Epigenome Technologies
epigenometech.bsky.social
Epigenome Technologies
@epigenometech.bsky.social
Epigenome Technologies, pioneering in epigenetic and single-cell analysis, offers advanced assay kits and optimization services.
Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in individual brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers

bit.ly/4kgWMF3
November 28, 2025 at 3:38 PM
Epigenetics Update - NSD2 targeting reverses plasticity and drug resistance in prostate cancer go.nature.com/4imgShn

Chao Lu and Michael M. Shen (Columbia University) in Nature

#Epigenetics #ProstateCancer #NSD2 #H3K36me2
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Empower your research with: epigenometech.com
November 28, 2025 at 11:32 AM
Epigenetics Update - Iron homeostasis and cell clonality drive cancer-associated intestinal DNA methylation drift in aging go.nature.com/4ijta9Y

Francesco Neri reporting in Nat Aging

#Epigenetics #DNAm #Cancer #Aging
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 28, 2025 at 8:50 AM
Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements

#Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics

bit.ly/4kgWMF3
November 27, 2025 at 4:46 PM
Epigenetics Review - Epigenetic editing: from concept to clinic go.nature.com/3LZJjpi

Marianne G. Rots (University of Groningen) reporting in Nat Rev Drug Disc

#Epigenetics #Review #EpigeneticEditing
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Gain deeper insights into gene regulation; epigenometech.com
Epigenetic editing: from concept to clinic - Nature Reviews Drug Discovery
Epigenetic editing has emerged as a powerful hit-and-run approach to precise modification of gene expression without altering the underlying DNA sequence. This Review explores the therapeutic potentia...
go.nature.com
November 27, 2025 at 12:11 PM
Epigenetics Update - Heterochromatin boundaries maintain centromere position, size and number go.nature.com/3MnWTTh

Lars E. T. Jansen (University of Oxford) reporting in NSMB

#Epigenetics #Heterochromatin #Chromatin
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Discover the breakthrough at epigenometech.com
November 27, 2025 at 8:46 AM
New Epigenome Technologies Blog post! bit.ly/4oVHGY9

"Integrating Nuclear Mechanics, Shape, and Volume with Chromatin State to Control Cell Fate Transitioning"

Based on a Nature Cell Biology paper from Kate Miroshnikova and Sara Wickström

#Epigenetics #Blog #EpigenomeTech #Chromatin
November 26, 2025 at 4:03 PM
Epigenetics Update - Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture bit.ly/43T1JOp

Yohsuke T. Fukai/Kyogo Kawaguchi in Sci Adv

#Epigenetics #Chromatin #HistoneAcetylation
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High-resolution insights without cell sorting; epigenometech.com
November 26, 2025 at 12:22 PM
Epigenetics Update - Hexokinase 2-mediated histone H3K18la promotes PAI-1-dependent thrombosis in acute myeloid leukemia via tumor-endothelial crosstalk go.nature.com/43GzkLr

#Epigenetics #AML #Cancer #Lactylation
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Empower your research with high-res epigenetic insights at epigenometech.com
November 26, 2025 at 9:06 AM
Epigenome Technologies offers an end-to-end single-cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA and epigenetic marks (we run the workflow on your samples) from preparation to data analysis

#Epigenetics #SingleCell #PairedTag #Multiomics

bit.ly/3HWFoaw
November 25, 2025 at 4:39 PM
Epigenetics Update - A chromatin-linked CPL2–PHD2/3 module sustains multiple DNA methylation pathways and Polycomb silencing bit.ly/3LYXKd5

Jian-Kang Zhu reporting in PNAS

#Epigenetics #Chromatin #DNAm #Polycomb #Plants
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 25, 2025 at 1:09 PM
Epigenetics Update - Engineered chromatin readers track damaged chromatin dynamics in live cells and animals go.nature.com/4ikfHPs

Richard Cardoso da Silva and Tuncay Baubec reporting in Nat Commun

#Epigenetics #Chromatin
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Gain deeper insights into gene regulation; epigenometech.com
November 25, 2025 at 8:28 AM
New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks

#Epigenetics #SingleCell #PairedTag #Multiomics

Find out more at: bit.ly/4efqM1Y
November 24, 2025 at 4:15 PM
Epigenetics Update - Addressing the specific roles of histone modifications in transcriptional repression go.nature.com/4pqQXXQ

Kristian Helin (MSKCC/University of Copenhagen) reporting in Nat Commun

#Epigenetics #HisMods #Chromatin
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Discover the breakthrough at epigenometech.com
November 24, 2025 at 12:10 PM
Epigenetics News - Epigenetic changes regulate gene expression, but what regulates epigenetics? bit.ly/4oc4NMI

A paper from Guanghui Xu and Julie Law in Nat Cell Biol

#Epigenetics #News #Plants
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High-resolution insights without cell sorting; epigenometech.com
Epigenetic changes regulate gene expression, but what regulates epigenetics? - Salk Institute for Biological Studies
LA JOLLA—All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are express...
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November 24, 2025 at 8:19 AM
Learn more about single-cell epigenetic profiling by downloading our guide to single-cell CUT&Tag and single-cell Paired-Tag, which provides comparisons to other methods and bioinformatic insight!

bit.ly/4r7CGRD

#Epigenetics #Multiomics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag
November 21, 2025 at 3:03 PM
Epigenetics Update – Transcription factors instruct DNA methylation patterns in plant reproductive tissues go.nature.com/4rbGrFR

Julie A. Law reporting in Nat Cell Biol

#Epigenetics #DNAm #Plants #Chromatin
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 21, 2025 at 11:47 AM
Epigenetics Preprint - Brain Region-Specific Epigenomic Reorganization and Altered Cell States in Alzheimer’s Disease bit.ly/4rfHt3M

Bradley T. Hyman (Harvard) and Joseph R. Ecker (Salk)

#Epigenetics #Preprint #AlzheimersDisease
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Gain deeper insights into gene regulation; epigenometech.com
November 21, 2025 at 8:50 AM
Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service

Our expert scientists run the entire workflow on your samples - from preparation to data analysis

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4kPxe2i
November 20, 2025 at 4:26 PM
Epigenetics Update - Genetic elements promote retention of extrachromosomal DNA in cancer cells go.nature.com/4rqIyWz

Paul S. Mischel and Howard Y. Chang (Stanford University) reporting in Nature

#Epigenetics #ecDNA #DNAm
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Discover the breakthrough at epigenometech.com
November 20, 2025 at 1:04 PM
Epigenetics Update - Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk bit.ly/47Nroui

Andrew J. Spakowitz (Stanford University) reporting in PNAS
#Epigenetics #Chromatin #Models

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High-resolution insights without cell sorting; epigenometech.com
Physical models reveal indirect reader protein interactions that facilitate epigenetic crosstalk | PNAS
The spatial organization of chromatin is governed by epigenetic factors, including epigenetic marks and the reader proteins that bind them. By dict...
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November 20, 2025 at 8:40 AM
New Epigenome Technologies Blog post! bit.ly/47LGMay

"Chromatin States in Pancreatic Ductal Adenocarcinoma Control Metastatic Spread"

Based on a Nature Cancer paper from Kaloyan M. Tsanov and Scott W. Lowe

#Epigenetics #Blog #EpigenomeTech #PDAC #Metastasis #Chromatin
November 19, 2025 at 5:02 PM
Epigenetics Update - High-throughput capture of actively transcribed region-interacting sequences reveals an intricate promoter-centered regulatory network bit.ly/448YNNG

#Epigenetics #Chromatin #ChromatinConformation
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Empower your research with high-res epigenetic insights at epigenometech.com
November 19, 2025 at 12:41 PM
Epigenetics Update - Disentangling the architectural and non-architectural functions of CTCF and cohesin in gene regulation go.nature.com/488ztZx

#Epigenetics #CTCF #Chromatin #Cohesin
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Perfect for cancer, immunology, and aging research; epigenometech.com
November 19, 2025 at 8:07 AM
New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit!

Fully compatible with 10x Chromium® (ATAC) or Fluent PiP-seq®

#Epigenetics #SingleCell #CUTandTag

Find out more at: bit.ly/4lquJDv
November 18, 2025 at 3:58 PM