LightNews
amjeditor.bsky.social
Anaya Malik
@amjeditor.bsky.social
110 followers 360 following 240 posts
Editor & VP of Content of the American Medical Journal. Publisher of open access eJournals in Dermatology, Neurology, Respiratory, Oncology, Microbiology & ID, and Rheumatology content. Free subscription: https://www.emjreviews.com/en-us/amj/mailing-list/
www.emjreviews.com
Posts Media Videos Starter Packs
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 7h
🧪 Early data from a Phase II trial found that azelastine nasal spray reduced PCR-confirmed COVID-19 infections, signalling its potential role in respiratory virus prevention alongside vaccines.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #InfectiousDiseases @amjreviews.bsky.social
Azelastine Nasal Spray Shows Preventive Benefit
In a phase 2 randomized trial, azelastine nasal spray reduced PCR-confirmed SARS-CoV-2 infections versus placebo, with similar safety and fewer symptomatic infections observed during the 56-day preven...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 1d
⚠️ New evidence shows children with rheumatologic disease who are carefully weaned off long-term steroids face fewer adrenal crises, underscoring the importance of monitored tapering in clinical practice.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease
Children Weaned Off Steroids Avoid Crises
Retrospective study finds adrenal crisis is rare after weaning high dose glucocorticoids in children with nephrotic syndrome or juvenile idiopathic arthritis, supporting protocolized tapering under sp...
www.emjreviews.com
1 2
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 1d
🧬 New findings show animal exposure significantly increases treatment failure risk in brucellosis, stressing the importance of optimized drug regimens and targeted patient assessment to boost recovery rates.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #InfectiousDisease #Brucellosis
Animal Exposure to Treatment Failure: Optimized Regimens in Brucellosis
A network meta-analysis maps brucellosis treatment options and finds triple-drug regimens, especially with aminoglycosides, outperform common dual therapies for recovery. Results support updates to cl...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 2d
🚬 New insight: smoking may accelerate symptom progression in Huntington’s disease, with smokers experiencing a faster decline. Lifestyle counselling could be key to slowing neurological deterioration.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #HuntingtonsDisease #Neurodegeneration
Smoking Tied to Faster Huntington’s Decline
Analysis of Enroll-HD shows smoking is linked to earlier Huntington’s disease onset in women and faster motor and cognitive decline, supporting cessation advice for HD gene carriers.In Enroll-HD, smok...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 2d
🧪 Hidden culprit in younger CAP cases: Mycoplasma pneumoniae. Study finds it represents 33% of pneumonia in adults under 50 and is linked to delayed recognition and prior antibiotic use, highlighting diagnostic gaps.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #InfectiousDiseases #AMJ
Distinguishing Mycoplasma pneumoniae in Community-Acquired Pneumonia
Hospitalized adults with Mycoplasma pneumoniae CAP were younger with prolonged symptoms, highlighting the need for targeted testing and early empirical treatment strategies.
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 4d
📈 Quality of life is being overlooked in early-stage NSCLC research. Almost 50% of TKI and ICI trials don’t report QoL, missing a key measure of patient-centred care in curative treatment settings.

www.emjreviews.com/en-us/amj/on...

#AMJOncology #LungCancer #PatientOutcomes
Patient QoL Often Overlooked in Early-Stage NSCLC Research
A systematic review reveals poor assessment and reporting of health-related quality of life (HRQoL) in early-stage NSCLC trials testing tyrosine kinase and immune checkpoint inhibitors.
www.emjreviews.com
1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 4d
🧠🤖 ML predicts ICU readmission after stroke. Logistic reg leads (AUC 0.682); signals: steroid exposure, potassium, RBC count to guide follow-up.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #Stroke
Machine Learning Predicts ICU Readmission After Stroke
A retrospective study of 3,348 cerebral infarction patients shows machine learning can predict ICU readmission. Logistic regression performed best and highlighted modifiable clinical predictors for ri...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 8d
🍼 Could warming milk safeguard preterm infants? A new study will test if feeding milk at body temperature can reduce necrotizing enterocolitis (NEC), a severe gut disease that threatens very preterm babies.

www.emjreviews.com/en-us/amj/mi...

#AMJMicrobiology #Neonatology #InfectiousDiseases
Could Warm Milk Help Protect Preterm Infants from NEC?
A randomized trial will assess whether thermostatic milk feeding reduces necrotizing enterocolitis (NEC) and improves growth and feeding tolerance in very preterm infants.
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 8d
🧬 Updated lupus criteria improve diagnosis in autoimmune lung disease. Researchers found EULAR/ACR standards identified SLE more effectively than SLICC in patients with interstitial pneumonia with autoimmune features.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease #Lupus
New Criteria Improve Lupus Detection in Autoimmune Lung Disease
A new study finds that EULAR/ACR criteria identify more systemic lupus erythematosus cases among patients with interstitial pneumonia with autoimmune features than older methods.
www.emjreviews.com
1 1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 8d
🩸 Real-world findings show cutaneous venous malformations impact almost 200,000 Americans annually, far higher than expected. The study calls for better access to care and new treatment options.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #VascularAnomalies #RareDiseases
US Prevalence of Cutaneous Venous Malformations Higher Than Expected
A new nationally representative study estimates that cutaneous venous malformations affect nearly 200,000 Americans each year, underscoring unmet needs in care and treatment.
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 9d
🌍 Intelligent training could be key to ending cervical cancer. A global study found AI-powered learning tools boost colposcopy accuracy and clinician confidence, helping close training gaps worldwide.

www.emjreviews.com/en-us/amj/on...

#AMJOncology #CervicalCancer #AIinMedicine #WomensHealth
Intelligent Learning Tools Strengthen Global Cervical Cancer Training
A new intelligent digital training tool for colposcopy significantly improved diagnostic accuracy and confidence among clinicians worldwide, accelerating global cervical cancer elimination efforts.
www.emjreviews.com
1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 9d
🧠 New research shows cerebral venous sinus thrombosis (CVST) can lead to lasting neurological and psychiatric effects, including headaches, seizures, and depression, that may prevent many from resuming full-time employment.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #Stroke #MentalHealth
Post-Thrombosis Complications May Limit Return to Work
Survivors of cerebral venous sinus thrombosis frequently experience chronic headaches, seizures, depression, and cognitive impairment that hinder recovery and return to work.
www.emjreviews.com
1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 9d
🍭 Emerging research suggests that certain food additives could disrupt immune pathways and worsen inflammation in children with asthma, offering new clues into dietary impacts on respiratory health.

www.emjreviews.com/en-us/amj/re...

#AMJRespiratory #Asthma #Allergy #PediatricHealth
Food Additives May Disrupt Immune Balance in Asthmatic Children
New metabolomic research suggests certain food additives may disrupt immune metabolism, aggravating inflammation and asthma in children through altered T-cell and antigen-presenting cell function.
www.emjreviews.com
1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 10d
🧬 Gut microbes may hold the key to lung scarring in systemic sclerosis. An international study found distinct bacterial species linked to ILD severity, offering fresh insight into autoimmune mechanisms.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #AutoimmuneDisease
Study Connects Gut Microbes to Lung Scarring
International research reveals that specific gut bacteria are linked to the presence and severity of interstitial lung disease in systemic sclerosis, highlighting potential therapeutic targets within ...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 13d
💉✨ Helical tomotherapy plus paclitaxel delivers encouraging survival outcomes with reduced toxicity in cutaneous angiosarcoma, pointing to a safer treatment option than standard high-dose radiotherapy.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #Oncology
Combined Radiation and Chemotherapy Offer Safer Path in Angiosarcoma
Helical tomotherapy plus paclitaxel improved survival in cutaneous angiosarcoma with limited severe toxicity, offering a promising treatment approach compared to high-dose radiotherapy alone.
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 13d
👩‍🍼 Vaginal birth increases stress & mixed urinary incontinence risk, yet menopause alters the pattern. Before menopause, risk rises with each delivery; after, it remains significant only with 2+ births, showing hormonal influence on outcomes.

www.emjreviews.com/en-us/amj/ge...
Menopause Modifies Impact of Vaginal Birth on Urinary Incontinence
Study of U.S. women shows vaginal delivery increases stress and mixed urinary incontinence risk, with effects strongest before menopause and reduced but persistent after natural menopause.
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 14d
⚖️ Risk-reducing surgery prevents ovarian cancer in BRCA carriers, yet triggers early menopause and increases cardiovascular risk. Clinicians must balance cancer prevention with long-term heart health.

www.emjreviews.com/oncology/new...
Cancer Prevention Through Surgery Brings Menopause Forward
Risk-reducing surgery prevents ovarian cancer in BRCA and other hereditary cancer carriers but introduces premature menopause and increased cardiovascular risk, requiring integrated, long-term care st...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 14d
🧠💊 Omega-3 supplements reduced key markers of inflammation and oxidative stress in moderate-to-severe head injuries, but no improvement was seen in long-term recovery outcomes, researchers report.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #BrainInjury #Neuroinflammation
Omega-3s Reduce Inflammation but Not Outcomes in Head Injuries
Omega-3 supplementation lowered inflammatory and oxidative stress markers in moderate-to-severe head injury patients but did not improve long-term clinical outcomes, trial results show.
www.emjreviews.com
2
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 14d
🌫️ Indoor wood burning linked to lung risks. A major UK study finds affluent households using wood burners drive PM2.5 emissions, raising concerns over respiratory health and environmental justice.

Full story:
www.emjreviews.com/respiratory/...

#AMJRespiratory #LungHealth #AirPollution
Indoor Wood Burning in Affluent Areas Problematic for Lung Health
Indoor wood burning is linked to declining lung function, with UK data showing rising emissions, increased use among older adults, and concerning health risks for vulnerable populations.
www.emjreviews.com
1 1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 15d
⚠️ Sepsis remains a medical emergency, yet no screening tool works in isolation. NEWS/NEWS2 show strongest evidence, while qSOFA lags. Clinical judgment remains the cornerstone of diagnosis.

www.emjreviews.com/en-us/amj/mi...

#Sepsis
Why No Ideal Sepsis Tool Exists
Sepsis remains a medical emergency, but a new narrative review finds that no single screening tool reliably diagnoses it.
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 15d
🧠 Machine learning shows promise in tailoring knee osteoarthritis treatment. A new algorithm forecasts NSAID + paracetamol response with 85% accuracy, moving closer to personalized pain care.

www.emjreviews.com/en-us/amj/rh...

#AMJRheumatology #Osteoarthritis #PainManagement
New Algorithm Forecasts NSAID Efficacy for Knee Pain
Machine learning predicts pain relief in knee osteoarthritis with 85% accuracy by integrating pain sensitization, inflammation, microRNA, and psychological factors, advancing personalized management o...
www.emjreviews.com
1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 15d
🧬 Can biologic therapy be safely used in HS? A new analysis of adalimumab treatment found no hepatitis B or TB reactivation when patients received appropriate prophylaxis, supporting continued safe use.

www.emjreviews.com/en-us/amj/de...

#AMJDermatology #HidradenitisSuppurativa #Biologics
Can Biologic Therapy Be Safely Used in HS?
Adalimumab use in hidradenitis suppurativa patients showed no hepatitis B or tuberculosis reactivation when prophylaxis was provided, supporting its safe use with preventive screening and treatment.
www.emjreviews.com
1 2
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 16d
🧠 Weeks-long brainwave shift seen after Parkinson’s surgery. Beta power continued to rise for more than 3 weeks post-DBS, signaling a need to rethink early programming timelines.

www.emjreviews.com/en-us/amj/ne...

#AMJNeurology #ParkinsonsDisease
Weeks-Long Brainwave Shift Seen After Parkinson’s Surgery
Continuous recordings in Parkinson’s patients reveal that postoperative beta power rises for weeks after deep brain stimulation, offering new insight into the timing of the stun effect.
www.emjreviews.com
1
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 17d
🔎 Invasive gastric cancer may develop in unique ways after H. pylori eradication, appearing more often in the upper stomach and lacking map-like redness, which complicates early endoscopic surveillance and diagnosis.

www.emjreviews.com/microbiology...

#AMJMicrobiology #InfectiousDiseases
Invasive Gastric Cancer Patterns After H. pylori Eradication
Invasive gastric cancer after Helicobacter pylori eradication shows distinct traits including upper stomach location and absent map-like redness, underscoring the need for vigilant endoscopic surveill...
www.emjreviews.com
amjeditor.bsky.social
Anaya Malik @amjeditor.bsky.social · 21d
🫁 In lung critical care: severe necrotising infections may not need lung resection. A cohort recovered with optimal medical therapy, challenging surgical norms.

www.emjreviews.com/en-us/amj/re...
Hidden Threats: Donor-Derived Infections in Heart and Lung Transplants
Donor-derived infections remain a key challenge in heart and lung transplantation, with both established and emerging pathogens driving the need for vigilant screening and tailored management strategi...
www.emjreviews.com
2