Chris Marine Lab
@marinelab.bsky.social
1.5K followers 310 following 20 posts
Cancer research
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Just like there are good and bad macrophages..., there are good and bad NK cells!! This has profound therapeutic implications, far beyond oncology! Thanks to CD for highlighting both papers and the superb and efficient editorial work! Thanks to our collaborators (especially Zihai Li) and funders!
Now online in Cancer Discovery for the #EACR2025 presentation by @marinelab.bsky.social: Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype doi.org/10.1158/2159... @vib-ccb.bsky.social @pozniakjoanna.bsky.social
Unmissable for those working on melanoma and beyond.
The SMR 2025 Annual Congress (Amsterdam Oct 25-28) covers basic, preclinical & translational melanoma research of international top investigators. It is a very enjoyable conference with top faculty and now improved with ample opportunity for young investigators to network. Join us! smrcongress.org
Society Melanoma Research Congress
smrcongress.org
Reposted by Chris Marine Lab
Now online in Cancer Discovery for the #EACR2025 presentation by @marinelab.bsky.social: Cytotoxic NK Cells Impede Response to Checkpoint Immunotherapy in Melanoma with an Immune-Excluded Phenotype doi.org/10.1158/2159... @vib-ccb.bsky.social @pozniakjoanna.bsky.social
Very excited to see our new study out today - just in time for my talk annual EACR conference @helloeacr.bsky.social
Christophe Marine @marinelab.bsky.social @vib-ccb.bsky.social presenting his hot-off-the-presses Cancer Discovery paper today at #EACR2025!
rdcu.be/emi9N
Fishing for Metastasis Initiating Cells (MICs): we summarize here a heroic effort from Christoph Klein and Melanie Werner-Klein labs, which describes a MIC population in lymph nodes and how these cells evade immune attack. #metastasis #melanoma #extracellularvesicles #cancerprevention
Fishing for melanoma metastasis-initiating cells in lymph nodes
Nature Cancer - The complex nature of metastasis-initiating cells (MICs) has long hindered our understanding of how cancer spreads and how to prevent it. A study now identifies a potential MIC...
rdcu.be
Reposted by Chris Marine Lab
“Science has no passport, no gender, no ethnicity, no political party.”

EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent.

In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.
We are really looking forward to hosting YOU and these amazing speakers in Leuven. Whether you are a young trainee, an experienced postdoc or a leader in the field, please join us (you will not regret this!).
The VIB Conference on Tumor Heterogeneity, Plasticity, & Therapy is back (3rd edition) on Dec 10-12 in Leuven! Join us at #THPT25 for 2 days of pioneering research & discussions on #tumorbiology and #cancertherapy resistance. Be part of the conversation: vibbio.tech/3DLsomq.
@vib-ccb.bsky.social
An important step towards personalised (combination) cancer treatments. vib.be/en#/ We are very excited about this project! Thanks to Oliver Bechter and his team and Presage for their trust and vision.
Great talk from my friend and colleague @cedric-blanpain.bsky.social (Chemoresistance) at the @helloeacr.bsky.social conference on Drug Tolerant Persister Cells (Lyon, France). Thanks to the organizers for this exciting event.
Please join us for this exciting event!!! Very much looking forward to the great talks and discussions on this 🔥 topic
Registration and abstract submission is now open for Cancer Cell Plasticity: Cracking the Code of Adaptation and Survival!

Join us online on 02-03 December for a jam-packed programme discussing the latest discoveries in this field.

eacr.org/conference/c...
Our latest piece "Decoding Melanoma’s Cellular Mosaic to Unlock Immunotherapy Potential" is available online: authors.elsevier.com/a/1khFK3QxxS... and will soon be published in @cp-trendscellbio.bsky.social. Thanks to @pozniakjoanna.bsky.social for taking the lead! Our Cover design proposal is below
Reposted by Chris Marine Lab
Breaks are key to relaxed & unwind between sessions! This afternoon, @juliensage.bsky.social hit the courts with @marinelab.bsky.social & Lukas Dow - what better way to reset than a (maybe not so) friendly game of tennis🎾 #AMC25
Our excellent host, Julien Sage, sharing a surprising/unexpected role for T cells in the biology of small cell lung cancer …thanks Julien and Kevin for organising such a great @fusionconf.bsky.social (mouse models of cancer) conference!!
Reposted by Chris Marine Lab
We took a deep dive into cancer progressions & metastasis this morning at #AMC25:
🧬Chris Marine on melanoma progression & therapy resistance
🐭 Eran Andrechek & Peter Westcott with cutting edge mouse models
🫁Katie Politi on progression & resistance in lung cancer
🌊Plus an exciting Catamaran tour⛵️
So cool!!
🔈We've got the cover of the 2nd NG issue for 2025🙌
Read about the cover: In the comment👇
Also check out our research briefing🚨 (link below):
nature.com/articles/s41...
nature.com/articles/s41...
So happy to see this live, Slim! Congratulations to you, Ernesto and the whole team for your resilience, vision and creativity!
Thrilled to share my 1st brainchild, out today @naturegenet.bsky.social 🚀 Been hearing a lot about fetal-like states lately? We uncover the molecular mechanisms, functional significance and clinical relevance of #oncofetal reprogramming in CRC. www.nature.com/articles/s41... (rdcu.be/d9iSN) a 🧵
Reposted by Chris Marine Lab
1) Huge thanks to @guccionelab.bsky.social @nickbarker @marinelab.bsky.social @ggargiul.bsky.social
@owensansom 4 the fantastic collaboration. NIH funding #EarlyStageInvestigator. Towards #BetterTherapeuticStrategies 4 #CRC patients #Oncofetal #CRC #IntratumoralHeterogeneity #PhenotypicPlasticity
Congratulations, Mark & co, on this beautiful and very important piece!
Congratulations Ginevra and the whole Fendt team! This is very exciting work!
Reposted by Chris Marine Lab
End-of-the-year preprint & first 🧵 where the sky is blue! Ever wondered how a cancer driven by a single mutant oncogene becomes molecularly & cellularly heterogeneous? Why metastases share drivers w/primary tumors but are more aggressive?
Auguri, Andrea! Congrats to the whole lab!!
Looking for an enthusiastic bioinformatician (long-term postdoctoral follow or staff scientist) interested in cancer/melanoma biology and therapy resistance. Data Science (single-cell, spatial multiomics integration), Machine learning, R, Pyhthon... jobso.id/ik9e
Bioinformatician Postdoctoral Level - VIB
Position summary The Chris Marine lab at the VIB Center for Cancer Biology (https://ccb.sites.vib.be/en) is actively seeking a skilled bioinformatician proficient in analyzing and integrating single-...
jobso.id
Congratulations, Yael and team!
Congratulations, Anna and team!