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Reposted by Alex Meraz

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 25d

And it’s live

Iptacopan in C3GN makes it to @thelancet.com

www.thelancet.com/journals/lan...

#NephSky

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Alex Meraz @nephroguy.bsky.social · Aug 5

Awesome congrats!!! Is this limited to losartan or it would be more a class effect of ARBs?

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Joel Topf @kidneyboy.bsky.social · Jul 14

Amazing to me that a seemingly acute event is either
A) has long-term sequellae despite being apparently resolving or
B) a dramatic and early presentation of profound endothelial disease

American Journal of Hypertension @amjhypertension.bsky.social · Jul 14

Effect of losartan on endothelial function in women with history of #preeclampsia

🔗 academic.oup.com/ajh/article/... 🔓

#OpenAccess #Free

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Alex Meraz @nephroguy.bsky.social · Jun 25

Amazing reference

Reposted by Alex Meraz

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · Jun 14

Way scarier story. Stories.

www.nytimes.com/2025/06/13/t...
(Gift link)

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · Jun 6

Sibeprenlimab in IgA Nephropathy #ERA25
* Data presented is the 9-month reduction in proteinuria

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Alex Meraz @nephroguy.bsky.social · Jun 5

Dr Meghan Sise presenting on serum cr/cystatin outcomes in patients treated with cisplatin or carboplatin

#Onconeph #ERA25

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Alex Meraz @nephroguy.bsky.social · Jun 5

Shite!

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · Jun 5

Hyperkalemia rates not lower with adding a flozin to the MRA 🤔

www.nejm.org/doi/full/10....

#ERA25

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · Jun 5

The first #ERA25 simultaneous pub

CONFIDENCE trial of empagliflozin + finerenone in N = 579

Greater reduction in ACR and BP
Note the impressive GFR dip

www.nejm.org/doi/full/10....

Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.

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NEJM.org @nejm.org · Jun 5

In the CONFIDENCE trial in persons with chronic kidney disease and type 2 diabetes, combination therapy with finerenone and empagliflozin led to a greater reduction in the urinary albumin-to-creatinine ratio than either drug alone. Full trial results: nej.md/4jEVbbk

#ERA25 #MedSky #Nephrology

A graph of the least-squares mean ratio of the change from baseline in the urinary albumin-to-creatinine ratio in the full analysis population.

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Alex Meraz @nephroguy.bsky.social · Jun 5

Missed it. Give us the highlights! #ERA25

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Alex Meraz @nephroguy.bsky.social · Jun 5

@kevinyau.bsky.social GLP1 agonist master Jedi presenting at #ERA25.

💉GLP1 agonist reduce ED visits and hospitalizations!!!

📉Awesome methods. Best of the session:

💊DDP4 for comparison, IPTW, ICES data. Ticking all the right boxes (EPI nerd).

💊Only 40% on SGLT2i!!! We should flozinate more!!!

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Alex Meraz @nephroguy.bsky.social · Jun 5

@kevinyau.bsky.social @armelleid.bsky.social

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Alex Meraz @nephroguy.bsky.social · Jun 5

I wish we had any of the new treatments in Canada. Any.

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Alex Meraz @nephroguy.bsky.social · Jun 5

#ERA25 baby!!!

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · Jun 3

Experiential Evidence of Systemic Racism for Indigenous Peoples Navigating Transplantation in Canada - in @kireports.bsky.social

www.kireports.org/article/S246...

#NephSky

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Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · Jun 3

The US spends billions of dollars on binders every year

We are doing the RCT to get you the answer - more than 3000 enrolled

ajkdblog.org/2021/06/16/c... and www.nephjc.com/news/2021/2/...

Could High Be Better Than Low? Targeting Phosphate in Trials

Phosphate is bad, right? As kidney function declines, phosphate excretion goes down. Serum phosphate levels rise, causing parathyroid hormone (PTH) to increase and bring phosphate down. Phosphate h…

ajkdblog.org

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Alex Meraz @nephroguy.bsky.social · May 12

I am not going. But see you in Vienna!!!!

Alex Meraz @nephroguy.bsky.social · Apr 4

I feel you pain bro.

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Alex Meraz @nephroguy.bsky.social · Apr 2

Read the same in Brener’s book long time ago

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ASN Publications @asnpublications.bsky.social · Jan 15

Torsemide is proposed to have clinically important pharmacokinetic and pharmacodynamic advantages over furosemide. This study found no meaningful pharmacokinetic/pharmacodynamic advantages for torsemide versus furosemide. bit.ly/JASN0481

Visual abstract for "Mechanistic Differences between Torsemide and Furosemide."

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Renal Failure @renalfailuretf.bsky.social · Jan 5

Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production

#Nephrology #endocrinology #Diabetes #SGLT2i #NephSky

www.tandfonline.com/doi/full/10....

Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production

Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease. Sodium-glucose cotransporter protein 2 inhibitors (SGLT2i) are antihyperglycemic agents that provide additional renal-...

www.tandfonline.com

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Alex Meraz @nephroguy.bsky.social · Dec 26

D obviously

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Kidney Medicine Journal @kidneymed.bsky.social · Dec 22

Case report:
Daratumumab for Bortezomib-Refractory Proliferative Glomerulonephritis With Monoclonal Immunoglobulin Deposits in Kidney Allograft: A Case Report

https://buff.ly/3P5dsSc

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