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Ted Price @tedpricethepainguy.bsky.social · 1h

and here is some more evidence of mRNA transport in human DRG axons, just officially published today in @jci.org by @dianatavf.bsky.social www.jci.org/articles/vie...

JCI - Cell and molecular profiles in peripheral nerves shift toward inflammatory phenotypes in diabetic peripheral neuropathy

www.jci.org

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Ted Price @tedpricethepainguy.bsky.social · 1h

The whole idea for this came from a great discussion with Nathan Staff at a poster at the Peripheral Nerve Society meeting in Montreal two years ago.

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Ted Price @tedpricethepainguy.bsky.social · 1h

Sequencing these samples gives us important insight into changes in neuronal transcriptomes due to the axonally-transported mRNAs from these neurons that are abundant in these easy to obtain skin biopsies.

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Ted Price @tedpricethepainguy.bsky.social · 1h

Our study shows what I think can be possible if we use skin biopsies from neuropathic pain patients in a similar fashion to how tumor biopsies are analyzed in oncology.

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Ted Price @tedpricethepainguy.bsky.social · 1h

A great collaboration with Nathan Staff at Mayo Clinic and Sandra Rieger at The U (sorry, University of Miami will forever be The U to me). This project was led by Andy Wangzhou and @dianatavf.bsky.social at Center for Advanced Pain Studies.

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Ted Price @tedpricethepainguy.bsky.social · 1h

New preprint from us: Detection of probable neuronal gene expression changes in skin biopsies from patients with paclitaxel-induced peripheral neuropathy
www.biorxiv.org/content/10.1...

Detection of probable neuronal gene expression changes in skin biopsies from patients with paclitaxel-induced peripheral neuropathy

Our inability to obtain nerve samples from the vast majority of neuropathic pain patients impedes our ability to understand the disease, creates challenges in understanding mechanisms in specific pati...

www.biorxiv.org

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Ted Price @tedpricethepainguy.bsky.social · 2h

huge news for T-type Ca channels: ir.praxismedicines.com/news-release...

ir.praxismedicines.com

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Reposted by Ted Price

bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 17h

Detection of probable neuronal gene expression changes in skin biopsies from patients with paclitaxel-induced peripheral neuropathy https://www.biorxiv.org/content/10.1101/2025.10.15.682581v1

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Reposted by Ted Price

Derek Lowe @dereklowe.bsky.social · 21h

Never assume that you know all about what any drug molecule is doing in the body - where it's going, what it's binding to. A new example:

Rapamycin's Secrets

www.science.org

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Ted Price @tedpricethepainguy.bsky.social · 1d

Certain people just living in their home is now considered DEI in order to eliminate providing funds for basic safety of communities.

The New York Times @nytimes.com · 1d

Months before catastrophic floods swept through an Alaska Native village on Sunday, the Trump administration canceled a $20 million grant meant to protect the community from extreme flooding. At the time, the EPA administrator said he was eliminating "wasteful DEI and Environmental Justice grants."

E.P.A. Canceled $20 Million Flood Protection Grant to Alaska, Parts of Which Just Flooded

The remote village of Kipnuk planned to use the money to protect against flooding. On Sunday, it was inundated.

nyti.ms

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Reposted by Ted Price

Ewan St. John Smith @psalmotoxin.bsky.social · 2d

If evolution, comparative #neuroskyence & #PainResearch are your thing, here's a great review from Terry Walters: journals.biologists.com/jeb/article/...

From nociception in aneural animals to human suffering: toward a comparative biology of pain

Summary: The biology of widely shared and unusual features of human pain is informed by functional and mechanistic comparisons of nociception and pain-like aversive states across vertebrate and invert...

journals.biologists.com

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Ted Price @tedpricethepainguy.bsky.social · 4d

I never would have believed such a graph could be possible.

Prof Peter Hotez MD PhD DSc(hon) @peterhotezmdphd.bsky.social · May 30

No words

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Ted Price @tedpricethepainguy.bsky.social · 4d

Forrest Gump Point is for lovers

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Ted Price @tedpricethepainguy.bsky.social · 4d

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Ted Price @tedpricethepainguy.bsky.social · 4d

Kudos to the rangers keeping this place amazing despite the shutdown

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Ted Price @tedpricethepainguy.bsky.social · 4d

Greetings from Goosenecks State Park Utah

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Ted Price @tedpricethepainguy.bsky.social · 4d

Hello from Natural Bridges National Monument

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Ted Price @tedpricethepainguy.bsky.social · 5d

Good morning from a rainy monument valley

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Ted Price @tedpricethepainguy.bsky.social · 5d

The vicious disassembly of American health and science leadership continues with no real resistance from congress

Elizabeth Jacobs, PhD @elizabethjacobs.bsky.social · 5d

The editors of the CDC’s Morbidity and Mortality Weekly Report (MMWR) were apparently fired today.

The precursor to MMWR began in 1878 to address emerging public health threats rapidly.

We are not “great” without it. We are vulnerable to threats from sporadic foodborne illness to bioterrorism.

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Reposted by Ted Price

Jacob T. Levy @jacobtlevy.bsky.social · 6d

Four cheers for MIT.

orgchart.mit.edu/letters/rega...

Regarding the Compact | MIT Organization Chart

orgchart.mit.edu

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Reposted by Ted Price

SPARC @sparc.science · 6d

Check it out:
🔗 Paper: doi.org/10.1093/brai...
🔗 UTD Pain Center: paincenter.utdallas.edu
🔗 UTD Pain Center on SPARC: sparc.science/about/projec...

#Neuroscience #PainResearch #HEAL @tedpricethepainguy.bsky.social

Validate User

doi.org

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Ted Price @tedpricethepainguy.bsky.social · 6d

The graph and the short quote say it all!

Ardem Patapoutian @ardemp.bskyverified.social · 6d

"Immigrants, we get the job done"

www.economist.com/graphic-deta...

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Reposted by Ted Price

Tibor Rohacs @rohacstibor.bsky.social · 8d

The Rutgers Brain Health Institute @rutgersbhi.bsky.social is looking for an accomplished scientist to serve as the Director of the new Rutgers Center on Research in Pain and Pain Therapeutics. Feel free re-post and/or reach out to me if you have any questions
jobs.rutgers.edu/postings/225...

Director of Center on Research in Pain and Pain Therapeutics at Rutgers Brain Health Institute

We seek an accomplished scientist, at the Professor or Associate Professor level, to join the Rutgers Brain Health Institute (BHI) and The Rutgers School of Dental Medicine (RSDM) as Director of the n...

jobs.rutgers.edu

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Reposted by Ted Price

Dr. Sven-Eric Jordt #TobRegSky @sejordt.bsky.social · 7d

Omar Yaghi (Chemistry) is Palestinian, from a refugee family in Jordan

Michel Devoret (Physics) is French

John M. Martinis (Physics) is the son of Yugoslav immigrants

John Clarke (Physics) is British

@washingtonpost.com , this should be the message.

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Ted Price @tedpricethepainguy.bsky.social · 7d

Also this one is now officially available thanks to Asta Arendt-Tranholm and @ish1789.bsky.social sparc.science/datasets/475

SPARC Portal

The open community platform for bridging the body and the brain through neuroscience and systems physiology data, computational and spatial modeling, and device design.

sparc.science

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