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Nature Biotechnology @natbiotech.nature.com · 30m

Stem cell technique could preserve endangered bird species #NBTintheNews via @caltech.edu www.caltech.edu/about/news/s...

Stem Cell Technique Could Preserve Endangered Bird Species

A new technique enables stem cells from bird species to be frozen and revived

www.caltech.edu

Nature Biotechnology @natbiotech.nature.com · 13h

Spermatid-like haploid stem cells produce genome-edited farm animals in one generation #NBTNV go.nature.com/4mR49nv
rdcu.be/eJ3JN

Client Challenge

go.nature.com

Nature Biotechnology @natbiotech.nature.com · 17h

AI-designed proteins surpass nature in genome editing #NBTintheNews dig.watch/updates/ai-d...

AI-designed proteins surpass nature in genome editing | Digital Watch Observatory

The discovery could accelerate gene and cell therapies for cancer and rare diseases.

dig.watch

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Nature Biotechnology @natbiotech.nature.com · 18h

Programmable promoter editing for precise control of transgene expression - @mitcheme.bsky.social @mitdeptofbe.bsky.social go.nature.com/4h9wlR1

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Nature Biotechnology @natbiotech.nature.com · 18h

Engineered pattern recognition receptors enhance broad-spectrum plant resistance - @zmbp-tuebingen.bsky.social go.nature.com/474nnA9

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Nature Biotechnology @natbiotech.nature.com · 3d

Generative AI designs synthetic gene editing proteins better than nature #NBTintheNews www.insideprecisionmedicine.com/topics/trans...

Generative AI Designs Synthetic Gene Editing Proteins Better than Nature

Their use of generative AI focused on PiggyBac transposases and uncovered more than 13,000 previously unidentified PiggyBac sequences.

www.insideprecisionmedicine.com

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Nature Biotechnology @natbiotech.nature.com · 4d

Durable epigenetic silencing with a TALE-based editor #NBTNV - @stanleyqilab.bsky.social go.nature.com/4q3YvRE

Durable epigenetic silencing with a TALE-based editor - Nature Biotechnology

Transient expression of a transcription activator-like effector (TALE)-based epigenetic editor demonstrates durable therapeutic silencing in non-human primates.

go.nature.com

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Nature Biotechnology @natbiotech.nature.com · 4d

A method to produce embryonic stem cells for a range of bird species opens up opportunities in agriculture, developmental biology and species conservation #NBTNV go.nature.com/4ntGnih
rdcu.be/eJagy

Embryonic stem cells across bird species - Nature Biotechnology

A method to produce embryonic stem cells for a range of bird species opens up opportunities in agriculture, developmental biology and species conservation.

go.nature.com

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Nature Biotechnology @natbiotech.nature.com · 4d

Study finds generative AI outperforms nature in protein design #NBTintheNews www.biopharminternational.com/view/study-f...

Study Finds Generative AI Outperforms Nature in Protein Design | BioPharm International

The study by Integra Therapeutics and partners reveals how AI-engineered proteins could expand gene-editing tools and streamline development of advanced therapies.

www.biopharminternational.com

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Nature Biotechnology @natbiotech.nature.com · 5d

FLiP–MS uses a library of protein–protein interaction markers to understand protein complex dynamics go.nature.com/4dQabQw
rdcu.be/eJI3A

Global profiling of protein complex dynamics with an experimental library of protein interaction markers - Nature Biotechnology

FLiP–MS uses a library of protein–protein interaction markers to understand protein complex dynamics.

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Nature Biotechnology @natbiotech.nature.com · 5d

Generative AI surpasses nature in designing proteins for genome editing #NBTintheNews bioengineer.org/generative-a...

Generative AI Surpasses Nature in Designing Proteins for Genome Editing

In an extraordinary leap forward for the field of genetic engineering, researchers at Integra Therapeutics, in collaboration with the Pompeu Fabra University (UPF) Department of Medicine and Life

bioengineer.org

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Nature Biotechnology @natbiotech.nature.com · 5d

Genome-edited farm animals from haploid stem cells #NBTNV go.nature.com/4mR49nv

Genome-edited farm animals from haploid stem cells - Nature Biotechnology

Spermatid-like haploid stem cells produce genome-edited farm animals in one generation.

go.nature.com

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Nature Biotechnology @natbiotech.nature.com · 5d

Site-specific and efficient RNA editing is achieved with a CasRx editor go.nature.com/4dFun7P
rdcu.be/eJI3u

A circularly permuted CasRx platform for efficient, site-specific RNA editing - Nature Biotechnology

Site-specific and efficient RNA editing is achieved with a CasRx editor.

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Nature Biotechnology @natbiotech.nature.com · 6d

From cancer to Alzheimer’s: decoding RNA-protein signals #NBTintheNews neurosciencenews.com/rna-mapping-...

From Cancer to Alzheimer’s: Decoding RNA-Protein Signals - Neuroscience News

Scientists have created a breakthrough technology that reveals the entire network of RNA-protein interactions in human cells, offering new insights into how diseases develop.

neurosciencenews.com

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Nature Biotechnology @natbiotech.nature.com · 6d

USC Stem Cell-led study generates authentic embryonic stem cell from birds #NBTintheNews stemcell.keck.usc.edu/study-genera...

USC Stem Cell-led study generates authentic embryonic stem cell from birds

Egg whites may be perfect for a health-conscious breakfast, but egg yolks turned out to be the key ingredient for cultivating bird embryonic stem cells (ESCs) in the lab. Using a growing medium of egg...

stemcell.keck.usc.edu

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Nature Biotechnology @natbiotech.nature.com · 6d

Folding-mediated secretion of pure bispecific antibodies go.nature.com/48NEM2o

Folding-mediated secretion of pure bispecific antibodies - Nature Biotechnology

Mutation of conserved prolines enhances correct pairing of light and heavy chains for bispecific IgG-like antibody production.

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Nature Biotechnology @natbiotech.nature.com · 6d

Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells go.nature.com/42wdD05

Generation of modified cows and sheep from spermatid-like haploid embryonic stem cells - Nature Biotechnology

Haploid embryonic stem cells for cattle and sheep are produced, opening new reproductive possibilities.

go.nature.com

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Nature Biotechnology @natbiotech.nature.com · 7d

Generative AI pushes gene editing beyond nature’s limits #NBTintheNews firstwordpharma.com/story/6241404

firstwordpharma.com

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Nature Biotechnology @natbiotech.nature.com · 7d

Mapping RNA-protein ‘chats’ could uncover new treatments for cancer and brain disease #NBTintheNews today.ucsd.edu/story/mappin...

Mapping RNA-Protein ‘Chats’ Could Uncover New Treatments for Cancer and Brain Disease

A technology that maps entire networks of RNA-protein interactions inside human cells could offer new strategies for treating diseases ranging from cancer to Alzheimer's.

today.ucsd.edu

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Nature Biotechnology @natbiotech.nature.com · 7d

Avian embryonic stem cells derived using egg yolk-based culture #NBTintheNews www.genengnews.com/topics/trans...

Avian Embryonic Stem Cells Derived Using Egg Yolk-Based Culture

Researchers generate authentic embryonic stem cells from birds using an egg yolk-based culture along with a few other key factors.

www.genengnews.com

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Nature Biotechnology @natbiotech.nature.com · 7d

Generative AI is more efficient than nature at designing proteins to edit the genome #NBTintheNews integra-tx.com/generative-a...

AI is more efficient than nature at designing proteins to edit genome

This work led by Integra Therapeutics, a global pioneer published today in the journal "Nature Biotechnology".

integra-tx.com

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Reposted by Nature Biotechnology

César de la Fuente @delafuentelab.bsky.social · 11d

Thank you so much for highlighting our latest work!

Nature Biotechnology @natbiotech.nature.com · 13d

Research Highlight: Mining archaea for antibiotics www.nature.com/articles/s41...

Mining archaea for antibiotics - Nature Biotechnology

Nature Biotechnology - Mining archaea for antibiotics

www.nature.com

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Reposted by Nature Biotechnology

Dimitrije @biodimi.bsky.social · 11d

Check out our latest work on the discovery and engineering of PiggyBac transposases! 🧵

Nature Biotechnology @natbiotech.nature.com · 11d

Discovery and protein language model-guided design of hyperactive transposases - @marcguellc.bsky.social @upf.edu @icreacommunity.bsky.social @crg.eu go.nature.com/4gXLGEw

Discovery and protein language model-guided design of hyperactive transposases - Nature Biotechnology

Phylogenetic mining and protein language models uncover improved PiggyBac transposase sequences.

go.nature.com

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Reposted by Nature Biotechnology

Universitat Pompeu Fabra @upf.edu · 12d

#Recerca

Ja és possible dissenyar proteïnes completament sintètiques amb #IA per editar el genoma

Nou estudi d’Integra Therapeutics, el Laboratori de Biologia Sintètica @marcguellc.bsky.social, i el Grup de Disseny de Proteïnes amb IA del @crg.eu, publicat a @natbiotech.nature.com

tuit.cat/d0olZ

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Nature Biotechnology @natbiotech.nature.com · 10d

The COP16 decision established a multilateral mechanism for digital sequence information benefit-sharing. DSI researchers assess what has been accomplished so far and identify remaining challenges go.nature.com/4nBE4t8
rdcu.be/eJnid

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