Anna Roberts
@drannaroberts.bsky.social
Postdoc @ImperialCollege | Neuroendocrinology, metabolism, reproductive & women’s health 🧠👩🏼🔬 | Outdoor enthusiast 🌿 | Views my own
Thank you to the @ox.ac.uk Cortex Club for the chance to discuss the latest @novonordisk.bsky.social EVOKE & EVOKE+ trial updates, and the role we believe GIPR plays in maintaining vascular health 🧠✨
Great discussion and insightful questions 🙏
Manuscript out soon — stay tuned 📄📢
Great discussion and insightful questions 🙏
Manuscript out soon — stay tuned 📄📢
November 26, 2025 at 7:36 PM
Thank you to the @ox.ac.uk Cortex Club for the chance to discuss the latest @novonordisk.bsky.social EVOKE & EVOKE+ trial updates, and the role we believe GIPR plays in maintaining vascular health 🧠✨
Great discussion and insightful questions 🙏
Manuscript out soon — stay tuned 📄📢
Great discussion and insightful questions 🙏
Manuscript out soon — stay tuned 📄📢
Reposted by Anna Roberts
📣 New review out from @trapp-lab.bsky.social!
Read to learn about the physiology and anti-obesity potential of preproglucagon neurons 🧠
Link here:
academic.oup.com/endo/article...
Read to learn about the physiology and anti-obesity potential of preproglucagon neurons 🧠
Link here:
academic.oup.com/endo/article...
Brain-Derived GLP-1—Understanding the Physiological Function and Anti-obesity Potential of Preproglucagon Neurons
Abstract. Glucagon-like peptide-1 (GLP-1) is produced within the central nervous system (CNS) by preproglucagon (PPG) neurons. This brain-derived GLP-1, ra
academic.oup.com
November 25, 2025 at 6:20 AM
📣 New review out from @trapp-lab.bsky.social!
Read to learn about the physiology and anti-obesity potential of preproglucagon neurons 🧠
Link here:
academic.oup.com/endo/article...
Read to learn about the physiology and anti-obesity potential of preproglucagon neurons 🧠
Link here:
academic.oup.com/endo/article...
…and just like that, 2.5 great years come to an end. Huge thanks to everyone in @ccmnlondon.bsky.social for an amazing first postdoc experience & @adriaenssenslab.bsky.social and @nataliefigueredob.bsky.social for making such a great team! Excited for what’s next @imperialmdr.bsky.social 🚀
September 26, 2025 at 7:50 AM
…and just like that, 2.5 great years come to an end. Huge thanks to everyone in @ccmnlondon.bsky.social for an amazing first postdoc experience & @adriaenssenslab.bsky.social and @nataliefigueredob.bsky.social for making such a great team! Excited for what’s next @imperialmdr.bsky.social 🚀
Thanks to @theiups.bsky.social 2025 meeting for a great Vascular Health and Function session where I was pleased to share exciting new data!
Another day, another excellent talk from a @ccmnlondon.bsky.social member. Dr. Anna Robert’s from @adriaenssenslab.bsky.social lab presented her work on GIP and vascular health here at @theiups.bsky.social 2025 meeting in Frankfurt.
September 14, 2025 at 7:45 AM
Thanks to @theiups.bsky.social 2025 meeting for a great Vascular Health and Function session where I was pleased to share exciting new data!
Pleased to share a new paper that I'm proud to have contributed to 🌟 Grateful for the chance to work with such a talented team 🙌
Interested in brain access for Tirzepatide-based drugs? Have a look at the fluorescent Tirzepatide analogue developed by Johannes Broichhagen and David Hodson @daveyboyhod.bsky.social out now in Nature Metabolism www.nature.com/articles/s42.... Proud to contribute to this great multi-lab effort.
Fluorescent GLP1R/GIPR dual agonist probes reveal cell targets in the pancreas and brain - Nature Metabolism
A series of fluorescent probes is designed that act as dual agonists on both GLP1 and GIP receptors, and are used to image receptor binding activities in tissues and animals.
www.nature.com
August 19, 2025 at 2:32 PM
Pleased to share a new paper that I'm proud to have contributed to 🌟 Grateful for the chance to work with such a talented team 🙌
Really enjoyed working on this - big thanks to everyone involved!
Online now: Glucose-dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight-loss action of GLP-1R agonism
Glucose-dependent insulinotropic polypeptide receptor signaling in oligodendrocytes increases the weight-loss action of GLP-1R agonism
Hansford et al. show that GIPR, a target of new weight-loss drugs, is found in brain cells called oligodendrocytes. GIPR helps these drugs access the brain and boosts weight loss. Without GIPR in these cells, the drugs are less effective, revealing a new mechanism behind their action.
dlvr.it
August 14, 2025 at 10:36 AM
Really enjoyed working on this - big thanks to everyone involved!
A big congratulations to @nataliefigueredob.bsky.social 🥳
Unbelievably proud of @nataliefigueredob.bsky.social for winning the prestigious Bogue Fellowship 🌟 She'll be heading across the pond to train with the @zknight.bsky.social lab for 3 months. Exciting things to come for this bright young scientist 🧠. @uclnpp.bsky.social @ccmnlondon.bsky.social
June 24, 2025 at 1:01 PM
A big congratulations to @nataliefigueredob.bsky.social 🥳
Excited to share a new preprint from work I did during my PhD! 🎉
Here we uncover a direct gut-pancreas neuronal circuit that drives the glucoregulatory response to lipids 🫒
Huge thanks to @imperialcollegeldn.bsky.social and all involved.
Read it here 📄:
www.biorxiv.org/content/10.1...
Here we uncover a direct gut-pancreas neuronal circuit that drives the glucoregulatory response to lipids 🫒
Huge thanks to @imperialcollegeldn.bsky.social and all involved.
Read it here 📄:
www.biorxiv.org/content/10.1...
www.biorxiv.org
May 20, 2025 at 12:04 PM
Excited to share a new preprint from work I did during my PhD! 🎉
Here we uncover a direct gut-pancreas neuronal circuit that drives the glucoregulatory response to lipids 🫒
Huge thanks to @imperialcollegeldn.bsky.social and all involved.
Read it here 📄:
www.biorxiv.org/content/10.1...
Here we uncover a direct gut-pancreas neuronal circuit that drives the glucoregulatory response to lipids 🫒
Huge thanks to @imperialcollegeldn.bsky.social and all involved.
Read it here 📄:
www.biorxiv.org/content/10.1...
Reposted by Anna Roberts
It's a big week for GIPR pharmacology! Two great studies out in @natmetabolism.nature.com from Gutgesell et al (www.nature.com/articles/s42...) and Liu et al (www.nature.com/articles/s42...) revealing divergent neural mechanisms engaged by GIPR agonism vs antagonism. Commentary here: rdcu.be/ejPSA
GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice - Nature Metabolism
This study, together with a companion manuscript, show that, in mice, weight loss as a result of GIP receptor antagonism requires, and potentiates, functional GLP-1 receptor signalling in the brain, e...
www.nature.com
April 29, 2025 at 1:20 PM
It's a big week for GIPR pharmacology! Two great studies out in @natmetabolism.nature.com from Gutgesell et al (www.nature.com/articles/s42...) and Liu et al (www.nature.com/articles/s42...) revealing divergent neural mechanisms engaged by GIPR agonism vs antagonism. Commentary here: rdcu.be/ejPSA
Reposted by Anna Roberts
📣Join the Trapp lab as a Postdoctoral Research Fellow!
The Trapp lab is seeking for a highly motivated Research Fellow to explore the role of GLP-1 action within the brain. If you are interested we encourage you to apply!
📍 Location: UCL, London
📆 Application deadline: March 19th
The Trapp lab is seeking for a highly motivated Research Fellow to explore the role of GLP-1 action within the brain. If you are interested we encourage you to apply!
📍 Location: UCL, London
📆 Application deadline: March 19th
March 7, 2025 at 9:00 AM
📣Join the Trapp lab as a Postdoctoral Research Fellow!
The Trapp lab is seeking for a highly motivated Research Fellow to explore the role of GLP-1 action within the brain. If you are interested we encourage you to apply!
📍 Location: UCL, London
📆 Application deadline: March 19th
The Trapp lab is seeking for a highly motivated Research Fellow to explore the role of GLP-1 action within the brain. If you are interested we encourage you to apply!
📍 Location: UCL, London
📆 Application deadline: March 19th
Reposted by Anna Roberts
Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
GLP-1 and the Neurobiology of Eating Control: Recent Advances
Abstract. Obesity is now considered a chronic relapsing progressive disease, associated with increased all-cause mortality that scales with body weight, af
academic.oup.com
January 21, 2025 at 11:59 AM
Really proud to start the year by sharing our new review in @endosocjournals.bsky.social on the roles of GLP-1 in eating and obesity treatment, led by superstar postdoc @laurenjonesucl.bsky.social!
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
academic.oup.com/endo/article...
🧪🧠📈 #neuroscience #neuroskyence #GLP-1 #obesity #wegovy #ozempic
Reposted by Anna Roberts
📣 We are excited to launch this year’s CCMN Lecture Series with Dr. @zknight.bsky.social! Join us to learn about his latest work on:
In vivo imaging of brainstem neurons in response to nutrient intake.
🗓️ Wednesday, Dec 4, 2024
🕐 13:00
📍 H O Schild Lecture Theatre, Medical Sciences Building
In vivo imaging of brainstem neurons in response to nutrient intake.
🗓️ Wednesday, Dec 4, 2024
🕐 13:00
📍 H O Schild Lecture Theatre, Medical Sciences Building
December 2, 2024 at 8:54 PM
📣 We are excited to launch this year’s CCMN Lecture Series with Dr. @zknight.bsky.social! Join us to learn about his latest work on:
In vivo imaging of brainstem neurons in response to nutrient intake.
🗓️ Wednesday, Dec 4, 2024
🕐 13:00
📍 H O Schild Lecture Theatre, Medical Sciences Building
In vivo imaging of brainstem neurons in response to nutrient intake.
🗓️ Wednesday, Dec 4, 2024
🕐 13:00
📍 H O Schild Lecture Theatre, Medical Sciences Building