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Josep Clotet

@clotetlab.bsky.social

4 followers 9 following 3 posts

Playing with Atypical Cyclins and polyPhosphate in Barcelona

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Reposted by Josep Clotet

bioRxivpreprint @biorxivpreprint.bsky.social · May 2

Amyloid Accelerator Polyphosphate Implicated as the Mystery Density in α-Synuclein Fibrils https://www.biorxiv.org/content/10.1101/2024.05.01.592011v1

Aberrant aggregation of -Synuclein is the pathological hallmark of a set of neurodegenerative diseas

www.biorxiv.org

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Reposted by Josep Clotet

UCL Discovery @ucldiscovery.bsky.social · Apr 8

Open Access UCL Research: Human plasma inositol hexakisphosphate (InsP 6 ) phosphatase identified as the Multiple Inositol Polyphosphate Phosphatase 1 (MINPP1) discovery.ucl.ac.uk/id/eprint/10...

discovery.ucl.ac.uk

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Reposted by Josep Clotet

Cameron Thrash @jcamthrash.bsky.social · Feb 19

Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure onlinelibrary.wiley.com/doi/10.1111/... #jcampubs

Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure

Polyphosphate condensates and their contributions to nucleoid structure. Polyphosphate condensates form in the ribosome-depleted nucleoid region of bacterial cells, particularly under stress (in this...

onlinelibrary.wiley.com

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Josep Clotet @clotetlab.bsky.social · Jan 7

This new protocol achieves up to 100x more efficiency than some previous techniques. 🚀🔬
#polyphosphate
#biochemistry

Josep Clotet @clotetlab.bsky.social · Jan 7

Proud to share our latest work with @jessenlab.bsky.social !
We optimized a method to purify polyphosphate in human cells.

The paper reviews critical steps in protocols, shares physiological insights, and yes – we’ve got NMR snapshots of mammalian polyP!
Read more: doi.org/10.1016/j.ym...
#polyP

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Josep Clotet @clotetlab.bsky.social · Nov 17

Helllow world.
I'm almost ready to leave X and start our conversation here.
See you soon