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Contagion® @contagionlive.bsky.social · 22h

Cefiderocol is noninferior to standard of care empiric treatment of noscomial Gram-negative bloodstream infections in open-label "Game-Changer" trial. #IDsky #Medsky

Cefiderocol is Noninferior, But not "Game-Changer," for Gram-negative Bloodstream Infections | Contagion Live

Cefiderocol is noninferior to standard of care empiric treatment of noscomial Gram-negative bloodstream infections in open-label "Game-Changer" trial.

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Contagion® @contagionlive.bsky.social · 1d

This week, learn about the Center for Discovery and Innovation's research around antivirals, the hepatitis C bill in Congress, how AI is influencing antimicrobial development, and more. #IDsky #Medsky

Top Infectious Disease News Stories Week of October 3-October 10 | Contagion Live

This week, learn about the Center for Discovery and Innovation's research around antivirals and antifungals, the hepatitis C bill in Congress, how AI is influencing antimicrobial development, and mor...

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Contagion® @contagionlive.bsky.social · 2d

Barry Kreiswirth, PhD, discusses this emerging challenge that is ongoing in both the community and healthcare settings, especially around resistant urinary tract infections and how this type of resistance can grow exponentially across strain and pathogens. #IDsky

Uncovering the Challenges of Multidrug-Resistant Klebsiella Infections | Contagion Live

The Center for Discovery and Innovation’s Barry Kreiswirth, PhD, discusses this emerging challenge that is ongoing in both the community and healthcare settings, especially around resistant urinary tr...

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Contagion® @contagionlive.bsky.social · 2d

AI predicted mechanism of action for investigational, narrow spectrum antibiotic against pathogens in Crohn's disease and IBD-related conditions. #IDsky #Medsky

AI Predicts Mechanism of Investigational Antibiotic for Crohn's Disease

AI predicted mechanism of action for investigational, narrow spectrum antibiotic against pathogens in Crohn's disease and IBD-related conditions.

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Contagion® @contagionlive.bsky.social · 3d

David Perlin, PhD, chief scientific officer and executive vice president, the Center for Discovery and Innovation (CDI), talks about his team’s work around developing a diagnostic for Candida auris, and what they are working on in terms of developing antifungals. #IDsky #Medsky

The Center for Discovery and Innovation’s Commitment to Fungal Diagnostics and Treatment

David Perlin, PhD, chief scientific officer and executive vice president, the Center for Discovery and Innovation (CDI), talks about his team’s work around developing a diagnostic for Candida auris, a...

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Contagion® @contagionlive.bsky.social · 3d

The company is advancing R327G, a novel synthetic anti-infective for diabetic foot infections, through a phase 3 clinical trial in Indonesia, marking a step toward the first new anti-infective class approval in over 40 years. #IDsky #Medsky

Recce Pharmaceuticals Targets Diabetic Foot Infections With First-in-Class Synthetic Anti-Infective

The company is advancing R327G, a novel synthetic anti-infective for diabetic foot infections, through a phase 3 clinical trial in Indonesia, marking a major step toward the first new anti-infective c...

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Contagion® @contagionlive.bsky.social · 4d

In our continuing Media Day series, the Center for Discovery and Innovation’s Chief Scientific Officer David Perlin, PhD, discusses the factors for the growing number of cases, and the difficulties in developing such treatments. #IDsky #Medsky

A Limited Antifungal Market is Treating an Increasing Number of Fungal Infections

The Center for Discovery and Innovation’s Chief Scientific Officer David Perlin, PhD, discusses the factors for the growing number of cases, and the difficulties in developing such treatments.

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Contagion® @contagionlive.bsky.social · 4d

The act aims to expand testing, treatment, and prevention through a subscription-based model. The legislation would invest billions in public health infrastructure, remove barriers to curative therapies, and ensure high-risk and underserved populations have access to life-saving HCV treatment.

Cure Hepatitis C Act 2025: US Strategy to End Hepatitis C

Through the bipartisan Cure Hepatitis C Act of 2025, legislation seeks to provide nationwide hepatitis C treatment and strengthen public health infrastructure by expanding testing, treatment, and prev...

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Contagion® @contagionlive.bsky.social · 5d

The center’s Chief Scientific Officer David Perlin, PhD, provides some insights on the evolution of their antiviral program from its foundation in treating COVID-19 to addressing all pancoronaviruses. #IDsky #Medsky

The Center for Discovery and Innovation: Harnessing the Cutting Edge of Medical Science

The center’s Chief Scientific Officer David Perlin, PhD, provides some insights on the evolution of their antiviral program from its foundation in treating COVID-19 to addressing all pancoronaviruses.

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Contagion® @contagionlive.bsky.social · 5d

Your liver silently powers and protects your body every day, but untreated hepatitis infections, excessive alcohol, and poor diet can destroy its vital cells, leading to fatigue, cirrhosis, and liver cancer if not prevented through awareness and care.

Hepatitis and Cancer: Silent Threats to the Liver

Your liver silently powers and protects your body every day, but untreated hepatitis infections, excessive alcohol, and poor diet can destroy its vital cells, leading to fatigue, cirrhosis, and liver ...

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Contagion® @contagionlive.bsky.social · 5d

George Sakoulas, MD, discusses how antimicrobial selection for patients with pneumonia depends on illness severity, seasonal pathogen patterns, comorbidities, and prior antibiotic exposure, with particular attention to high-risk populations requiring tailored therapy.

Tailoring Pneumonia Treatment: How Severity, Season, and Comorbidities Guide Antimicrobial Choices

An expert discusses how antimicrobial selection for patients with pneumonia depends on illness severity, seasonal pathogen patterns, comorbidities, and prior antibiotic exposure, with particular atten...

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Contagion® @contagionlive.bsky.social · 6d

The US Department of Agriculture’s Food Safety and Inspection Service (FSIS) provides information on the 2 companies recalls and the products.

Corndog, Sausage on a Stick Recalls

The US Department of Agriculture’s Food Safety and Inspection Service (FSIS) provides information on the 2 companies recalls and the products.

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Contagion® @contagionlive.bsky.social · 6d

William Schaffner MD, provides more context around the committee’s vaccines recommendations. #IDsky #Medsky

Further Insights Around the ACIP’s Recent Series of Meetings

William Schaffner MD, provides more context around the committee’s vaccines recommendations.

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Contagion® @contagionlive.bsky.social · 7d

S aureus bloodstream infections, particularly those caused by MRSA, remain a major cause of morbidity and mortality, underscoring the need for novel, broad-spectrum treatments like ceftobiprole that can address both resistant and susceptible strains. #IDsky #Medsky

Staphylococcus aureus Bloodstream Infections: Persistent Challenges and Emerging Therapeutic Opportunities

Despite modest progress, Staphylococcus aureus bloodstream infections—particularly those caused by MRSA—remain a major cause of morbidity and mortality, underscoring the urgent need for novel, broad-s...

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Contagion® @contagionlive.bsky.social · 8d

This week: C diff and hepatitis roundups, how COVID-19 has disrupted traditional respiratory virus patterns, a review of a trial comparing dalbavancin with standard intravenous therapy for Staphylococcus aureus, and more.

Top Infectious Disease News Stories Week of September 27-October 3

This week, there are C diff and hepatitis roundup reports, how COVID-19 has disrupted traditional respiratory virus patterns with summer surges now preceding the typical winter influenza season, a re...

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Contagion® @contagionlive.bsky.social · 9d

University of Oregon researchers found that adding a common chemical, chlorate, to standard antibiotics made them up to 10,000 times more effective in lab tests against hard-to-treat bacteria, offering a potential breakthrough for chronic wound care.

Chemical Compound Supercharges Antibiotics to Fight Chronic Wound Infections

University of Oregon researchers found that adding a common chemical, chlorate, to standard antibiotics made them up to 10,000 times more effective in lab tests against hard-to-treat bacteria, offerin...

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Contagion® @contagionlive.bsky.social · 9d

TAXIS Pharmaceuticals Chief Scientific Officer Ajit Parhi, PhD, offers some insights on NDM-CRE, antimicrobial resistance, and an overview of his company’s pipeline. #IDsky #Medsky

Addressing Resistance to Pathogens Like NDM-CRE Through the Lens of Antimicrobial Development

Infections caused by NDM-producing carbapenem-resistant Enterobacterales have risen more than fourfold since 2019, raising alarms about limited treatment options, delayed detection, and heightened ris...

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Contagion® @contagionlive.bsky.social · 10d

Recce Pharmaceuticals has begun its study for this indication in Indonesia with its investigational product, RECCE 327 topical gel. #IDsky #Medsky

Phase 3 Trial Begins for Topical Gel for Diabetic Foot Infections

Recce Pharmaceuticals has begun its study for this indication in Indonesia with its investigational product, RECCE 327 topical gel (R327G).

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Contagion® @contagionlive.bsky.social · 10d

Stewardship programs that reduce initial use of extended-spectrum antibiotics appear to influence antibiotic choice throughout hospitalization. #IDsky #Medsky

Guidance on Initial Antibiotic Influences Subsequent Prescribing

Stewardship programs that reduce initial use of extended-spectrum antibiotics appear to influence antibiotic choice throughout hospitalization.

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Contagion® @contagionlive.bsky.social · 10d

Today is #WorldMRSADay! In a previous interview, Jeanine Thomas, president and founder of MRSA Survivors Network, talks about her personal with it, her work as an advocate, and the need for data and awareness to bring it to the forefront again.

Bringing MRSA Back to the Forefront

Jeanine Thomas, president and founder of MRSA Survivors Network, talks about her personal battle with osteomyelitis, her work as an advocate, and the need for data and awareness to bring it to the for...

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Contagion® @contagionlive.bsky.social · 11d

The Centers for Disease Control and Prevention (CDC) provided more information on a multistate outbreak and genomic testing. #IDsky #Medsky

Listeria Outbreak Update: 3 More Illnesses and 1 Death Linked to Packaged Meals

The Centers for Disease Control and Prevention (CDC) provided more information on a multistate outbreak and genomic testing.

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Matt Hoffman @bymatthoffman.bsky.social · 11d

A lot happened last month in the @cdcgov.govmirrors.com's latest ACIP vaccines meeting. Amid the debate, though, there was clinically relevant conversation. @contagionlive.bsky.social was on the case with coverage, and I did my best to summarize some of that here:
www.linkedin.com/pulse/naviga...

Navigating Clarity in a Cloudy Vaccine Landscape: ACIP’s September 2025 Decisions and What They Mean for Clinical Practice

In what perhaps came as no surprise, this month’s Centers for Disease Control and Prevention Advisory Committee on Immunization Practices (ACIP) meeting—taking place over the 2-day span of September 1...

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Contagion® @contagionlive.bsky.social · 11d

Low vaccination rates did not rise sufficiently to attain "herd immunity" after a measles outbreak in a region in which it had been eliminated. #IDsky #Medsky

Vaccination Rates Remain Low after Measles Outbreak

Low vaccination rates did not rise sufficiently to attain "herd immunity" after a measles outbreak in a region in which it had been eliminated.

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Contagion® @contagionlive.bsky.social · 11d

A multicenter study will measure efficacy, safety, and immunogenicity in adults 18–59 across Europe. #IDsky #Medsky

Osivax Launches Phase 2b Study of OVX836 for Influenza A

Multicenter study will measure efficacy, safety, and immunogenicity in adults 18–59 across Europe.

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Contagion® @contagionlive.bsky.social · 11d

We launched a new, short series on the DOTS trial, which compared dalbavancin with standard intravenous therapy for the completion of treatment in adults with complicated Staphylococcus aureus. #IDsky #Medsky

Two-Dose Antibiotic Regimen Offers Safer Alternative to Prolonged IV Therapy in Complicated Staph Aureus Infections

Contagion® is a news resource for infectious disease specialists and practitioners, aiding identification, diagnosis, treatment and prevention.

www.contagionlive.com

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