Dr Graham Lloyd-Jones
@drgrahamlj.bsky.social
Consultant Radiologist UK.
Medical imaging educator.
Founder/Director of radiologymasterclass.co.uk.
Investigating links between poor oral health and systemic disease | oral microbiome | COVID-19 & LongCOVID.
Oral Health Section Editor - Springer Nature
Medical imaging educator.
Founder/Director of radiologymasterclass.co.uk.
Investigating links between poor oral health and systemic disease | oral microbiome | COVID-19 & LongCOVID.
Oral Health Section Editor - Springer Nature
Pinned
Here's my take on #COVID-19 (the disease not the pandemic).
It's not what you think it is ...
A thread 👇
1/23
It's not what you think it is ...
A thread 👇
1/23
Reposted by Dr Graham Lloyd-Jones
Published today after 2years of work behind the scenes by us at WHN/DELPHI Executive team : Our Global Expert DELPHI Consensus document on Long Covid. 179 Experts from 28 countries around the Globe Participated. Please share. Happy Easter!
link.springer.com/article/10.1...
link.springer.com/article/10.1...
April 21, 2025 at 12:18 AM
Published today after 2years of work behind the scenes by us at WHN/DELPHI Executive team : Our Global Expert DELPHI Consensus document on Long Covid. 179 Experts from 28 countries around the Globe Participated. Please share. Happy Easter!
link.springer.com/article/10.1...
link.springer.com/article/10.1...
Dear #MedBlueSky
Black and white EITHER/OR debates limit us.
Nuanced AND/BOTH debates provide answers.
Let's not oversimplify the human body. It is too complicated to be understood in terms of binary EITHER/OR stances.
The nuance of AND/BOTH is the way forward.
Thanks
Black and white EITHER/OR debates limit us.
Nuanced AND/BOTH debates provide answers.
Let's not oversimplify the human body. It is too complicated to be understood in terms of binary EITHER/OR stances.
The nuance of AND/BOTH is the way forward.
Thanks
April 18, 2025 at 4:38 PM
Dear #MedBlueSky
Black and white EITHER/OR debates limit us.
Nuanced AND/BOTH debates provide answers.
Let's not oversimplify the human body. It is too complicated to be understood in terms of binary EITHER/OR stances.
The nuance of AND/BOTH is the way forward.
Thanks
Black and white EITHER/OR debates limit us.
Nuanced AND/BOTH debates provide answers.
Let's not oversimplify the human body. It is too complicated to be understood in terms of binary EITHER/OR stances.
The nuance of AND/BOTH is the way forward.
Thanks
If in Dec 2020 you had told me it would take until April 2021 to get my #COVID research published, I’d have been disappointed.
It has now been published (April 2025), 4 years later.
bit.ly/4j6fIpx
👇
Here's my epic COVID-19 failure story …
Long thread 1/25
It has now been published (April 2025), 4 years later.
bit.ly/4j6fIpx
👇
Here's my epic COVID-19 failure story …
Long thread 1/25
April 12, 2025 at 11:36 PM
If in Dec 2020 you had told me it would take until April 2021 to get my #COVID research published, I’d have been disappointed.
It has now been published (April 2025), 4 years later.
bit.ly/4j6fIpx
👇
Here's my epic COVID-19 failure story …
Long thread 1/25
It has now been published (April 2025), 4 years later.
bit.ly/4j6fIpx
👇
Here's my epic COVID-19 failure story …
Long thread 1/25
Only for doctors who might be interested in biological mechanisms of cardiovascular risk…
But it can’t be important coz it’s about the mouth. And we all know the mouth is not really a part of the body, right?
#OralMicrobiome
#EnteroSalivaryNOPathway
www.ahajournals.org/doi/10.1161/...
But it can’t be important coz it’s about the mouth. And we all know the mouth is not really a part of the body, right?
#OralMicrobiome
#EnteroSalivaryNOPathway
www.ahajournals.org/doi/10.1161/...
Nitrite Generating and Depleting Capacity of the Oral Microbiome and Cardiometabolic Risk: Results from ORIGINS | Journal of the American Heart Association
www.ahajournals.org
March 29, 2025 at 12:26 AM
Only for doctors who might be interested in biological mechanisms of cardiovascular risk…
But it can’t be important coz it’s about the mouth. And we all know the mouth is not really a part of the body, right?
#OralMicrobiome
#EnteroSalivaryNOPathway
www.ahajournals.org/doi/10.1161/...
But it can’t be important coz it’s about the mouth. And we all know the mouth is not really a part of the body, right?
#OralMicrobiome
#EnteroSalivaryNOPathway
www.ahajournals.org/doi/10.1161/...
Only of interest to anyone with a mouth and a brain they care about ...
👇👇👇
Oral Microbiome and Alzheimer’s Disease
Wan and Fan 2023
pmc.ncbi.nlm.nih.gov/articles/PMC10609607/
👇👇👇
Oral Microbiome and Alzheimer’s Disease
Wan and Fan 2023
pmc.ncbi.nlm.nih.gov/articles/PMC10609607/
Oral Microbiome and Alzheimer’s Disease
The accumulation of amyloid-beta plaques in the brain is a central pathological feature of Alzheimer’s disease. It is believed that amyloid responses may be a result of the host immune response to pat...
pmc.ncbi.nlm.nih.gov
March 21, 2025 at 11:59 AM
Only of interest to anyone with a mouth and a brain they care about ...
👇👇👇
Oral Microbiome and Alzheimer’s Disease
Wan and Fan 2023
pmc.ncbi.nlm.nih.gov/articles/PMC10609607/
👇👇👇
Oral Microbiome and Alzheimer’s Disease
Wan and Fan 2023
pmc.ncbi.nlm.nih.gov/articles/PMC10609607/
Reposted by Dr Graham Lloyd-Jones
A Question to Which the Answer is Yes #QTWTAIY
Industry have been flogging products sugarier than Coke to of infants.
We lifted the lid on this scandal in 2022.
👇
https://www.theguardian.com/society/2025/mar/15/ultra-processed-babies-are-toddler-snacks-one-of-the-great-food-scandals-of-our-time
Industry have been flogging products sugarier than Coke to of infants.
We lifted the lid on this scandal in 2022.
👇
https://www.theguardian.com/society/2025/mar/15/ultra-processed-babies-are-toddler-snacks-one-of-the-great-food-scandals-of-our-time
March 15, 2025 at 5:16 PM
A Question to Which the Answer is Yes #QTWTAIY
Industry have been flogging products sugarier than Coke to of infants.
We lifted the lid on this scandal in 2022.
👇
https://www.theguardian.com/society/2025/mar/15/ultra-processed-babies-are-toddler-snacks-one-of-the-great-food-scandals-of-our-time
Industry have been flogging products sugarier than Coke to of infants.
We lifted the lid on this scandal in 2022.
👇
https://www.theguardian.com/society/2025/mar/15/ultra-processed-babies-are-toddler-snacks-one-of-the-great-food-scandals-of-our-time
Reposted by Dr Graham Lloyd-Jones
🥣 Did you know only 3% of breakfast cereals and 5% of yogurts marketed to children are low in sugar?
We'd like retailers to reformulate products and stop marketing unhealthy food to children.
Read more: bit.ly/3PR0Gal
#BrokenPlate #HFSS
We'd like retailers to reformulate products and stop marketing unhealthy food to children.
Read more: bit.ly/3PR0Gal
#BrokenPlate #HFSS
March 6, 2025 at 4:07 PM
🥣 Did you know only 3% of breakfast cereals and 5% of yogurts marketed to children are low in sugar?
We'd like retailers to reformulate products and stop marketing unhealthy food to children.
Read more: bit.ly/3PR0Gal
#BrokenPlate #HFSS
We'd like retailers to reformulate products and stop marketing unhealthy food to children.
Read more: bit.ly/3PR0Gal
#BrokenPlate #HFSS
It is not possible to understand #Alzheimer’s disease without understanding the involvement of #OralMicrobiome pathogens.
Not only is Alzheimer’s a disease, it is a microbial ecosystem.
#PGingivalis
#OralBacterialTranslocation
#OuterMembraneVesicles
#Lactoferrin
#Neuroinflammation
#IronMetabolism
Not only is Alzheimer’s a disease, it is a microbial ecosystem.
#PGingivalis
#OralBacterialTranslocation
#OuterMembraneVesicles
#Lactoferrin
#Neuroinflammation
#IronMetabolism
March 6, 2025 at 12:57 AM
It is not possible to understand #Alzheimer’s disease without understanding the involvement of #OralMicrobiome pathogens.
Not only is Alzheimer’s a disease, it is a microbial ecosystem.
#PGingivalis
#OralBacterialTranslocation
#OuterMembraneVesicles
#Lactoferrin
#Neuroinflammation
#IronMetabolism
Not only is Alzheimer’s a disease, it is a microbial ecosystem.
#PGingivalis
#OralBacterialTranslocation
#OuterMembraneVesicles
#Lactoferrin
#Neuroinflammation
#IronMetabolism
Some Sunday listening for you.
In this BBC Radio 4 programme I talk about the importance of oral health for the health of your body.
Presented by @carolinesteel.bsky.social and featuring her visit to Salisbury Hospital
👇👇👇
bbc.co.uk/sounds/play/m00283bm
In this BBC Radio 4 programme I talk about the importance of oral health for the health of your body.
Presented by @carolinesteel.bsky.social and featuring her visit to Salisbury Hospital
👇👇👇
bbc.co.uk/sounds/play/m00283bm
Mouth Organ - BBC Sounds
Caroline Steel finds out why we need to put the mouth back in the body.
bbc.co.uk
February 23, 2025 at 8:14 AM
Some Sunday listening for you.
In this BBC Radio 4 programme I talk about the importance of oral health for the health of your body.
Presented by @carolinesteel.bsky.social and featuring her visit to Salisbury Hospital
👇👇👇
bbc.co.uk/sounds/play/m00283bm
In this BBC Radio 4 programme I talk about the importance of oral health for the health of your body.
Presented by @carolinesteel.bsky.social and featuring her visit to Salisbury Hospital
👇👇👇
bbc.co.uk/sounds/play/m00283bm
Reposted by Dr Graham Lloyd-Jones
I’m on Radio 4 NOW learning about how the bacteria in our mouths affect our overall health. There are links between our mouth health and diabetes and Alzheimer’s 🤯
With @drgrahamlj.bsky.social
www.bbc.co.uk/programmes/m...
With @drgrahamlj.bsky.social
www.bbc.co.uk/programmes/m...
BBC Radio 4 - Mouth Organ
Caroline Steel finds out why we need to put the mouth back in the body.
www.bbc.co.uk
February 19, 2025 at 3:48 PM
I’m on Radio 4 NOW learning about how the bacteria in our mouths affect our overall health. There are links between our mouth health and diabetes and Alzheimer’s 🤯
With @drgrahamlj.bsky.social
www.bbc.co.uk/programmes/m...
With @drgrahamlj.bsky.social
www.bbc.co.uk/programmes/m...
Today is the 4th anniversary of the first publication of the oro-vasculo-pulmonary route hypothesis of spread of #SARS2 to the lungs from the mouth via the bloodstream in people with #COVID.
First published informally here - radiologymasterclass.co.uk/tutorials/co...
1/4
First published informally here - radiologymasterclass.co.uk/tutorials/co...
1/4
February 20, 2025 at 10:29 PM
Today is the 4th anniversary of the first publication of the oro-vasculo-pulmonary route hypothesis of spread of #SARS2 to the lungs from the mouth via the bloodstream in people with #COVID.
First published informally here - radiologymasterclass.co.uk/tutorials/co...
1/4
First published informally here - radiologymasterclass.co.uk/tutorials/co...
1/4
What's bad about the lack of funding into dentistry is that the message of @eddiecrouch.bsky.social is being ignored. Here he tells us how oral health is linked with general health.
Dental/oral health is not an add-on extra to your health, it is a foundation of your health.
Oral disease kills!
Dental/oral health is not an add-on extra to your health, it is a foundation of your health.
Oral disease kills!
The Labour Party went into the 2024 election promising to reform the discredited NHS contract fuelling the current crisis
According to @thebda.bsky.social there has been no material progress to date & its deeply concerned the Treasury is now standing in the way of progress
youtu.be/Hu0Okad5O1w?...
According to @thebda.bsky.social there has been no material progress to date & its deeply concerned the Treasury is now standing in the way of progress
youtu.be/Hu0Okad5O1w?...
THE SHOCKING state of NHS dentistry in England has today - again - been laid bare
YouTube video by Peter Stefanovic
youtu.be
February 12, 2025 at 6:41 PM
What's bad about the lack of funding into dentistry is that the message of @eddiecrouch.bsky.social is being ignored. Here he tells us how oral health is linked with general health.
Dental/oral health is not an add-on extra to your health, it is a foundation of your health.
Oral disease kills!
Dental/oral health is not an add-on extra to your health, it is a foundation of your health.
Oral disease kills!
'Time to put your money where your mouth is'
For anyone working in the field of health inequalities, this report from @Economist.com(@EconomistImpact) is a must.
👇👇👇👇👇👇👇
bit.ly/3WLjc7Z
Thread of highlights ...
1/14
For anyone working in the field of health inequalities, this report from @Economist.com(@EconomistImpact) is a must.
👇👇👇👇👇👇👇
bit.ly/3WLjc7Z
Thread of highlights ...
1/14
February 6, 2025 at 3:47 PM
'Time to put your money where your mouth is'
For anyone working in the field of health inequalities, this report from @Economist.com(@EconomistImpact) is a must.
👇👇👇👇👇👇👇
bit.ly/3WLjc7Z
Thread of highlights ...
1/14
For anyone working in the field of health inequalities, this report from @Economist.com(@EconomistImpact) is a must.
👇👇👇👇👇👇👇
bit.ly/3WLjc7Z
Thread of highlights ...
1/14
Reposted by Dr Graham Lloyd-Jones
Today we’re in Westminster, showing MPs how many teeth are extracted from children in their communities.
It's the result of a toxic food environment, an access crisis, and a long-term failure to grasp the nettle on prevention.
Our children deserve better.
It's the result of a toxic food environment, an access crisis, and a long-term failure to grasp the nettle on prevention.
Our children deserve better.
February 5, 2025 at 12:53 PM
Today we’re in Westminster, showing MPs how many teeth are extracted from children in their communities.
It's the result of a toxic food environment, an access crisis, and a long-term failure to grasp the nettle on prevention.
Our children deserve better.
It's the result of a toxic food environment, an access crisis, and a long-term failure to grasp the nettle on prevention.
Our children deserve better.
Interesting
‘Compared with the pre-COVID condition, the COVID group had greater severity of inattention, somatic complaints, thought problems, internalizing problems, poor school functions, and interaction problems with their parents in the post-COVID condition’
#LongCovid #LongCovidKids
#LongCovid #LongCovidKids
January 22, 2025 at 5:52 PM
Interesting
Reposted by Dr Graham Lloyd-Jones
🚨1/5. Some findings from the 2024 National GP Patient Survey:
⚠️ 4.6% of people have #LongCovid
⚠️ In addition, 9.4% were not sure if they have Long Covid
⚠️ And 1.2% preferred not to say
(Question asked of 692,751 patients)
#CovidIsNotOver
Link⬇️
⚠️ 4.6% of people have #LongCovid
⚠️ In addition, 9.4% were not sure if they have Long Covid
⚠️ And 1.2% preferred not to say
(Question asked of 692,751 patients)
#CovidIsNotOver
Link⬇️
January 20, 2025 at 11:17 AM
🚨1/5. Some findings from the 2024 National GP Patient Survey:
⚠️ 4.6% of people have #LongCovid
⚠️ In addition, 9.4% were not sure if they have Long Covid
⚠️ And 1.2% preferred not to say
(Question asked of 692,751 patients)
#CovidIsNotOver
Link⬇️
⚠️ 4.6% of people have #LongCovid
⚠️ In addition, 9.4% were not sure if they have Long Covid
⚠️ And 1.2% preferred not to say
(Question asked of 692,751 patients)
#CovidIsNotOver
Link⬇️
Are there any other radiologists out there working on disease prevention? If so, please get in contact.
(I don’t mean screening for disease, I mean stopping disease from happening.)
(I don’t mean screening for disease, I mean stopping disease from happening.)
January 15, 2025 at 12:29 PM
Are there any other radiologists out there working on disease prevention? If so, please get in contact.
(I don’t mean screening for disease, I mean stopping disease from happening.)
(I don’t mean screening for disease, I mean stopping disease from happening.)
This is what I said about the lung disease of #COVID-19 in 2020.
2020!
They gave me 10 minutes (for which I was grateful)
And now…
Now, I stand by every word.
COVID-19 lung disease was not pneumonia!
This knowledge should have changed everything, but didn’t.
youtu.be/2jROYLwUK20
2020!
They gave me 10 minutes (for which I was grateful)
And now…
Now, I stand by every word.
COVID-19 lung disease was not pneumonia!
This knowledge should have changed everything, but didn’t.
youtu.be/2jROYLwUK20
COVID-19 Lung Disease: A Pulmonary Vasculopathy
YouTube video by Radiology Masterclass
youtu.be
December 7, 2024 at 2:40 AM
This is what I said about the lung disease of #COVID-19 in 2020.
2020!
They gave me 10 minutes (for which I was grateful)
And now…
Now, I stand by every word.
COVID-19 lung disease was not pneumonia!
This knowledge should have changed everything, but didn’t.
youtu.be/2jROYLwUK20
2020!
They gave me 10 minutes (for which I was grateful)
And now…
Now, I stand by every word.
COVID-19 lung disease was not pneumonia!
This knowledge should have changed everything, but didn’t.
youtu.be/2jROYLwUK20
4k words added to a chapter on #T2DM written today (will need editing).
Simplified summary - diabetes is all about oral biology/health.
#GumDisease
#Periodontitis
#Pgingivalis
#InsulinResitance
#SystemicInflammation
#OralBacteriaBloodstreamTranslocation
#InsulinReceptorDamage
#Epigenetics
Simplified summary - diabetes is all about oral biology/health.
#GumDisease
#Periodontitis
#Pgingivalis
#InsulinResitance
#SystemicInflammation
#OralBacteriaBloodstreamTranslocation
#InsulinReceptorDamage
#Epigenetics
November 30, 2024 at 11:28 PM
4k words added to a chapter on #T2DM written today (will need editing).
Simplified summary - diabetes is all about oral biology/health.
#GumDisease
#Periodontitis
#Pgingivalis
#InsulinResitance
#SystemicInflammation
#OralBacteriaBloodstreamTranslocation
#InsulinReceptorDamage
#Epigenetics
Simplified summary - diabetes is all about oral biology/health.
#GumDisease
#Periodontitis
#Pgingivalis
#InsulinResitance
#SystemicInflammation
#OralBacteriaBloodstreamTranslocation
#InsulinReceptorDamage
#Epigenetics
All with #Diabetes (DM) or caring for people with DM need to understand this diagram.
It explains the processes by which #OralDysbiosis (responsible for gum disease) causes DM.
(DM also worsens #GumDisease)
#ViciousCircle
Link to paper👇
bit.ly/4g9bwni
It explains the processes by which #OralDysbiosis (responsible for gum disease) causes DM.
(DM also worsens #GumDisease)
#ViciousCircle
Link to paper👇
bit.ly/4g9bwni
November 28, 2024 at 11:31 AM
All with #Diabetes (DM) or caring for people with DM need to understand this diagram.
It explains the processes by which #OralDysbiosis (responsible for gum disease) causes DM.
(DM also worsens #GumDisease)
#ViciousCircle
Link to paper👇
bit.ly/4g9bwni
It explains the processes by which #OralDysbiosis (responsible for gum disease) causes DM.
(DM also worsens #GumDisease)
#ViciousCircle
Link to paper👇
bit.ly/4g9bwni
Porphyromonas gingivalis is the most pathological microorganism known to humanity.
Prove me wrong…
#OralDysbiosis
#PeriodontalDisease
#Atherosclerosis
#InsulinResistance
#AutoimmuneDisease
#Alzheimers
#GutDysbiosis
#PregnancyComplications
#Cancers
Prove me wrong…
#OralDysbiosis
#PeriodontalDisease
#Atherosclerosis
#InsulinResistance
#AutoimmuneDisease
#Alzheimers
#GutDysbiosis
#PregnancyComplications
#Cancers
November 22, 2024 at 11:32 AM
Porphyromonas gingivalis is the most pathological microorganism known to humanity.
Prove me wrong…
#OralDysbiosis
#PeriodontalDisease
#Atherosclerosis
#InsulinResistance
#AutoimmuneDisease
#Alzheimers
#GutDysbiosis
#PregnancyComplications
#Cancers
Prove me wrong…
#OralDysbiosis
#PeriodontalDisease
#Atherosclerosis
#InsulinResistance
#AutoimmuneDisease
#Alzheimers
#GutDysbiosis
#PregnancyComplications
#Cancers
‘Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects’
Translation:
Toxic enzymes produced by gum disease bacteria cause type 2 diabetes
www.nature.com/articles/s41...
Translation:
Toxic enzymes produced by gum disease bacteria cause type 2 diabetes
www.nature.com/articles/s41...
November 19, 2024 at 5:00 PM
‘Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects’
Translation:
Toxic enzymes produced by gum disease bacteria cause type 2 diabetes
www.nature.com/articles/s41...
Translation:
Toxic enzymes produced by gum disease bacteria cause type 2 diabetes
www.nature.com/articles/s41...
For our failure to understand the importance of oral health and a healthy oral microbiome in determining our whole body health, future generations will pity us and the dark ages in which we live.
#OralHealth
#OralMicrobiome
#CVD
#Diabetes
#Alzheimers
#Rheumatoid
#Cancer
#IBD
#OralHealth
#OralMicrobiome
#CVD
#Diabetes
#Alzheimers
#Rheumatoid
#Cancer
#IBD
November 19, 2024 at 10:30 AM
For our failure to understand the importance of oral health and a healthy oral microbiome in determining our whole body health, future generations will pity us and the dark ages in which we live.
#OralHealth
#OralMicrobiome
#CVD
#Diabetes
#Alzheimers
#Rheumatoid
#Cancer
#IBD
#OralHealth
#OralMicrobiome
#CVD
#Diabetes
#Alzheimers
#Rheumatoid
#Cancer
#IBD
Important discussion on oral health in children with @JamesTGallagher @BBCRadio4
The next step is to understand the links between poor #oralhealth and development of systemic diseases.
Caring for the mouth = caring for the body.
www.bbc.co.uk/sounds/play/...
The next step is to understand the links between poor #oralhealth and development of systemic diseases.
Caring for the mouth = caring for the body.
www.bbc.co.uk/sounds/play/...
Radio 4 - Listen Live - BBC Sounds
Listen live to BBC Radio 4 on BBC Sounds
www.bbc.co.uk
November 19, 2024 at 10:13 AM
Important discussion on oral health in children with @JamesTGallagher @BBCRadio4
The next step is to understand the links between poor #oralhealth and development of systemic diseases.
Caring for the mouth = caring for the body.
www.bbc.co.uk/sounds/play/...
The next step is to understand the links between poor #oralhealth and development of systemic diseases.
Caring for the mouth = caring for the body.
www.bbc.co.uk/sounds/play/...