Lightnews — Scholar-powered news

Paola A. Marignani

@pmarignani.bsky.social

910 followers 240 following 180 posts

Scientist & Professor. MarignaniLab.com Precision Oncology/Model Systems/Signal Transduction/Single Cell Transcriptomics/Informatics/sometimes athlete. Creative Destruction Lab (CDL) Scientist/Business Strategist ORCID: 0000-0001-8070-905X

Posts Media Videos Starter Packs

Paola A. Marignani @pmarignani.bsky.social · 1d

Post 🦃read.

www.nature.com/articles/s41...

Client Challenge

www.nature.com

Paola A. Marignani @pmarignani.bsky.social · 2d

Thanksgiving is always a time 4 me 2 reflect what it is 2 be Canadian, and 2 be grateful that my family chose 🇨🇦. The freedoms & liberties we share are part of the Canadian dream, a dream built on a foundation of multiculturalism, opportunity and mutual respect. 🍁🍂🇨🇦

Happy Thanksgiving. Be thankful

2 6

Paola A. Marignani @pmarignani.bsky.social · 3d

Stunning sunset #YQG Home for Thanksgiving.

Reposted by Paola A. Marignani

Canadian Women in STEM @cdnwomenstem.bsky.social · 4d

Looking for a job in STEM, our job board is up!
We update the site every 72 hours, so make sure you come back to it often.

Good luck with your job search.

canadianwomeninstem.org/job-board/

Canadian Women in STEM - Job Board

canadianwomeninstem.org

1 3 1

Paola A. Marignani @pmarignani.bsky.social · 4d

Impressive!

Albert Vilella, PhD. @albertvilella.bsky.social · 4d

I just posted this graph on bluesky this week: I think it was very illuminating of the bubbly state of AI recently.

Russ Wilcox @russwilcox.bsky.social · 4d

For example

Paola A. Marignani @pmarignani.bsky.social · 4d

@cdnwomenstem.bsky.social job board is up and running.

Check it out. #ScienceIsFun #ScienceSaves

Paola A. Marignani @pmarignani.bsky.social · 6d

Just another antipasto snack I made.

Paola A. Marignani @pmarignani.bsky.social · 7d

Metal-organic framework! Nobel for Chemistry. Fantastic news this morning.

Nature @nature.com · 7d

BREAKING: The Nobel Prize in Chemistry has been awarded to Susumu Kitagawa, Richard Robson and Omar M. Yaghi “for the development of metal-organic frameworks”

Stay tuned for more.
#NobelPrize

1 1

Reposted by Paola A. Marignani

Nature @nature.com · 9d

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"

Stay tuned for more.
#NobelPrize

1 98 230

Paola A. Marignani @pmarignani.bsky.social · 12d

FoM Town Hall-Strategic Focus

"What can we do to generate revenue" Dean Anderson Oct 2, 2025

@dalhousieu.bsky.social

Paola A. Marignani @pmarignani.bsky.social · 15d

Today I honour the Survivors of residential schools and remember the children who never came home. Reconciliation means listening, learning, and doing better. To Survivours: your stories matter, your resilience inspires. #Truth #Reconciliation #NDTR

2 5

Paola A. Marignani @pmarignani.bsky.social · 15d

Thank you Aya !
Your support has been impactful.
#ScienceIsFun

Aya @ayalan.bsky.social · 15d

Dr. Marignani's example has had a profound influence on me and countless others who have benefited from her generosity, mentorship, and passion for science. Congrats @pmarignani.bsky.social @dalhousie.bsky.social for being selected as a finalist for the Discovery Award Science Champion! 👩‍🔬

Reposted by Paola A. Marignani

McManusLab @kirkmcmanuslab.bsky.social · 18d

🚀 Exciting MSc opp @ UManitoba! Join 2 interdisciplinary labs (bioinformatics + cancer bio) on a CIHR-funded ovarian cancer project. Gain hands-on training in single-cell genomics & molecular biology. See advertisement to apply #GradResearch #Cancer

7 6

Paola A. Marignani @pmarignani.bsky.social · 20d

Public service announcement.

Paola A. Marignani @pmarignani.bsky.social · 22d

@dalhousieu.bsky.social Please consider welcoming Italians 🇮🇹 onto campus.

Benvenuti works well.

Paola A. Marignani @pmarignani.bsky.social · 22d

Dr. Chris McMaster shares his insight and experiences with biotech start-ups, innovation and commercialization. @dalinnovates.bsky.social

Paola A. Marignani @pmarignani.bsky.social · 22d

Gentle reminder for those of you searching for scholarships.

Remember to search your university website for scholarship opportunities, provincial and federal government websites.

Paola A. Marignani @pmarignani.bsky.social · Aug 29

Evening ocean kayaking. East coast calm.

Paola A. Marignani @pmarignani.bsky.social · Aug 27

Excited 2 invite those of you attending The International Association for the Study of Lung Cancer Conference to the workshop I organized. A wonderful opportunity 2 learn how cutting-edge innovations are translated 2 clinical practice
#WCLC2025 #IASLC

cattendee.abstractsonline.com/meeting/2115...

Paola A. Marignani @pmarignani.bsky.social · Aug 19

Webinar detailing new Tri-Council CV.

youtu.be/xeAk9Co8D2M?...

Tri-agency CV webinar

YouTube video by CIHR IRSC

youtu.be

Paola A. Marignani @pmarignani.bsky.social · Aug 19

☀️☕👩🏻‍💻 Shifting from Immunohistochemistry to Screen for ALK Rearrangements: Real-World Experience in a Large Single-Center Cohort of Patients with NSCLC
www.mdpi.com/2072-6694/16...

www.mdpi.com

Paola A. Marignani @pmarignani.bsky.social · Aug 17

Finally made it back to reformer Pilates at Iness new location at 2800 Argyle Street, Halifax.

My bones will thank me tomorrow.

Congrat Christy for your new location.

🧘🏻‍♀️🤸🏻‍♀️
www.iness.ca?gad_source=1...

Paola A. Marignani @pmarignani.bsky.social · Aug 15

Great opportunity for biotech wetlab biotech startup space. Check it out.

Athanor Scientific Inc. @athanorscientific.bsky.social · Aug 15

🍁👩‍🔬 Are you seeking wet lab space for your biotech startup or commercialized venture? We're exploring a pilot program to support 'biotech startups in residence,' offering reduced-cost resources and lab space to scientists and researchers.

Expression of interest form: forms.gle/ovjAEuXatigp...

Need wet lab space? Take this survey about our pilot Biotech Startup in Residence program.

Thank you for your interest in our biotech wet lab space survey. We are exploring the establishment of a shared wet lab facility on the campus of an independent grade-school in British Columbia, Canad...

forms.gle

Reposted by Paola A. Marignani

LKB1 (STK11) @stk11.bsky.social · Mar 12

Conclusions:
EDD E3 ubiquitin ligase levels increase progressively with BC progression.
EDD critical in regulating cell cycle progression & apoptosis; involved in promoting TORC1 signaling.
EDD knockdown in MCF-7 and T47D result in G2-phase arrest, decreased cell viability, and increased apoptosis.

1 1

Reposted by Paola A. Marignani

LKB1 (STK11) @stk11.bsky.social · Mar 12

EDD protein levels were assessed through immunostaining techniques in various breast tissue samples, including benign tissues and different grades of ductal carcinoma. This method helped establish the correlation between EDD expression and breast cancer progression. 📝

1 1 1