadmap to hereditary choreas.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Chorea
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Chorea
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🌙🧠 Zhou et al. suggest that glymphatic function measured with DTI-ALPS (Diffusion tensor image analysis along the perivascular space) links Cerebral Small Vessel Disease burden and sleep quality to cognitive decline.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Sleep
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📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Sleep
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November 18, 2025 at 3:03 PM
🌙🧠 Zhou et al. suggest that glymphatic function measured with DTI-ALPS (Diffusion tensor image analysis along the perivascular space) links Cerebral Small Vessel Disease burden and sleep quality to cognitive decline.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Sleep
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Sleep
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➖ Bjelica et al. show that in adult 5q-SMA on nusinersen treatment, CMAP amplitudes remained stable.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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onlinelibrary.wiley.com
November 15, 2025 at 10:01 AM
➖ Bjelica et al. show that in adult 5q-SMA on nusinersen treatment, CMAP amplitudes remained stable.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #SMA
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🦷 Camps-Plomer et al. report a significant association between periodontitis and migraine in Association Between Migraine and Periodontitis: A Systematic Review and Meta-Analysis.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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November 13, 2025 at 3:04 PM
🦷 Camps-Plomer et al. report a significant association between periodontitis and migraine in Association Between Migraine and Periodontitis: A Systematic Review and Meta-Analysis.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Migraine
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🧫 Obara et al. conclude that NfL is the most validated ALS biomarker in blood and CSF. They warn that single marker use risks misclassification and recommend multimodal approaches.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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November 11, 2025 at 3:04 PM
🧫 Obara et al. conclude that NfL is the most validated ALS biomarker in blood and CSF. They warn that single marker use risks misclassification and recommend multimodal approaches.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #NfL #ALS
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💡 Shimada and Ishikawa et al. find that greater trapezius stiffness aligns with worse TTH severity. Weakness and heavy eyelid sensation may be useful clinical clues.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
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November 8, 2025 at 10:00 AM
💡 Shimada and Ishikawa et al. find that greater trapezius stiffness aligns with worse TTH severity. Weakness and heavy eyelid sensation may be useful clinical clues.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Headache
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Check out the October issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
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📚 Read now: onlinelibrary.wiley.com/toc/14681331...
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October 31, 2025 at 9:02 AM
Check out the October issue of European Journal of Neurology!
📚 Read now: onlinelibrary.wiley.com/toc/14681331...
#EurJNeurol #Neurology #EJoN
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📚 Read now: onlinelibrary.wiley.com/toc/14681331...
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💡 Søborg et al. demonstrate that PACAP-38 levels are elevated across all cluster headache states, supporting PACAP as a therapeutic target while noting no clear correlation with CGRP.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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October 28, 2025 at 3:05 PM
💡 Søborg et al. demonstrate that PACAP-38 levels are elevated across all cluster headache states, supporting PACAP as a therapeutic target while noting no clear correlation with CGRP.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #PACAP #ClusterHeadache
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🗣️ Hossain et al. show that shorter disease duration associates with behavioral dyscontrol, frontal lobe involvement, and higher 4-repeat tau burden in the locus coeruleus.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
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October 25, 2025 at 10:02 AM
🗣️ Hossain et al. show that shorter disease duration associates with behavioral dyscontrol, frontal lobe involvement, and higher 4-repeat tau burden in the locus coeruleus.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Apraxia
@ean.org #WileyNeuro
🩺 Doneddu et al. demonstrate that incorporating additional electrophysiological parameters improves diagnostic sensitivity without compromising specificity, expanding the recognized spectrum of MMN abnormalities.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
@ean.org #WileyNeuro
October 23, 2025 at 3:05 PM
🩺 Doneddu et al. demonstrate that incorporating additional electrophysiological parameters improves diagnostic sensitivity without compromising specificity, expanding the recognized spectrum of MMN abnormalities.
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Neuropathy
@ean.org #WileyNeuro
⚡ Chemaly & Kuchenbuch et al. show that CBD reduces seizures and improves comorbidities, with strong 18-month retention supporting its efficacy and tolerability beyond approved indications.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
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October 21, 2025 at 3:00 PM
⚡ Chemaly & Kuchenbuch et al. show that CBD reduces seizures and improves comorbidities, with strong 18-month retention supporting its efficacy and tolerability beyond approved indications.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Epilepsy
@ean.org #WileyNeuro
❤️ Galea et al. find that LAAC is safe and feasible, with lower recurrent stroke rates than continued OAC alone, suggesting additive protection pending confirmation from randomized trials.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
@ean.org #WileyNeuro
October 18, 2025 at 9:02 AM
❤️ Galea et al. find that LAAC is safe and feasible, with lower recurrent stroke rates than continued OAC alone, suggesting additive protection pending confirmation from randomized trials.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Stroke
@ean.org #WileyNeuro
🧠 Caestecker et al. review in “The Locus Coeruleus–Noradrenergic System in the Healthy and Diseased Brain” how integrating anatomical, neurochemical, and functional data clarifies the LCNA system’s central role and therapeutic potential
📚 onlinelibrary.wiley.com/doi/10.1111/...
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📚 onlinelibrary.wiley.com/doi/10.1111/...
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October 16, 2025 at 3:45 PM
🧠 Caestecker et al. review in “The Locus Coeruleus–Noradrenergic System in the Healthy and Diseased Brain” how integrating anatomical, neurochemical, and functional data clarifies the LCNA system’s central role and therapeutic potential
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/10.1111/...
@ean.org #WileyNeuro
💪 Popkirov reports in that reduced grip strength reflects altered higher-order motor control, challenging its value as a biomarker of peripheral dysfunction.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
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📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
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October 14, 2025 at 4:05 PM
💪 Popkirov reports in that reduced grip strength reflects altered higher-order motor control, challenging its value as a biomarker of peripheral dysfunction.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #MECFS
@ean.org #WileyNeuro
🧩 Marini et al. show in that the insular knife-cut sign on MRI strongly predicts HSVE and should raise immediate suspicion even when other tests are inconclusive.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
@ean.org #WileyNeuro
October 12, 2025 at 9:00 AM
🧩 Marini et al. show in that the insular knife-cut sign on MRI strongly predicts HSVE and should raise immediate suspicion even when other tests are inconclusive.
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
@ean.org #WileyNeuro
📚 Read now: onlinelibrary.wiley.com/doi/10.1111/...
#Neurology #Encephalitis
@ean.org #WileyNeuro
🧪 Hegen et al. demonstrate that the κ-FLC index closely aligns with OCB, with discordant results mainly in the gray zone. A reflex testing approach using κ-FLC first and OCB for gray-zone cases appears reasonable.
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
@ean.org #WileyNeuro
October 10, 2025 at 3:05 PM
🧪 Hegen et al. demonstrate that the κ-FLC index closely aligns with OCB, with discordant results mainly in the gray zone. A reflex testing approach using κ-FLC first and OCB for gray-zone cases appears reasonable.
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
@ean.org #WileyNeuro
📚 onlinelibrary.wiley.com/doi/full/10....
#Neuroimmunology
@ean.org #WileyNeuro