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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

The North American Congress of Clinical Toxicology 2025 abstracts are here! Which ones are your favorites?

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North American Congress of Clinical Toxicology (NACCT) 2025

Published in Clinical Toxicology (Vol. 63, No. sup3, 2025)

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this retrospective review of cases where patients received flumazenil, seizures occurred in only a small amount (2.6%) of patients

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this retrospective review of 50,323 unintentional mushroom exposures in children ≤5 years, major outcomes were quite rare

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this retrospective study of 64 cases of adverse effects from consumed liquorice, liquorice-related effects were found to be rare but had high severity.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

A study of French poison control centers found that their standardized poisoning causality method for poisoning had moderate inter-rater reliability (κ = 0.55) and good sensitivity

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Evaluation of the reproducibility and validity of the use of the causality assessment method for poisonings designed and applied by the French poison control centres

French poison control centres have developed and use a standardised causality assessment method based on a decision tree for poisoning cases involving a wide range of xenobiotics, which includes fi...

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this study of nearly 31,000 pediatric single-substance exposures associated with seizures, cases nearly doubled from 2009 to 2023. The major contributors to this were diphenhydramine and bupropion.
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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this 25-year retrospective review of 41 amlodipine overdose cases, patients with ingestions ≥400 mg were at high risk for refractory shock.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this retrospective study of emergency department encounters, droperidol use in patients with cannabinoid hyperemesis syndrome was associated with shorter length of stay, decreased total medication needs, and less opioid use.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this retrospective study, rising recreational ketamine use was paralleled by a rise in ketamine-induced uropathy, with some patients even requiring surgery.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this retrospective study of 276 children with poisoning-related neurological features, altered consciousness was the most commonly reported symptom. Non-neurological factors such as suicidal intent were found to be important in hospitalization decisions.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 16

In this case series of 275 patients presenting to clinical toxicology units, seizures were most common after tramadol, 3,4-methylenedioxymetamfetamine, quetiapine and cocaine. Seizure recurrence happened in 20% of patients.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

An infant born to a mother who reported polysubstance use, including heavy use of nitrous oxide, exhibited white matter hyperdensities and significant developmental delay www.tandfonline.com/doi/full/10....

Intrauterine exposure to nitrous oxide and neurological sequelae in an infant

Published in Clinical Toxicology (Vol. 63, No. 7, 2025)

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

An infant born to a mother who reported polysubstance use, including heavy use of nitrous oxide, exhibited white matter hyperdensities and significant developmental delay www.tandfonline.com/doi/full/10....

Intrauterine exposure to nitrous oxide and neurological sequelae in an infant

Published in Clinical Toxicology (Vol. 63, No. 7, 2025)

www.tandfonline.com

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

Report: Unregulated street vendors in New York City are selling packages containing 80% zinc phosphide www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

A 91-year-old woman developed laryngeal edema after ingestion of the ornamental plant Alocasia odora www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

A modified apelin peptide prevented bupivacaine-induced cardiac toxicity in a rat model www.tandfonline.com/doi/full/10....

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

A micro-signal analysis method may help detect hidden trends in poison center data www.tandfonline.com/doi/full/10....

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Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

A 20-year study of benzonatate exposures found that while intentional exposures often have severe outcomes (including death in 2 of 106 instances), unintentional exposures rarely exhibit serious toxicity. www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

Derivation and internal validation of the Clinical Aconite Poisoning Score (CAPS), intended to facilitate early recognition of aconite poisoning www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

Calls to California poison centers regarding water bead exposures have increased dramatically over the past 10 years. Few cases required procedural intervention. www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

In this series of 110 patients, anaphylactoid reactions to IV acetylcysteine were much more common after wild mushroom poisoning than after acetaminophen poisoning www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Sep 8

Of 632 pharmacobezoar-related reports in VigiBase, most were serious and necessitated hospitalization. Levodopa-carbidopa and psychotropic drugs were often implicated. www.tandfonline.com/doi/full/10....

Clinical Toxicology @clinicaltoxicology.bsky.social · Jul 10

A 20-year-old farmer self-injected a veterinary product containing calcium copper edetate and developed hemolysis, acute kidney injury, and rhabdomyolysis. The patient was treated with dialysis, penicillamine, and plasma exchange.

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Clinical Toxicology @clinicaltoxicology.bsky.social · Jul 10

In this case series, two patients ingested 10 g of elemental arsenic without developing toxicity (one patient received succimer for 3 days, the other patient received gastric lavage and whole bowel irrigation).

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Clinical Toxicology @clinicaltoxicology.bsky.social · Jul 10

In this retrospective case series, medetomidine was identified as an opioid adulterant associated with patients having sinus bradycardia and requiring prolonged monitoring.

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