CVCT Forum
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A Forum for #CardioVascular Clinical Trialists. Best update on the latest clinical trials of the year! https://www.globalcvctforum.com/ 22nd CVCT Forum | December 8-10, 2025
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Sessions will highlight practical IND strategies and frameworks for safety monitoring developed by leading teams. Experts will also discuss emerging models for ensuring safety, access, and reimbursement.
Join us, December 8-10, Washington DC! www.globalcvctforum.com/scientific-p...
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
#CVCT2025: How can gene therapy be effectively implemented in rare and complex cardiovascular conditions? This section addresses patient selection, the design of adaptive clinical trials, and regulatory pathways tailored for orphan populations.
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Don’t miss your chance to share your work and be part of the global discussion shaping the future of cardiovascular clinical research!
cvctforum.bsky.social
For simultaneous full manuscript publication in JACC, please contact directly [email protected] for additional information.
For any additional questions, please contact us at [email protected]
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We’re excited to share an important update:
1. Abstract Submissions – New Deadline: October 20, 2025
We are now accepting abstracts from both industry and academic contributors.
👉Find the guidelines and the submission link here: : www.globalcvctforum.com/poster-prese...
cvctforum.bsky.social
This session will include highly anticipated debates on the role and feasibility of placebo-controlled device trials as well as on the optimal approach to analysis and reporting of health status and quality of life endpoints.
Join us, Dec 8-10, Washington DC: www.globalcvctforum.com/scientific-p...
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
#iCVCT2025: At iCVCT, there will be a unique menu of sessions covering clinical trial design and regulatory considerations for cardiovascular devices. I am particularly excited about the session on Controversies in Clinical Trial Design for Structural Heart Interventions.
cvctforum.bsky.social
CVCT meeting attract global leaders representing all aspects of clinical trials including trialists, clinicians, sponsors, regulators, funders, payers, editors, and patients and advocacy groups. Your research results will find a broad expert audience.
Late Breaking Clinical Trial Submissions at CVCT 2025 | Global CVCT Forum
The CVCT Meeting is excited to announce a new feature this year: an invitation for Late-Breaking Clinical Trial Submissions! This is your chance to present impactful, cutting-edge clinical trial resul...
www.globalcvctforum.com
cvctforum.bsky.social
#CVCT2025: This year, you have the opportunity to share impactful, cutting-edge results on a global stage and to contribute to shaping the future of innovative therapies and clinical trial science.
cvctforum.bsky.social
and attempts to trigger a true myocardial regeneration by a mRNA-based activation of endogenous pathways involved in cardiomyocyte cycling and division.

Discover our scientific program and join us, December 8-10, 2025, Washingto, DC: www.globalcvctforum.com/scientific-p...
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
reassessment of delivery routes and dosing strategies taking into account the role of the immune landscape as a key driver of heart failure and aimed at streamlining the implementation of both cell-based and secretome-based strategies;
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
transplantation of cardiomyocytes differentiated from pluripotent stem cells to induce remuscularization of the chronically failing heart; switch towards the exclusive use of the cellular secretome shown to duplicate the cardio-protective effects of the parental cells;
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
#CVCT2025: Even though outcomes of the early cell therapy trials have not matched the expectations, the concept of leveraging the bioactivity of cells for improving cardiac function in heart failure is still under active development and research now spans the main following areas:
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Those countermeasures and their impact on clinical strategies, timelines, and availability of key medical devices will be discussed during this session. Both the EU and the US will be compared by looking to the pros and cons of both regions with regard to regulatory approval processes.
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
The Union Market (EU) is undergoing legislative changes since 2017 which impacted the attractiveness of this market and today, we started seeing political countermeasures to reestablish a patient-oriented healthcare system.
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
#CVCT2025: The Think Tank we have assembled around Clinical Trial on Breakthrough devices in the US and the EU will discuss the undergoing changes in the EU and the US and their impact on the holistic regulatory and clinical strategies and timelines.
cvctforum.bsky.social
inhalation as a new route of drug administration, mortality and its surrogates as end points and the recent decisions to terminate RCTs on the basis of efficacy, safety or futility. Discover the program and join us December 8-10, 2025, Washington DC: www.globalcvctforum.com/scientific-p...
#CVCT
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com
cvctforum.bsky.social
#CVCT2025: THE FUTURE OF PULMONARY HYPERTENSION TRIALS. Pulmonary arterial hypertension is a severe but treatable disease which has benefited from substantial advances in CT designs and drug development. We'll discuss RCT design in patients treated with approved agents targeting four pathways,
cvctforum.bsky.social
The Think Tank we have assembled around #cardiacamyloidosis trials will explore prevention, precision, and combination strategies. With leading voices from academia, regulators, industry, and patients, we’ll tackle trial design for early disease, AI-based screening, and endpoints that matter.
cvctforum.bsky.social
Sessions will focus on IND-enabling studies, challenges related to seroprevalence, and strategies currently used in clinical trials; discussion of immune-related lethal adverse events and approaches to mitigate these risks. Insights will be shared by field leaders & FDA stakeholders.
CVCT Global Forum Scientific Program 2025
Discover the unique high science & discussion program for CVCT 2025 (Global CardioVascular Trialists Forum), December 8-10, at the Mayflower Hotel, Washington DC
www.globalcvctforum.com