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Epigenome Technologies @epigenometech.bsky.social · 3h

Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

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Epigenome Technologies @epigenometech.bsky.social · 8h

Epigenetics Update - A cGAS-mediated mechanism in naked mole-rats potentiates DNA repair and delays aging bit.ly/4q4UMDo

Ying Jiang and Zhiyong Mao reporting in Science

#Epigenetics #Chromatin #DNARepair #Longevity #Aging
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Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 12h

Epigenetics Update - Early-life ketone body signalling promotes beige fat biogenesis through changes in histone acetylome and β-hydroxybutyrylome go.nature.com/3IDbokZ

#Epigenetics #Metabolism #Chromatin

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Gain deeper insights into gene regulation with epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 1d

Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics

bit.ly/4kgWMF3

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Epigenome Technologies @epigenometech.bsky.social · 1d

Epigenetics Update - Reporter CRISPR screens decipher cis-regulatory and trans-regulatory principles at the Xist locus go.nature.com/42vdHgt

Edda G. Schulz reporting in NSMB

#Epigenetics #CRISPR #Chromatin #Xist
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Discover the breakthrough at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 1d

Epigenetics News - Strong friendships may literally slow aging at the cellular level bit.ly/3IuMDaA

#Epigenetics #News #Aging #EpigeneticAging

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High-resolution insights without cell sorting; epigenometech.com

Strong friendships may literally slow aging at the cellular level

Scientists discovered that lifelong social support can slow biological aging. Using DNA-based “epigenetic clocks,” they found that people with richer, more sustained relationships showed younger biolo...

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Epigenome Technologies @epigenometech.bsky.social · 4d

Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks
from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

bit.ly/3HWFoaw

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Epigenome Technologies @epigenometech.bsky.social · 4d

Epigenetics News - Longevity May Be Passed From Parents to Children Through the Epigenome bit.ly/42ZE4v5

#Epigenetics #News #Aging #EpigeneticAging #Inheritance

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Empower your research with high-res epigenetic insights at epigenometech.com

Longevity May Be Passed From Parents to Children Through the Epigenome | HHMI

New research led by HHMI Janelia Research Campus Senior Group Leader Meng Wang provides insights into how changes that help organisms deal with environmental stress are conferred to their offspring.

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Epigenome Technologies @epigenometech.bsky.social · 4d

Epigenetics News - Study Finds Restoring Order to Dividing Cancer Cells May Prevent Metastasis bit.ly/4nCrJpe

#Epigenetics #News #TNBC #EZH2 #Cancer
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Perfect for cancer, immunology, and aging research; epigenometech.com

Study Finds Restoring Order to Dividing Cancer Cells May Prevent Metastasis

Triple negative breast cancer (TNBC) is one of the most aggressive and hardest to treat breast cancers, but a new study led by Weill Cornell Medicine suggests a way to stop it from spreading.

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Epigenome Technologies @epigenometech.bsky.social · 5d

New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks

#Epigenetics #SingleCell #PairedTag #Multiomics

Find out more at: bit.ly/4efqM1Y

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Epigenome Technologies @epigenometech.bsky.social · 5d

Epigenetics News - Epigenetic Switches Behind PFAS Cell Damage Identified bit.ly/46BYehb

#Epigenetics #News #PFAS #DNAme
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Gain deeper insights into gene regulation; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 5d

Epigenetics Update - Plant mobile domain protein–DNA motif modules counteract Polycomb silencing to stabilize gene expression go.nature.com/3IzfbQe

#Epigenetics #Chromatin #Plants #Polycomb
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Discover the breakthrough at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 6d

Check out our blog article on a new #SingleCell study employing #PairedTag technology! bit.ly/4nDzyL9

“Simultaneous Single-cell Epigenetic and Transcriptomic Analysis via Paired-Tag Highlights the Postnatal Impact of Prenatal Vaping”

#EpigenomeTech #PairedTag #Chromatin #Epigenetics #Vaping

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Epigenome Technologies @epigenometech.bsky.social · 6d

Epigenetics Update - Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer go.nature.com/4nBP760

#Epigenetics #Chromatin #ProstateCancer #Cancer
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High-resolution insights without cell sorting; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 6d

Epigenetics Update - ATP-dependent remodeling of chromatin condensates reveals distinct mesoscale outcomes bit.ly/4pXa9hi

Vijay Ramani and Geeta J. Narlikar (UCSF) reporting in Science

#Epigenetics #Chromatin
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Empower your research with high-res epigenetic insights at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 7d

We are proud to announce that the Epigenome Technologies CTO, Chris Hartl, will be discussing Paired-Tag at the @upenn.edu Epigenetics Institute on Thursday, 9th October!

We hope to see you there! bit.ly/4pT78yl

#EpigenomeTech #PairedTag #SingleCell #Epigenetics

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Epigenome Technologies @epigenometech.bsky.social · 7d

Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service

Our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4kPxe2i

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Epigenome Technologies @epigenometech.bsky.social · 7d

Epigenetics Update - Remodelling bivalent chromatin is essential for mouse peri-implantation embryogenesis go.nature.com/4o38m8G

#Epigenetics #Bivalency #Chromatin #Embryogenesis
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Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 7d

Epigenetics Update - Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer bit.ly/3IDQSAA

Lihui Wang reporting in PNAS

#Epigenetics #Crotonylation #Cancer
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Gain deeper insights into gene regulation; epigenometech.com

Activation of epigenetic reprogramming via crotonylation overcomes resistance to EGFR-TKI therapy in lung cancer | PNAS

Posttranslational modifications (PTMs) on histones play critical roles in cellular processes, including gene expression and tumorigenesis. However,...

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Epigenome Technologies @epigenometech.bsky.social · 8d

We are proud to announce that the Epigenome Technologies CTO, Chris Hartl, will be discussing Paired-Tag at @washumedicine.bsky.social on Wednesday, 8th October!

We hope to see you there! bit.ly/4mJk3A4

#EpigenomeTech #PairedTag #SingleCell #Epigenetics

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Epigenome Technologies @epigenometech.bsky.social · 8d

New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit

Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4lquJDv

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Epigenome Technologies @epigenometech.bsky.social · 8d

Epigenetics Update – Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates go.nature.com/4mPi3X7

#Epigenetics #GeneSilencing #EpigeneticEditing

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Discover the breakthrough at epigenometech.com

Epigenome Technologies @epigenometech.bsky.social · 8d

Epigenetics Update – Phase-separated NDF−FACT condensates facilitate transcription elongation on chromatin go.nature.com/4mDh6AX

Carlos Bustamante and Jia Fei in Nat Cell Biol

#Epigenetics #Chromatin
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High-resolution insights without cell sorting; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 11d

We are proud to announce that the Epigenome Technologies CTO Chris Hartl will be discussing Paired-Tag at the @upenn.edu Epigenetics Institute on Thursday 9th October!

We hope to see you there! bit.ly/4pT78yl

#EpigenomeTech #PairedTag #SingleCell #Epigenetics

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Epigenome Technologies @epigenometech.bsky.social · 11d

Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

bit.ly/4kgWMF3

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