Author | Lightnews

Bernhard Zdársky

@bernhardzdarsky.bsky.social

200 followers 510 following 3 posts

Scientist | Molecular Biologist | Antifascist #Cancer #Metastasis #Leukemia #AML #STAT3 @stoiberlab.bsky.social

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Bernhard Zdársky @bernhardzdarsky.bsky.social · 21d

‼️Our latest study, “Loss of STAT3 in acute myeloid leukemia favors tissue infiltration linked to CXCR4 signaling,” is now out in @bloodneoplasia.bsky.social

#AML #STAT3 #CXCR4 #MLL-AF9
www.sciencedirect.com/science/arti...

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Reposted by Bernhard Zdársky

Gruppe für organisierten Antifaschismus [wien] @gfoa-w.bsky.social · 1d

NAZI-LOKALE AUS DER DECKUNG HOLEN!

Am 6.11. soll in der Weinbar Vino in der Lichtenfelsgasse 3 im 1. Bezirk ein Nazi-Treffen der IB-Tarngruppe "Aktion 451" stattfinden. Dies wollen wir zum Anlass nehmen, das Lokal und dessen Betreiber Heinz Pollischansky näher zu beleuchten.

Eine Grafik mit der Überschrift "Nazi-Lokale aus der Deckung holen! Weinbar Vino, Centimeter & Co"
Darunter zu sehen sind die Logos vom Vino, Centimeter, vom Falco's und der Stiegl Ambulanz. Der Hintergund ist hellblau.

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Reposted by Bernhard Zdársky

Die Mutmacherei @mutmacherei.bsky.social · Sep 19

Bücherfreund:innen aufgepasst! In Wien-Penzing entsteht das BuchQuartier, ein genossenschaftliches Buchcafé. Info-Veranstaltung am 23.9.2025. Mehr dazu hier:
#SDG3 #SDG4 #SDG11 #SDG17 #GLG

Bücherwürmer gesucht!

Bücherfreund:innen aufgepasst! In Wien-Penzing entsteht das BuchQuartier, ein genossenschaftliches Buchcafé. Infoveranstaltung am 23.9.2025. Mehr dazu hier:

mutmacherei.net

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Bernhard Zdársky @bernhardzdarsky.bsky.social · 6d

New research from D’Amico et al. shows that even when KRAS is removed from cancer cells, STAT3 continues to sustain tumorigenicity. This highlights STAT3 as a key vulnerability in KRAS-driven cancers
#KRAS #STAT3

www.embopress.org/doi/full/10....

STAT3 sustains tumorigenicity following mutant KRAS ablation | EMBO reports

imageimageMechanisms underpinning resistance of tumorigenic cells to inactivation of oncogenic KRAS remain to be fully understood. This study shows that STAT3 sustains tumorigenicity of pancreatic cancer cells depleted of the mutant KRAS driver. ...

www.embopress.org

Reposted by Bernhard Zdársky

Blood Journals' Portfolio @bloodjournals.hematology.org · 9d

Patient-specific enhancers in genetically uniform leukemias buff.ly/wU28vLW #hemesky

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Reposted by Bernhard Zdársky

Jeroen Guikema @jeroenguikema.bsky.social · May 4

This aligns with findings from our lab where we show that AKT inhibition synergizes with MCL-1 inhibition to induce cell death in myeloma cells. ashpublications.org/bloodadvance...

AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

Key Points. FOXO transcription factors and the GSK3 kinase are pivotal tumor suppressors restrained by AKT activity in MM cells.FOXO and GSK3 destabilize M

ashpublications.org

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Bernhard Zdársky @bernhardzdarsky.bsky.social · 14d

🔥Interestingly, loss of myeloid STAT3 attenuated steatosis but aggravated inflammation and fibrosis
www.mdpi.com/2073-4409/14...

#Liver #STAT3 #Fibrosis

www.mdpi.com

Reposted by Bernhard Zdársky

TEAM SCHEISSE @teamscheisse.bsky.social · 20d

fanmade sticker🖤🌈

sticker, auf dem steht:
bist du antiantifa, bist du fa

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Bernhard Zdársky @bernhardzdarsky.bsky.social · 21d

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Reposted by Bernhard Zdársky

Nature @nature.com · 29d

Nature research paper: Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22

go.nature.com/4gPjgfA

Dietary cysteine enhances intestinal stemness via CD8+ T cell-derived IL-22 - Nature

Dietary cysteine enhances intestinal stem cell-mediated intestinal repair following injury by promoting CD8 T cell-regenerative immune responses.

go.nature.com

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Reposted by Bernhard Zdársky

Juliane Winkler @jwinkler.bsky.social · Jun 2

Genomics fellows - ever wondered what to do with histopathology (e.g. H&E slides)? 🔬➕🧬🟰🤩 I am super excited to have contributed with @evachrenkova.bsky.social to this amazing effort of @andre-rendeiro.com & @yimin-zheng.bsky.social for multimodal data integration: LazySlide!🧵👇

Andre Rendeiro @andre-rendeiro.com · Jun 1

🔬 Whole slide histopathology images are a goldmine for tissue biology and diagnostics - but too often locked away in inaccessible formats or tools. In our new preprint, we introduce LazySlide: an open-source, modular, and interoperable framework.
www.biorxiv.org/content/10.1...

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Reposted by Bernhard Zdársky

Nature @nature.com · May 19

Nature research paper: STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity

https://go.nature.com/4dhenKu

STAT5 and STAT3 balance shapes dendritic cell function and tumour immunity - Nature

Immune checkpoint blockade activates T cell immunity by reprogramming the STAT3 and STAT5 transcriptional pathways in dendritic cells, and STAT3 degradation is effective for treating tumours of multiple cancer types in mouse models.

go.nature.com

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