Bryony Leeke
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bryonyleeke.bsky.social
Bryony Leeke
@bryonyleeke.bsky.social
Postdoc in the Percharde lab at the MRC LMS studying epigenetics and development.
Kiwi in London.
Gardener, swimmer, v. amateur birdwatcher.
Join @mpercharde.bsky.social Lab at the MRC LMS! We have an 18mo postdoc position to cover a couple of projects (maternity leave and paper revisions). The projects are focussed on chromatin in early mouse embryos and metabolism in mouse embryonic stem cells and pluripotency.
November 27, 2025 at 2:18 PM
Reposted by Bryony Leeke
1/ I’m very excited to share my postdoc work with @kseskv.bsky.social, in collaboration with @oligriffith.bsky.social. We explore embryonic DNA methylation reprogramming in the fat-tailed dunnart, an Australian marsupial 🦘🌏 www.biorxiv.org/content/10.1...
www.biorxiv.org
November 12, 2025 at 2:57 AM
Reposted by Bryony Leeke
#JobAlert! We have an opening for a postdoctoral scientist in #CancerMetabolism in my lab @mrc-lms.bsky.social. If you're interested in the role of metabolism in drug response and resistance in cancer, and would like to work in a fun and friendly team, check it out: lms.mrc.ac.uk/work/vacanci...
MRC Postdoctoral Research Scientist - MRC Laboratory of Medical Sciences
The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...
lms.mrc.ac.uk
June 25, 2025 at 8:57 AM
Reposted by Bryony Leeke
The Chromatin And Development lab are hiring a postdoc!

Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT!

lms.mrc.ac.uk/work/vacanci...
MRC Postdoctoral Research Scientist - MRC Laboratory of Medical Sciences
The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...
lms.mrc.ac.uk
June 26, 2025 at 3:19 PM
Reposted by Bryony Leeke
Issue 9 is complete!

Cover: Neuronal connections in control (left) and Klp61F neuronal knockdown (right) Drosophila larval brains, labelled with photoconvertible EOS-tagged tubulin. Spectrum color-coded hyperstacks of z-stack images show relative spatial positions of neurons doi.org/10.1242/dev....
May 16, 2025 at 1:31 PM
Reposted by Bryony Leeke
In this Review, @bryonyleeke.bsky.social, Imke Staffhorst and @mpercharde.bsky.social @mrc-lms.bsky.social explore roles of the nucleolus in mammalian development, focusing on genome organisation and chromatin regulation:
doi.org/10.1242/dev....
May 16, 2025 at 8:51 AM
Reposted by Bryony Leeke
The nucleolus....large, rather boring organelle in the nucleus? No! Our review led by @bryonyleeke.bsky.social just out @dev-journal.bsky.social, highlighting new findings on nucleoli dynamics in development, intriguing roles in chromatin organisation & more.

journals.biologists.com/dev/article/...
May 14, 2025 at 3:29 PM
Reposted by Bryony Leeke
We're excited to publish our latest study led by Bryony Leeke @bryonyleeke.bsky.social and Wazeer Varsally, now out in @nature.com 🍾This study focusses on the epigenome of marsupial embryos 🦘 mapping DNA methylation in embryo development to specific embryo events www.nature.com/articles/s41... 🧵
Divergent DNA methylation dynamics in marsupial and eutherian embryos - Nature
A study reports on the DNA methylation dynamics during embryogenesis in marsupials, showing that these differ from those occurring during embryogenesis in eutherian mammals.
www.nature.com
May 14, 2025 at 4:01 PM
Reposted by Bryony Leeke
We thrilled to see our latest study led by @jeremie-subrini.bsky.social now out in @science.org 🔬

What are the specific functions of each Y-chromosome gene in fertility ? We generated and studied 13 Y-gene KO mouse models to find out! 🧬

www.science.org/doi/full/10....
www.science.org
January 24, 2025 at 11:02 AM
Reposted by Bryony Leeke
❗ANNOUNCEMENT❗
YEN 2025 Conference will be held at @crick.ac.uk on the 19th May 2025.

We are looking forward to another exciting line-up with Nicolas Rivron, Maud Borensztein and Peter Rugg-Gunn.

This year will see a return of the YEN Image Competition so follow for updates.

Share for #YEN2025!
December 16, 2024 at 12:16 PM